List of works - David Levens

An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis

scientific article published on February 2006

CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome

scientific article published on 07 January 2014

ChIP bias as a function of cross-linking time

scientific article published on 21 December 2015

Controlling gene expression by DNA mechanics: emerging insights and challenges

scientific article

Controlling gene expression by DNA mechanics: emerging insights and challenges

article

Cooperative epigenetic modulation by cancer amplicon genes

scientific article

Correction: Teasing Apart Translational and Transcriptional Components of Stochastic Variations in Eukaryotic Gene Expression.

scientific article published on 8 October 2012

DNA break mapping reveals topoisomerase II activity genome-wide

scientific article

DNA topoisomerases beyond the standard role.

scientific article published on September 2013

DNA topology and transcription

scientific article

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition

scientific article

Dissecting transcriptional amplification by MYC

scientific article published on 27 July 2020

Enhancers not required

scientific article

FBPs are calibrated molecular tools to adjust gene expression

scientific article

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells

scientific article published on 01 October 2020

Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels.

scientific article published on 13 January 2016

GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy

scientific article published on 16 March 2016

Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples.

scientific article published on 25 November 2015

Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response

scientific article published on 30 August 2017

Global regulation of promoter melting in naive lymphocytes

scientific article published on May 2013

H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation.

scientific article published on 20 December 2012

Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein

scholarly article

Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression

scientific article published on 17 April 2013

JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress

scientific article

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome"

scientific article published on 09 December 2021

MYC protein stability is negatively regulated by BRD4

scientific article published on 01 June 2020

Mapping DNA Breaks by Next-Generation Sequencing

scientific article published in January 2018

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

scientific article published on 28 July 2017

Notching up MYC gives a LIC.

scientific article published on July 2013

Partition of Myc into immobile vs. mobile complexes within nuclei

scientific article published on January 2013

Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome

scientific article

Potential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation

scientific article

RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription

scientific article

Rapid genome-scale mapping of chromatin accessibility in tissue

scientific article

Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation

scientific article

SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.

scientific article published on 11 April 2012

Shapely DNA attracts the right partner

scientific article

Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules

scientific article published on 01 July 2019

Synergistic effect of non-transmissible Sendai virus vector encoding the c-myc suppressor FUSE-binding protein-interacting repressor plus cisplatin in the treatment of malignant pleural mesothelioma.

scientific article published on 9 May 2011

TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression

scientific article

Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression

scientific article

The Energetics and Physiological Impact of Cohesin Extrusion

scientific article published on 26 April 2018

The Energetics and Physiological Impact of Cohesin Extrusion

scientific article published on 01 September 2018

The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression

scientific article

The Texture of Chromatin

scientific article published on 01 October 2019

The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling

scientific article published in January 2018

The dynamic response of upstream DNA to transcription-generated torsional stress

scientific article

The functional response of upstream DNA to dynamic supercoiling in vivo

scientific article

The genome-wide distribution of non-B DNA motifs is shaped by operon structure and suggests the transcriptional importance of non-B DNA structures in Escherichia coli

scientific article

The importance of being supercoiled: how DNA mechanics regulate dynamic processes

scientific article

Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

scientific article

Transcription-dependent dynamic supercoiling is a short-range genomic force

scientific article published on 17 February 2013

Tuning the MYC response.

scientific article published on 27 July 2016

Ups and Downs of Poised RNA Polymerase II in B-Cells

scientific article

Visualizing structure-mediated interactions in supercoiled DNA molecules.

scientific article

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

scientific article

List of works by David Levens

An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis

CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome

ChIP bias as a function of cross-linking time

Controlling gene expression by DNA mechanics: emerging insights and challenges

Controlling gene expression by DNA mechanics: emerging insights and challenges

Cooperative epigenetic modulation by cancer amplicon genes

Correction: Teasing Apart Translational and Transcriptional Components of Stochastic Variations in Eukaryotic Gene Expression.

DNA break mapping reveals topoisomerase II activity genome-wide

DNA topoisomerases beyond the standard role.

DNA topology and transcription

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition

Dissecting transcriptional amplification by MYC

Enhancers not required

FBPs are calibrated molecular tools to adjust gene expression

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells

Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels.

GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy

Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples.

Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response

Global regulation of promoter melting in naive lymphocytes

H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation.

Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein

Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression

JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome"

MYC protein stability is negatively regulated by BRD4

Mapping DNA Breaks by Next-Generation Sequencing

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

Notching up MYC gives a LIC.

Partition of Myc into immobile vs. mobile complexes within nuclei

Permanganate/S1 Nuclease Footprinting Reveals Non-B DNA Structures with Regulatory Potential across a Mammalian Genome

Potential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation

RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription

Rapid genome-scale mapping of chromatin accessibility in tissue

Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation

SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.

Shapely DNA attracts the right partner

Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules

Synergistic effect of non-transmissible Sendai virus vector encoding the c-myc suppressor FUSE-binding protein-interacting repressor plus cisplatin in the treatment of malignant pleural mesothelioma.

TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression

Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression

The Energetics and Physiological Impact of Cohesin Extrusion

The Energetics and Physiological Impact of Cohesin Extrusion

The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression

The Texture of Chromatin

The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling

The dynamic response of upstream DNA to transcription-generated torsional stress

The functional response of upstream DNA to dynamic supercoiling in vivo

The genome-wide distribution of non-B DNA motifs is shaped by operon structure and suggests the transcriptional importance of non-B DNA structures in Escherichia coli

The importance of being supercoiled: how DNA mechanics regulate dynamic processes

Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

Transcription-dependent dynamic supercoiling is a short-range genomic force

Tuning the MYC response.

Ups and Downs of Poised RNA Polymerase II in B-Cells

Visualizing structure-mediated interactions in supercoiled DNA molecules.

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells