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List of works by Gavin J. Wright

A Human Platelet Receptor Protein Microarray Identifies the High Affinity Immunoglobulin E Receptor Subunit α (FcεR1α) as an Activating Platelet Endothelium Aggregation Receptor 1 (PEAR1) Ligand

scientific article

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions

scientific article published on 23 December 2015

A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys

scientific article

A benchmarked protein microarray-based platform for the identification of novel low-affinity extracellular protein interactions

scientific article published on 17 February 2012

A cell surface interaction network of neural leucine-rich repeat receptors

scientific article

A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates

scientific article published on 26 April 2019

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

scientific article published on 10 November 2012

A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins

scientific article

A library of recombinant Babesia microti cell surface and secreted proteins for diagnostics discovery and reverse vaccinology

scientific article published on 24 October 2018

A panel of recombinant monoclonal antibodies against zebrafish neural receptors and secreted proteins suitable for wholemount immunostaining

scientific article

A panel of recombinant proteins from human-infective Plasmodium species for serological surveillance

scientific article published on 17 January 2020

A rapid and scalable method for selecting recombinant mouse monoclonal antibodies

scientific article

Alpha-v-containing integrins are host receptors for the sporozoite surface protein, TRAP

article published in the Proceedings of the National Academy of Sciences of the United States of America

Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against Plasmodium falciparum in Culture

scientific article published on 28 May 2019

Approaches to identify extracellular receptor–ligand interactions

scientific article published on 21 November 2018

Avidity-based extracellular interaction screening (AVEXIS) for the scalable detection of low-affinity extracellular receptor-ligand interactions

scientific article

Basigin is a druggable target for host-oriented antimalarial interventions

scientific article published on 20 July 2015

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants

scientific article (publication date: July 2016)

Biochemical analysis of the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction: implications for vaccine design

scientific article (publication date: 8 November 2013)

Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41

scientific article

CD200 and membrane protein interactions in the control of myeloid cells

scientific article

Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain

scientific article published on 02 May 2024

Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.

scientific article

Cloning of Recombinant Monoclonal Antibodies from Hybridomas in a Single Mammalian Expression Plasmid

scientific article published on 01 January 2014

Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling ⬇️

scientific article

Cross-species fertilization: the hamster egg receptor, Juno, binds the human sperm ligand, Izumo1.

scientific article

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development

scientific article

DeltaC and DeltaD interact as Notch ligands in the zebrafish segmentation clock

scientific article

Detecting Low-Affinity Extracellular Protein Interactions Using Protein Microarrays

scientific article published on 01 April 2013

Development of an antigen microarray for high throughput monoclonal antibody selection

scientific article published on 25 January 2014

Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals

scientific article

Divergent evolution of vitamin B9 binding underlies Juno-mediated adhesion of mammalian gametes

scientific article published on February 2016

Do muscle founder cells exist in vertebrates?

scientific article published on 16 June 2012

Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens ⬇️

scientific article

EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality

scientific article

Erratum: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

scientific article published in Nature Communications

Expression of recombinant ITGA2 and CD109 for the detection of human platelet antigen (HPA)-5 and -15 alloantibodies

scientific article published on 14 February 2013

Find and fuse: Unsolved mysteries in sperm-egg recognition

scientific article published on 13 November 2020

Genome-scale identification of cellular pathways required for cell surface recognition

scientific article published on 18 June 2018

Genomic Organisation, Embryonic Expression and Biochemical Interactions of the Zebrafish Junctional Adhesion Molecule Family of Receptors ⬇️

scientific article published on July 18, 2012

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

scientific article published on 22 August 2019

High-throughput identification of transient extracellular protein interactions

scientific article published on August 2010

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies

scientific article published on 13 June 2019

Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor

scientific article

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

scientific article published on 2 November 2017

Identifying novel Plasmodium falciparum erythrocyte invasion receptors using systematic extracellular protein interaction screens ⬇️

scientific article published on 13 May 2013

Important Extracellular Interactions between Plasmodium Sporozoites and Host Cells Required for Infection

scientific article published on 21 December 2018

Izumo meets Juno: preventing polyspermy in fertilization

scientific article published on 6 June 2014

Jamb and Jamc Are Essential for Vertebrate Myocyte Fusion ⬇️

scientific article published on December 13, 2011

Juno is the egg Izumo receptor and is essential for mammalian fertilization

scientific article

Large-scale screening for novel low-affinity extracellular protein interactions

scientific article

Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta

scientific journal article

Missense mutations in β-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome.

scientific article published on 28 January 2013

Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria

scientific article published on 16 October 2013

Neurexins, neuroligins and LRRTMs: synaptic adhesion getting fishy

scientific article

New antigens for a multicomponent blood-stage malaria vaccine

scientific article published in July 2014

P-selectin is a host receptor for Plasmodium MSP7 ligands

scientific article (publication date: 5 June 2015)

P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

scientific article (publication date: 10 February 2017)

Plasmodium falciparum erythrocyte invasion: combining function with immune evasion ⬇️

scientific article

Pooled extracellular receptor-ligand interaction screening using CRISPR activation

Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

scientific article (publication date: 14 October 2015)

Quantification of Plasmodium-host protein interactions on intact, unmodified erythrocytes by back-scattering interferometry

scientific article

RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum.

scientific article

Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of P. falciparum malaria in humans

scientific article published on 15 October 2019

Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes ⬇️

scientific article (publication date: February 2015)

Robust adaptive immune response against infection marked by low parasitemia in a murine model of sickle cell disease

scientific article published on 01 December 2018

Semaphorin-7A is an erythrocyte receptor for P. falciparum merozoite-specific TRAP homolog, MTRAP

scientific article (publication date: 2012)

Setting the tempo in development: an investigation of the zebrafish somite clock mechanism

scientific article published in June 2007

Signal initiation in biological systems: the properties and detection of transient extracellular protein interactions ⬇️

scientific article

Sperm Meets Egg: The Genetics of Mammalian Fertilization

scientific article published on 2 September 2016

Synergistic malaria vaccine combinations identified by systematic antigen screening

scientific article

Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection

scientific article published on 16 October 2019

TMEM95 is a sperm membrane protein essential for mammalian fertilization

scientific article published on 02 June 2020

The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm

scientific article published on 22 October 2015

The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site

scientific article published on 08 September 2020

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

scientific article

The challenges involved in elucidating the molecular basis of sperm-egg recognition in mammals and approaches to overcome them

scientific article

The impact of gene expression regulation on evolution of extracellular signaling pathways

scientific article

The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages

scientific article published on 01 August 1997

The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins

scientific article published on 29 June 2016

The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans

scientific article

Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library

scientific article

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