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List of works by Barbara Stecca

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

scientific article published on 12 February 2009

Aberrant dipeptidyl peptidase IV (DPP IV/CD26) expression in human hepatocellular carcinoma

scientific article published on 01 August 1997

Alteration of DNA ploidy and cell nuclearity in human hepatocellular carcinoma associated with HBV infection

scientific article published on December 1996

Brain as a paradigm of organ growth: Hedgehog-Gli signaling in neural stem cells and brain tumors.

scientific article

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

scientific article published on April 2017

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

scientific article published on 17 January 2010

Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy

scientific article

Culture and isolation of melanoma-initiating cells.

scientific article published in February 2013

Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival

scientific article published on 29 June 2016

E3 ubiquitin ligase PARK2, an inhibitor of melanoma cell growth, is repressed by the oncogenic ERK1/2-ELK1 transcriptional axis

scientific article published on 16 September 2020

ERK5 is activated by oncogenic BRAF and promotes melanoma growth

scientific article published on 27 February 2018

Enzymatic cytochemistry, DNA ploidy and AgNOR quantitation in hepatocellular nodules of uncertain malignant potential in liver cirrhosis

scientific article published on 01 April 1996

Exome sequencing in primary melanoma identifies novel drivers of melanoma progression.

scientific article

Gcm1 expression defines three stages of chorio-allantoic interaction during placental development.

scientific article published in July 2002

HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells ⬇️

scientific article published on September 1, 2012

HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.

scientific article published on 29 May 2015

Hedgehog--Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer

scientific article published in February 2004

Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets

scientific article

Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites.

scientific article published on 19 February 2018

Impact of ERK5 on the Hallmarks of Cancer ⬇️

scientific article published on 21 March 2019

Impaired telomerase activity in uninfected haematopoietic progenitors in HIV-1-infected patients

scientific article published in June 1998

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

scholarly article

Interference with HH-GLI signaling inhibits prostate cancer

scientific article

KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth

scientific article

Luciferase Reporter Assays to Study Transcriptional Activity of Hedgehog Signaling in Normal and Cancer Cells.

scientific article published on January 2015

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

scholarly article

Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?

scientific article published on 17 August 2015

Role of Protein Kinases in Hedgehog Pathway Control and Implications for Cancer Therapy

scientific article published on 29 March 2019

Role of a Preorganized Scaffold Presenting Four Residues of a GM-3 Lactone Mimetic on Melanoma Progression. ⬇️

scientific article published on 10 November 2015

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.

scientific article

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

scientific article published on 17 November 2020

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

scientific article

Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors

Telomerase activity in touch-imprint cell preparations from fresh prostate needle biopsy specimens.

scientific article

The Gli code: an information nexus regulating cell fate, stemness and cancer.

scientific article

The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming

scientific article

The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway

scientific article

Thin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations.

scientific article published on 15 April 2016

Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cells

scientific article published on 25 January 2017

WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function.

scientific article published on 12 November 2012

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