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List of works by James G Jackson

A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development ⬇️

scientific article published on September 14, 2010

Analysis across multiple tumor types provides no evidence that mutant p53 exerts dominant negative activity

article

BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer

scientific article published on 26 May 2020

Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

scientific journal article

Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment

scientific article published on 01 October 2018

Che-ating death: CHE1/AATF protects from p53-mediated apoptosis ⬇️

scientific article published on September 7, 2012

Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

scientific article published on 17 September 2019

Correlation of Insulin-Like Growth Factor-Binding Protein-3 Messenger RNA With Protein Expression in Primary Breast Cancer Tissues: Detection of Higher Levels in Tumors With Poor Prognostic Features

scientific article published in May 1996

Detection of insulin-like growth factor binding proteins (IGFBPs) by ligand blotting in breast cancer tissues

scientific article published in February 1994

Engulfment and cannibalism drive persistence of chemotherapy-treated tumor cells: can they be targeted?

scientific article published on 10 December 2019

Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expressionin Vitroandin Vivo

scientific article published in May 1999

Expression of insulin-like growth factor binding proteins in human breast cancer correlates with estrogen receptor status

scientific article published in June 1993

FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter1

scientific article published in July 1999

IRS-1 expression and activation are not sufficient to activate downstream pathways and enable IGF-I growth response in estrogen receptor negative breast cancer cells

scientific article published in October 1999

Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

scientific article published on 17 April 1998

Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells

scientific article published on 01 January 1994

Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival

scientific article published on 01 January 1997

MRG15 regulates embryonic development and cell proliferation

scientific article

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity

scientific article published on November 2010

Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.

scientific article

Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells

scientific article published on April 2006

Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

scientific article published on November 1993

Regulation of Insulin-Like Growth Factor-Binding Protein (IGFBP) Expression by Breast Cancer Cells: Use of IGFBP-1 as as Inhibitor of Insulin-like Growth Factor Action

scientific article published on 2 September 1992

Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines ⬇️

scientific article published on November 1, 2001

Regulation of insulin-like growth factor binding proteins in ovarian cancer cells by oestrogen.

scientific article published on January 1993

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo.

scientific article published on 18 October 2010

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation

scientific article

SASP: Tumor Suppressor or Promoter? Yes!

scientific article published on 24 October 2016

TNBC invasion: downstream of STAT3.

scientific article published on 10 February 2017

TP53 Mutations and Outcomes in Breast Cancer: Reading beyond the Headlines

scientific article published on 05 February 2020

The Regulation of Cellular Functions by the p53 Protein: Cellular Senescence

scientific article published on 23 November 2016

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

scientific article

Use of Insulin-like Growth Factor-I Gene Expression to Distinguish Between Breast and Ovarian Cancer

scientific article published in February 1994

p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer

scientific article published on 31 May 2018

p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts

scientific article published on 01 September 2006

p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

scientific article

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