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2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis
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2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
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A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds
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Are active and passive smoking harmful? Determining causation
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Arthroscopic surgery for knee pain
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Arthroscopic surgery for knee pain
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Bleeding Risk in Atrial Fibrillation Patients Taking Vitamin K Antagonists: Systematic Review and Meta-Analysis
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Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors
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Certainty ranges facilitated explicit and transparent judgments regarding evidence credibility
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Change in albuminuria as a surrogate endpoint in chronic kidney disease
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Evidence vs Consensus in Clinical Practice Guidelines
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Evidence, values & masks for control of COVID-19
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Evidence-Based Clinical Practice
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Evidence-Based Emergency Medicine
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Evidence-Based Health Care as a Model for Decision Making
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Evidence-based Health Care
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Evidence-based diagnosis in endocrinology
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Evidence-based emergency medicine. The clinician and the medical literature: when can we take a shortcut?
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Evidence-based endocrinology
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Evidence-based guidelines for supportive care of patients with Ebola virus disease
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Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
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Evidence-based management of patients with osteoporosis
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Evidence-based medicine 20 years on: a view from the inside
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Evidence-based medicine in anesthesiology
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Evidence-based medicine in times of crisis
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Evidence-based medicine targets the individual patient, part 1: how clinicians can use study results to determine optimal individual care
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Evidence-based medicine targets the individual patient, part 2: guides and tools for individual decision-making
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Evidence-based medicine targets the individual patient. Part 1: how clinicians can use study results to determine optimal individual care
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Evidence-based medicine targets the individual patient. Part 2: Guides and tools for individual decision-making
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Evidence-based practice is not synonymous with delivery of uniform health care
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Evidence-based practice targets the individual patient. Part 1: how clinicians can use study results to determine optimal individual care
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Evidence-based practice: what it is, why we need it.
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Executive summary: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
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Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
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Experience with GRADE
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Experiences with a novel policy for managing conflicts of interest of guideline developers: a descriptive qualitative study
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Expertise in recall of clinical protocols in two specialty areas.
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Exploration of the value of health-related quality-of-life information from clinical research and into clinical practice
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Exploratory factor analysis of the Brazilian OHIP for edentulous subjects
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FIT for FUNCTION: study protocol for a randomized controlled trial
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Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies.
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Factors Associated with Health-Related Quality of Life in Patients with Open Fractures
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Factors affecting physicians' decisions on caring for an incompetent elderly patient: an international study
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Factors associated with the duration of disability benefits claims among Canadian workers: a retrospective cohort study
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Factors influencing decision making in neonatology: inhaled nitric oxide in preterm infants
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Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*.
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Failure to place evidence at the centre of quality improvement remains a major barrier for advances in quality improvement
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Family impact of child oral and oro-facial conditions
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Feasibility of behavioral activation group therapy in reducing depressive symptoms and improving quality of life in patients with depression: the BRAVE pilot trial
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Fiber for the treatment of hemorrhoids complications: a systematic review and meta-analysis
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First-line treatment of seasonal (ragweed) rhinoconjunctivitis. A randomized management trial comparing a nasal steroid spray and a nonsedating antihistamine.
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Fluid Resuscitation in Sepsis
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Fluid lavage of open wounds (FLOW): a multicenter, blinded, factorial pilot trial comparing alternative irrigating solutions and pressures in patients with open fractures
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Fluid resuscitation in severe sepsis and septic shock: systematic description of fluids used in randomized trials
Fluid type and the use of renal replacement therapy in sepsis: a systematic review and network meta-analysis.
