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List of works by Tilmann Weber

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antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

scientific article published on 6 May 2015
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

scientific article published on 14 June 2011
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

scientific article published on 3 June 2013
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification

scientific article published on 28 April 2017
NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

scientific article
Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

scientific article
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

scientific article published on 01 July 2019
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

scientific article (publication date: 16 May 2007)
The evolution of genome mining in microbes - a review.

scientific article
CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

scientific article published on 25 March 2015
The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

scientific article published on 24 October 2016
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes

scientific article
Molecular analysis of the kirromycin biosynthetic gene cluster revealed beta-alanine as precursor of the pyridone moiety

scientific article
Characterization of the ‘pristinamycin supercluster’ of Streptomyces pristinaespiralis

scientific article published on October 15, 2010
MIBiG 2.0: a repository for biosynthetic gene clusters of known function

scientific article published on 01 January 2020
In silico tools for the analysis of antibiotic biosynthetic pathways

scientific article published on February 19, 2014
Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis.

scientific article published on 9 July 2005
Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases

scientific article published on October 29, 2012
The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production.

scientific article published on 5 February 2016
The Antibiotic Resistant Target Seeker (ARTS), an exploration engine for antibiotic cluster prioritization and novel drug target discovery

scientific article published on 2 May 2017
Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

scientific article
CRISPy-web: An online resource to design sgRNAs for CRISPR applications.

scientific article
Improved lanthipeptide detection and prediction for antiSMASH

scientific article
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

article
Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365.

scientific article published on 3 October 2015
Synthetic biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production

scientific article published on 21 April 2012
Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS

scientific article published on 01 April 2011
Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster

scientific article published on 24 May 2010
Reprogramming Acyl Carrier Protein Interactions of an Acyl-CoA Promiscuous trans-Acyltransferase

scientific article published on April 10, 2014
Module extension of a non-ribosomal peptide synthetase of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina

scientific article published in May 2008
Streptocollin, a Type IV Lanthipeptide Produced by Streptomyces collinus Tü 365.

scientific article
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters.

scientific article
Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites

scientific article published on April 13, 2016
The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.

scientific article published on 4 July 2013
Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII.

scientific article published on 16 February 2017
Differential proteomic analysis reveals novel links between primary metabolism and antibiotic production in Amycolatopsis balhimycina

scientific article published in April 2010
Omics and multi-omics approaches to study the biosynthesis of secondary metabolites in microorganisms

scientific article published on 12 April 2018
CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

scientific article published in January 2018
Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites Production

scientific article published on 27 October 2017
Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17(T) (=DSM 44213T) producing (S,S)-N,N'-ethylenediaminedisuccinic acid

scientific article
Complete genome sequence of the kirromycin producer Streptomyces collinus Tü 365 consisting of a linear chromosome and two linear plasmids

scientific article
The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum').

scientific article
The phosphopantetheinyl transferase KirP activates the ACP and PCP domains of the kirromycin NRPS/PKS of Streptomyces collinus Tü 365

scientific article published on 31 March 2011
Draft genome sequence of Talaromyces islandicus ("Penicillium islandicum") WF-38-12, a neglected mold with significant biotechnological potential

scientific article published on 18 July 2015
Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

scientific article published on 07 March 2019
Genome-scale metabolic representation of Amycolatopsis balhimycina

scientific article published on 6 February 2012
Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150.

scientific article published in March 2014
Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024, Producing the Lantibiotic NAI-107

scientific article published on 23 January 2014
The kirromycin gene cluster of Streptomyces collinus Tü 365 codes for an aspartate-alpha-decarboxylase, KirD, which is involved in the biosynthesis of the precursor beta-alanine

scientific article published on 17 July 2009

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