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List of works by Tilmann Weber

Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods

scientific article published in 2021

Antitumor astins originate from the fungal endophyte Cyanodermella asteris living within the medicinal plant Aster tataricus

scientific article published on 06 December 2019

Automating Cloning by Natural Transformation

scientific article published on 24 November 2020

Bioinformatics Tools for the Discovery of New Nonribosomal Peptides.

scientific article published on January 2016

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

scientific article published on 25 March 2015

CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

scientific article published in January 2018

CRISPR-Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes

scientific article published on 10 July 2020

CRISPR/Cas-based genome engineering in natural product discovery

scientific article published on 01 September 2019

CRISPy-web: An online resource to design sgRNAs for CRISPR applications.

scientific article

Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters

scientific article published on 15 September 2021

Complete Genome Sequences of 13 Bacillus subtilis Soil Isolates for Studying Secondary Metabolite Diversity

scientific article published on 09 January 2020

Computational Applications in Secondary Metabolite Discovery (CAiSMD): an online workshop

scientific article

Cyanodermella asteris sp. nov. (Ostropales) from the inflorescence axis of Aster tataricus ⬇️

scientific article published in 2017

Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001

scientific article published on 27 August 2019

Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260

scientific article published on 19 July 2021

Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family

scientific article published on 9 December 2021

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

scientific article

Draft genome sequence of Talaromyces islandicus ("Penicillium islandicum") WF-38-12, a neglected mold with significant biotechnological potential

scientific article published on 18 July 2015

Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.

scientific article published on 12 January 2016

Engineering of actinomycetes using CRISPR/Cas9 technologies.

scientific article

Engineering of cell factories for the production of natural products

scientific article published on 10 September 2019

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

scientific article published on 19 February 2018

Genome-Scale Metabolic Reconstruction of Actinomycetes for Antibiotics Production

scientific article published on 09 September 2018

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

scientific article published on 23 September 2019

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365.

scientific article published on 3 October 2015

Improved lanthipeptide detection and prediction for antiSMASH

scientific article

Introduction to the Special Issue "Bioinformatic tools and approaches for Synthetic Biology of natural products".

scientific article published on 2 June 2016

Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris: The anti-cancer bisanthraquinone skyrin

scientific article published on 21 June 2017

Long-Read Metagenome-Assembled Genomes Improve Identification of Novel Complete Biosynthetic Gene Clusters in a Complex Microbial Activated Sludge Ecosystem

scientific article published in 2022

Lysoquinone-TH1, a New Polyphenolic Tridecaketide Produced by Expressing the Lysolipin Minimal PKS II in Streptomyces albus ⬇️

scientific article published on 28 June 2018

MIBiG 2.0: a repository for biosynthetic gene clusters of known function

scientific article published on 01 January 2020

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

scientific article published on 18 November 2022

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

scientific article published on 9 December 2024

Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes

scientific article

Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites

scientific article published on 13 April 2016

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Omics and multi-omics approaches to study the biosynthesis of secondary metabolites in microorganisms

scientific article published on 12 April 2018

Pangenome analysis of Enterobacteria reveals richness of secondary metabolite gene clusters and their associated gene sets

scientific article published on 06 May 2022

Patscanui: an intuitive web interface for searching patterns in DNA and protein data.

scientific article published in July 2018

Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases ⬇️

scientific article published on October 29, 2012

Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII.

scientific article published on 16 February 2017

Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

scientific article published on 23 January 2020

Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters.

scientific article

Recent development of computational resources for new antibiotics discovery.

scientific article published on 16 November 2017

Sequence-based classification of type II polyketide synthase biosynthetic gene clusters for antiSMASH

scientific article published on 04 January 2019

Streptocollin, a Type IV Lanthipeptide Produced by Streptomyces collinus Tü 365.

scientific article

Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

scientific article published on 07 March 2019

The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery

scientific article published on 2 May 2017

The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

scientific article published in 2021

The Draft Whole-Genome Sequence of the Antibiotic Producer Empedobacter haloabium ATCC 31962 Provides Indications for Its Taxonomic Reclassification

scientific article published on 07 November 2019

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

article

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

scientific article published on 24 October 2016

The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum'). ⬇️

scientific article

The evolution of genome mining in microbes - a review.

scientific article

The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production.

scientific article published on 5 February 2016

Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites Production

scientific article published on 27 October 2017

Towards the sustainable discovery and development of new antibiotics

scientific article published in 2021

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

scientific article published on 6 May 2015

antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification

scientific article published on 28 April 2017

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

scientific article published on 01 July 2019

antiSMASH 6.0: improving cluster detection and comparison capabilities

scientific article published in 2021

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