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List of works by Pep Charusanti

A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2

scientific article

An experimentally validated genome-scale metabolic reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228.

scientific article

An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92.

scientific article

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

scientific article published on 25 March 2015

Capsule deletion via a λ-Red knockout system perturbs biofilm formation and fimbriae expression in Klebsiella pneumoniae MGH 78578.

scientific article

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

scientific article

Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction ⬇️

scientific article

Genetic Basis of Growth Adaptation of Escherichia coli after Deletion of pgi, a Major Metabolic Gene ⬇️

scientific article published on November 4, 2010

Genome-scale metabolic reconstructions of multiple Escherichia coli strains highlight strain-specific adaptations to nutritional environments

scientific article

MS/MS networking guided analysis of molecule and gene cluster families.

scientific article published on 24 June 2013

Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes

scientific article

Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites

scientific article published on 13 April 2016

Microbial regulatory and metabolic networks.

scientific article published on 24 August 2007

Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC

scientific article published on 23 September 2015

Multiple-omic data analysis of Klebsiella pneumoniae MGH 78578 reveals its transcriptional architecture and regulatory features

scientific article (publication date: 29 November 2012)

Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models

scientific article

Reconciling a Salmonella enterica metabolic model with experimental data confirms that overexpression of the glyoxylate shunt can rescue a lethal ppc deletion mutant

scientific article

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

scientific article (publication date: 9 August 2016)

Studying Salmonellae and Yersiniae host-pathogen interactions using integrated 'omics and modeling

scientific article published on January 2013

Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites

scientific article

Systems biology definition of the core proteome of metabolism and expression is consistent with high-throughput data.

scientific article

Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations

scientific article published on 4 November 2015

The aldehyde dehydrogenase, AldA, is essential for L-1,2-propanediol utilization in laboratory-evolved Escherichia coli.

scientific article published on 4 November 2016

Understanding system dynamics of an adaptive enzyme network from globally profiled kinetic parameters.

scientific article published on 15 January 2014

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