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List of works by Thomas W Kensler

5,6-Epoxyretinoic acid opposes the effects of 12-O-tetradecanoylphorbol-13-acetate in bovine lymphocytes ⬇️

scientific article published on January 18, 1979

A facile tritium release assay for mammalian l-dihydroorotate dehydrogenase ⬇️

scientific article published on 01 November 1981

A straightforward method for the simultaneous preparation of radiolabeled l-dihydroörotic and N-carbamyl-l-aspartic acids ⬇️

scientific article published on 01 February 1981

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

scientific article published in PLoS ONE

Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model.

scientific article published on 19 September 2016

Aflatoxin regulations and global pistachio trade: insights from social network analysis.

scientific article

Aflatoxin: A 50-Year Odyssey of Mechanistic and Translational Toxicology ⬇️

scientific article published on September 29, 2010

Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway ⬇️

scientific article published on December 1, 2003

Author Correction: Nrf2 contributes to the weight gain of mice during space travel

scientific article published on 07 October 2020

Bioavailability of Sulforaphane from Two Broccoli Sprout Beverages: Results of a Short-term, Cross-over Clinical Trial in Qidong, China ⬇️

scientific article published on March 1, 2011

Biomarkers and Mechanistic Approaches in Environmental Epidemiology ⬇️

scientific article published on January 1, 1995

Cancer Prevention: Obstacles, Challenges and the Road Ahead.

scientific article

Changing rates for liver and lung cancers in Qidong, China

scientific article (publication date: 21 January 2014)

Chemoprevention by inducers of carcinogen detoxication enzymes ⬇️

scientific article published on June 1, 1997

Chemoprevention targets for tobacco-related head and neck cancer: past lessons and future directions

scientific article

Chemotherapeutic Inhibitors of the Enzymes of the de Novo Pyrimidine Pathway

scientific article published on January 1, 1981

Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.

scientific article

Crosstalk between Nrf2 and Notch signaling.

scientific article

Current Landscape of NRF2 Biomarkers in Clinical Trials

scientific article published on 07 August 2020

Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle

scientific article published on 2 February 2016

Effect of Green Tea Supplements on Liver Enzyme Elevation: Results from a Randomized Intervention Study in the United States

scientific article published in August 2017

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane

scientific article

Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity.

scientific article

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH.

scientific article published on 6 June 2017

Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice

scientific article

Global risk assessment of aflatoxins in maize and peanuts: are regulatory standards adequately protective?

scientific article published on 12 June 2013

Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development.

scientific article published on 14 December 2015

Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo

scientific article published on 8 March 2013

Identification of dithiolethione-inducible gene-1 as a leukotriene B4 12-hydroxydehydrogenase: implications for chemoprevention ⬇️

scientific article published on June 1, 1998

Inhibition of mitogenesis in bovine lymphocytes by juvenile hormones ⬇️

scientific article published on 01 February 1978

Inhibition of oxygen radical metabolism in phorbol ester-activated polymorphonuclear leukocytes by an antitumor promoting copper complex with superoxide dismutase-mimetic activity ⬇️

scientific article published on November 15, 1983

Inhibition of phorbol ester action in lymphocytes by 5,6-epoxy-β-ionone ⬇️

scientific article published on July 14, 1978

Inhibition of phorbol ester-accelerated amino acid transport in bovine lymphocytes ⬇️

scientific article published on June 1, 1979

Isothiocyanates: Translating the Power of Plants to People.

scientific article published on 21 February 2018

KEAP1 and Done? Targeting the NRF2 Pathway with Sulforaphane

scientific article published on 16 February 2017

Keap1 hypomorphism protects against ischemic and obstructive kidney disease

scientific article published on 2 November 2016

Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane

scientific article published on January 2013

Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.

scientific article published on 14 December 2015

Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism

scientific article

Levels of aflatoxin-albumin biomarkers in rat plasma are modulated by both long-term and transient interventions with oltipraz ⬇️

scientific article published on August 1, 1995

Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity

scientific article

Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage ⬇️

scientific article published on May 7, 2012

Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase

scientific article published on 22 July 2013

Molecular biomarkers for aflatoxins and their application to human liver cancer ⬇️

scientific article published on January 1, 1995

NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland

scientific article published on 01 June 2018

NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction

scientific article published on 17 April 2017

NRF2 as an Emerging Therapeutic Target.

scientific article published on 31 January 2017

NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

scientific article published on 26 February 2018

NRF2/long noncoding RNA ROR signaling regulates mammary stem cell expansion and protects against estrogen genotoxicity

scientific article

Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation ⬇️

scientific article published on July 30, 1998

Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

scientific article published on 2 May 2015

Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.

scientific article published on 02 December 2013

Notes from the Field: “Green” Chemoprevention as Frugal Medicine ⬇️

scientific article published on February 1, 2012

Nrf2 contributes to the weight gain of mice during space travel

scientific article published on 08 September 2020

Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance ⬇️

scientific article published on February 24, 2012

Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice.

scientific article published on 27 February 2018

Nrf2 in liver toxicology

scientific article published on 28 November 2019

Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.

scientific article published on 8 March 2018

Nrf2: control of sensitivity to carcinogens ⬇️

scientific article published on 03 March 2011

Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine ⬇️

scientific article published on February 16, 2012

Pharmacogenomics of chemically distinct classes of Keap1-Nrf2 activators identify common and unique gene, protein, and pathway responses in vivo

scientific article published on 24 January 2018

Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice

scientific article published on 04 November 2020

Predictive power of hepatitis B 1762T/1764A mutations in plasma for hepatocellular carcinoma risk in Qidong, China ⬇️

scientific article published on April 7, 2011

Present and future directions of translational research on aflatoxin and hepatocellular carcinoma. A review ⬇️

scientific article published on January 1, 2012

Profound changes in miRNA expression during cancer initiation by aflatoxin B1 and their abrogation by the chemopreventive triterpenoid CDDO-Im

scientific article published on 20 February 2017

Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the Gastrointestinal Microflora ⬇️

scientific article published on February 7, 2012

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer

scientific article published on 26 January 2018

Redox Regulation of Genes that Protect Against Carcinogens ⬇️

scientific article published on November 1, 1997

Reduced foodborne toxin exposure is a benefit of improving dietary diversity

scientific article

Serum miR-182 is a predictive biomarker for dichotomization of risk of hepatocellular carcinoma in rats

scientific article published on 02 August 2019

Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol

scientific article published on 30 July 2020

Synergistic effect of 5-fluorouracil and N-(phosphonacetyl)-l-aspartate on cell growth and ribonucleic acid synthesis in a human mammary carcinoma ⬇️

scientific article published on 01 August 1981

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

scientific article published on 01 July 2018

The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice.

scientific article published on 02 October 2013

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells ⬇️

scientific article published on May 5, 2011

Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2 ⬇️

scientific article published on January 4, 2011

Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles ⬇️

scientific article published on May 20, 2011

Transforming Cancer Prevention through Precision Medicine and Immune-oncology.

scientific article published on January 2016

Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro ⬇️

scientific article published on 01 July 1997

Use of aflatoxin adducts as intermediate endpoints to assess the efficacy of chemopreventive interventions in animals and man ⬇️

scientific article published on June 18, 1998

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system ⬇️

scientific article published on June 23, 2012

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

scientific article published on 4 October 2016

“MAPping” the Course of Chemoprevention in Breast Cancer ⬇️

scientific article published on 04 June 2011

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