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List of works by Stephen F Madden

5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.

scientific article published in November 2011

A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib

scientific article published on 22 July 2017

ADAM10: a new player in breast cancer progression?

scientific article

Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation

scientific article

BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome

scientific article published on January 2013

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression

scientific article published on 30 April 2015

Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients

scientific article published on 20 June 2015

Detecting microRNA activity from gene expression data

scientific article

Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.

scientific article

Digital extractor: analysis of digital differential display output.

scientific article

Distinct patterns in the regulation and evolution of human cancer genes

article

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

scientific article

Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours

scientific article

Expression of anaesthetic and analgesic drug target genes in excised breast tumour tissue: Association with clinical disease recurrence or metastasis

scientific article

Gene expression analysis in prostate cancer: the importance of the endogenous control.

scientific article published on 27 August 2012

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

scientific article

Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression.

scientific article published in March 2004

Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung

scientific article published on 8 August 2008

Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target?

scientific article

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.

scientific article published on 27 July 2017

Increase in sialylation and branching in the mouse serum N-glycome correlates with inflammation and ovarian tumour progression

scientific article (publication date: 2013)

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

scientific article published on November 21, 2012

Integrating transcription factor binding site information with gene expression datasets

scientific article published on 24 November 2006

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

scientific article (publication date: June 2011)

Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007.

scientific article

Neuromedin U: a candidate biomarker and therapeutic target to predict and overcome resistance to HER-tyrosine kinase inhibitors

scientific article

OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.

scientific article

Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells.

scientific article published on 15 February 2015

Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells

scientific article

Repuncturing the renal biopsy: strategies for molecular diagnosis in nephrology.

scientific article

Sustained Expression of Steroid Receptor Coactivator SRC-2/TIF-2 is Associated with Better Prognosis in Malignant Pleural Mesothelioma

scientific article published on January 1, 2012

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

scientific article

TGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation

scientific article

The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer

scientific article published on 20 October 2016

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation

scientific article

Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer

scientific article published on 28 April 2017

Tyrosine kinase inhibitors as modulators of trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity in breast cancer cell lines.

scientific article

Vitamin D receptor as a target for breast cancer therapy

scientific article published on 17 February 2017

miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in vitro

scientific article