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Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial
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Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial
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Four of the authors respond
Framework of policy recommendations for implementation of evidence-based practice: a systematic scoping review
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Frequency and methodologic rigor of quality-of-life assessments in the critical care literature
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GRADE Equity Guidelines 2: Considering health equity in GRADE guideline development: Equity extension of the Guideline Development Checklist
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GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction
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GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction
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GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines
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GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines
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GRADE Guidelines 28: Use of GRADE for the assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks
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GRADE Guidelines 30: The GRADE Approach to Assessing the Certainty of Modelled Evidence - an Overview in the Context of Health Decision-making
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GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health
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GRADE Guidelines: 18. How ROBINS-I and other tools to assess risk of bias in non-randomized studies should be used to rate the certainty of a body of evidence.
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GRADE Guidelines: 19. Assessing the certainty of evidence describing the relative importance of outcomes or values and preferences -- Risk of bias and indirectness
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GRADE approach to drawing conclusions from a network meta-analysis using a minimally contextualised framework
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GRADE approach to drawing conclusions from a network meta-analysis using a partially contextualised framework
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GRADE approach to rate the certainty from a network meta-analysis: addressing incoherence
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GRADE approach to rate the certainty from a network meta-analysis: avoiding spurious judgments of imprecision in sparse networks
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GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale
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GRADE equity guidelines 3: considering health equity in GRADE guideline development: rating the certainty of synthesized evidence
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GRADE equity guidelines 4: guidance on how to assess and address health equity within the evidence to decision process.
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GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence
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GRADE guidelines 26: informative statements to communicate the findings of systematic reviews of interventions
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GRADE guidelines 6. Rating the quality of evidence—imprecision
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GRADE guidelines system is reproducible when instructions are clearly operationalized even among the guidelines panel members with limited experience with GRADE.
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GRADE guidelines-an introduction to the 10th-13th articles in the series
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GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
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GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence
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GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes
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GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes
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GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes
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GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations
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GRADE guidelines: 15. Going from evidence to recommendation-determinants of a recommendation's direction and strength
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GRADE guidelines: 2. Framing the question and deciding on important outcomes.
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GRADE guidelines: 20. Assessing the certainty of evidence in the importance of outcomes or values and preferences—inconsistency, imprecision, and other domains
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GRADE guidelines: 21 part 1. Study design, risk of bias, and indirectness in rating the certainty across a body of evidence for test accuracy
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GRADE guidelines: 21 part 2. Test accuracy: inconsistency, imprecision, publication bias, and other domains for rating the certainty of evidence and presenting it in evidence profiles and summary of findings tables
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GRADE guidelines: 22. The GRADE approach for tests and strategies-from test accuracy to patient-important outcomes and recommendations.
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GRADE guidelines: 29. Rating the certainty in time-to-event outcomes - Study limitations due to censoring of participants with missing data in intervention studies
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GRADE guidelines: 3. Rating the quality of evidence
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GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
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scientific article (publication date: April 2011)
GRADE guidelines: 5. Rating the quality of evidence--publication bias
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GRADE guidelines: 7. Rating the quality of evidence--inconsistency
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GRADE guidelines: 8. Rating the quality of evidence--indirectness
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GRADE guidelines: 9. Rating up the quality of evidence
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GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology
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GRADE weak or conditional recommendations mandate shared decision-making. Author Response
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GRADE: Assessing the quality of evidence in environmental and occupational health
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GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
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GRADE: assessing the quality of evidence for diagnostic recommendations
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GRADE: assessing the quality of evidence for diagnostic recommendations
Gap Between Official Guidelines and Clinical Practice for the Treatment of Rheumatoid Arthritis in São Paulo, Brazil
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Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline
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Gender differences in grant and personnel award funding rates at the Canadian Institutes of Health Research based on research content area: A retrospective analysis
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General health checks are not beneficial for general adult population
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Generating health technology assessment evidence for rare diseases
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Generic and specific measurement of health-related quality of life in a clinical trial of respiratory rehabilitation
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Getting more out of meta-analyses: a new approach to meta-analysis in light of unexplained heterogeneity
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Getting research findings into practice: When to act on the evidence
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Glossary of evidence-based orthopaedic terminology.
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Glucagon-like peptide-1 receptor agonists and heart failure in type 2 diabetes: systematic review and meta-analysis of randomized and observational studies
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Goal attainment in a randomized controlled trial of rehabilitation after myocardial infarction
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Going from evidence to recommendations
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Grades of Recommendation for Antithrombotic Agents
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Grades of recommendation for antithrombotic agents
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Grades of recommendation for antithrombotic agents: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
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Grading quality of evidence and strength of recommendations
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Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
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Grading quality of evidence and strength of recommendations in clinical practice guidelines part 3 of 3. The GRADE approach to developing recommendations.
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Grading quality of evidence and strength of recommendations in clinical practice guidelines. Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventions
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Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies
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Grading strength of recommendations and quality of evidence in clinical guidelines: report from an american college of chest physicians task force
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Guideline conflict of interest management and methodology heavily impacts on the strength of recommendations: comparison between two iterations of the American College of Chest Physicians Antithrombotic Guidelines
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Guideline for opioid therapy and chronic noncancer pain
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Guideline group composition and group processes: article 3 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report
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Guideline of guidelines: thromboprophylaxis for urological surgery
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Guideline panels should not GRADE good practice statements
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Guideline panels should seldom make good practice statements: guidance from the GRADE Working Group
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Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise
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Guidelines for Health Technology Assessment
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Guidelines for anticoagulant use in acute coronary syndromes
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Guidelines for anticoagulant use in acute coronary syndromes – Authors' reply
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Guidelines for reading literature reviews.
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Guidelines for the clinical and economic assessment of health technologies: the case of magnetic resonance
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Guidelines for the clinical and economic evaluation of health care technologies
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Guidelines seek unbiased recommendations
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HLA-B8 and erythema nodosum
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Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches
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Health Utility Book (HUB)-Cancer: Protocol for a Systematic Literature Review of Health State Utility Values in Cancer
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Health issues and health care expenses in Canadian bankruptcies and insolvencies
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Health status assessment of the elderly
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Health status, quality of life, and the individual
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Health-Related Quality of Life and Participation in Osteoporosis Clinical Trials
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Health-Related Values and Preferences Regarding Meat Consumption: A Mixed-Methods Systematic Review
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Health-related quality of life following operative treatment of unstable ankle fractures: a prospective observational study
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Health-related quality of life in chronic liver disease: the impact of type and severity of disease
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Health-related quality of life in women with polycystic ovary syndrome, a self-administered questionnaire, was validated
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Helping Patients Integrate Research Evidence
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Helping Patients With Type 2 Diabetes Mellitus Make Treatment Decisions
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Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis
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Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial
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High statistical heterogeneity is more frequent in meta-analysis of continuous than binary outcomes
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High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome
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High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission
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Higher versus lower positive end-expiratory pressure in acute lung injury and acute respiratory distress syndrome: systematic review and individual patient data meta-analysis
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Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis
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Hip fracture evaluation with alternatives of total hip arthroplasty versus hemiarthroplasty (HEALTH): protocol for a multicentre randomised trial
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Home-monitoring of oral anticoagulation vs. dabigatran. An indirect comparison
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How a well-grounded minimal important difference can enhance transparency of labelling claims and improve interpretation of a patient reported outcome measure
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How can quality of life researchers make their work more useful to health workers and their patients?
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How do cancer screening guidelines trade off benefits versus harms and burdens of screening? A systematic survey
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How long is long enough for pharmacological thromboprophylaxis in urology?
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How many patients? How many limbs? Analysis of patients or limbs in the orthopaedic literature: a systematic review
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How should clinicians interpret results reflecting the effect of an intervention on composite endpoints: should I dump this lump?
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How should clinicians use the results of randomized trials?
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How should we measure function in patients with chronic heart and lung disease?
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How strong is the evidence for the use of perioperative beta blockers in non-cardiac surgery? Systematic review and meta-analysis of randomised controlled trials
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How strong is the evidence?
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How to Ascertain Drug Safety in the Context of Benefit. Controversies and Concerns
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How to Use a Randomized Clinical Trial Addressing a Surgical Procedure: Users' Guide to the Medical Literature
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How to appraise a diagnostic test
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How to do clinical practice research: a new book and a new series in the Journal of Clinical Epidemiology
How to generalize efficacy results of randomized trials: recommendations based on a systematic review of possible approaches
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How to keep up with the medical literature: I. Why try to keep up and how to get started
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How to keep up with the medical literature: II. Deciding which journals to read regularly
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How to keep up with the medical literature: III. Expanding the number of journals you read regularly
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How to keep up with the medical literature: IV. Using the literature to solve clinical problems
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How to keep up with the medical literature: V. Access by personal computer to the medical literature
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How to keep up with the medical literature: VI. How to store and retrieve articles worth keeping
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How to read a systematic review and meta-analysis and apply the results to patient care: users' guides to the medical literature
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How to spread information
How to teach evidence-based medicine to teachers: reflections from a workshop experience
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How to use a noninferiority trial: users' guides to the medical literature
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How to use a subgroup analysis: users' guide to the medical literature
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How to use an article about genetic association: A: Background concepts
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How to use an article about genetic association: B: Are the results of the study valid?
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How to use an article about genetic association: C: What are the results and will they help me in caring for my patients?
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How to use an article about prognosis
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How to use an article about quality improvement
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How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage
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How to use an article reporting a multiple treatment comparison meta-analysis
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How to use articles about diagnostic technology: gastric tonometry
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How to use diagnostic test articles in the intensive care unit: diagnosing weanability using f/Vt
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Human important outcomes and EBM during the COVID-19 pandemic
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Hypnosis/Relaxation therapy for temporomandibular disorders: a systematic review and meta-analysis of randomized controlled trials
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Identification of facilitators and barriers to home dialysis selection by canadian adults with ESRD.
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Identifying adults at risk of COPD who need confirmatory spirometry in primary care: Do symptom-based questions help?
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Immunotherapy improves health-related quality of life of adult patients with dermal reactions following yellow jacket stings
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Impact of liver transplantation on health-related quality of life
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Impact of maternal reproductive factors on cancer risks of offspring: A systematic review and meta-analysis of cohort studies
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Impact of missing participant data for dichotomous outcomes on pooled effect estimates in systematic reviews: a protocol for a methodological study
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Impact of pulmonary rehabilitation on psychosocial morbidity in patients with severe COPD
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Impact of quality of evidence on the strength of recommendations: an empirical study
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Implantable cardiac defibrillator and mortality in non-ischaemic cardiomyopathy: an updated meta-analysis
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Importance of evidence-based medicine on research and practice
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Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format
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Improving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments
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Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units
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In Raynaud phenomenon, on-demand sildenafil did not reduce disability or frequency or duration of attacks
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In Reply
In intermediate-risk acute PE, tenecteplase plus heparin reduced hemodynamic decompensation but increased stroke
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In localized prostate cancer, radical prostatectomy and observation did not differ for mortality at 13 years
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In patients receiving DAPT after coronary stents, the PRECISE-DAPT score predicted bleeding moderately well
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In patients with severe sepsis, hydrocortisone did not prevent progression to septic shock
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In severe aortic stenosis with intermediate surgical risk, TAVR was noninferior to SAVR for death or disabling stroke
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In the dark: the reporting of blinding status in randomized controlled trials
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In the era of systematic reviews, does the size of an individual trial still matter
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Inadequacy of intravenous heparin therapy in the initial management of venous thromboembolism
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Incidence and Remission of Nocturia: A Systematic Review and Meta-analysis
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Incidence of and Risk Factors for Ventilator-Associated Pneumonia in Critically Ill Patients
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Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature
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Incorporating Patient Preferences in Evidence-Based Medicine
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Incorporating considerations of resources use into grading recommendations
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Incorporating content related to value and cost-considerations in clinical decision-making: enhancements to medical education
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Incorporating multiple interventions in meta-analysis: an evaluation of the mixed treatment comparison with the adjusted indirect comparison
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Incretin Therapy and Risk of Pancreatitis in Type 2 Diabetes Mellitus: Systematic Review of Randomized and Non-Randomized Studies
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Incretin based treatments and mortality in patients with type 2 diabetes: systematic review and meta-analysis
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Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies
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Individual opioids, and long- versus short-acting opioids, for chronic noncancer pain: Protocol for a network meta-analysis of randomized controlled trials
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Individuals with diabetes preferred that future trials use patient-important outcomes and provide pragmatic inferences
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Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease.
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Influence of perceived functional and employment status on cardiopulmonary resuscitation directives
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Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design
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Insomnia and risk of mortality from all-cause, cardiovascular disease, and cancer: Systematic review and meta-analysis of prospective cohort studies
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Instruments to measure acceptability of information and acquisition of knowledge in patients with heart failure
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Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials
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Integrating research into clinical practice: challenges and solutions for Canada
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Integrating values and consumer involvement in guidelines with the patient at the center: article 8 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report
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Intention-to-treat principle
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Interaction of St John's wort with conventional drugs: systematic review of clinical trials
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Internal consistency reliability is a poor predictor of responsiveness
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Internal fixation compared with arthroplasty for displaced fractures of the femoral neck. A meta-analysis
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International approaches to the prescription of long-term oxygen therapy
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International law's effects on health and its social determinants: protocol for a systematic review, meta-analysis, and meta-regression analysis
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Internet versus mailed questionnaires: a controlled comparison (2).
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Internet versus mailed questionnaires: a randomized comparison (2).
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Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation
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Interobserver reliability of classification systems to rate the quality of femoral neck fracture reduction
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Interobserver variation in interpreting chest radiographs for the diagnosis of acute respiratory distress syndrome
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Interobserver variation in the computed tomographic evaluation of mediastinal lymph node size in patients with potentially resectable lung cancer. Canadian Lung Oncology Group
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Interpretation of rhinoconjunctivitis quality of life questionnaire data
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Interpretation of treatment changes in 6-minute walk distance in patients with COPD
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Interpreting Authorship Order and Corresponding Authorship
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Interpreting Results and Drawing Conclusions
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Interpreting changes in quality-of-life score in N of 1 randomized trials
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Interpreting small differences in functional status: the Six Minute Walk test in chronic lung disease patients
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Interpreting, integrating, and individualizing evidence about the prevention of diabetic nephropathy
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Interventions to enhance self management support
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Interventions to reduce unintended pregnancies among adolescents: systematic review of randomised controlled trials
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Interviewer versus self-administered questionnaires in developing a disease-specific, health-related quality of life instrument for asthma
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Introduction to BMJ Rapid Recommendations
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Introduction to a Series of Systematic Reviews of Weaning From Mechanical Ventilation
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Introduction to the ninth edition: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
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Iraq War mortality estimates: a systematic review
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Iron deficiency anemia in the elderly: the diagnostic process
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Is There Really A Controversy Surrounding the Effectiveness of Respiratory Rehabilitation in COPD?
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Isoniazid prophylaxis for tuberculosis in HIV infection: a meta-analysis of randomized controlled trials
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Italian version of Qualiveen-30: cultural adaptation of a neurogenic urinary disorder-specific instrument
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Jejunostomy tube feeding in patients undergoing esophagectomy
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Kappa statistic
Kidney Function Alters the Relationship between Postoperative Troponin T Level and Death
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LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact
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Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial
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Longer- Versus Shorter-Duration Dual-Antiplatelet Therapy After Drug-Eluting Stent Placement: A Systematic Review and Meta-analysis
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Low intensity pulsed ultrasonography for fractures: systematic review of randomised controlled trials
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Low intensity pulsed ultrasound for bone healing: systematic review of randomized controlled trials
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Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial.
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