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List of works by Kevin P. Bateman

'All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching

scientific article published in January 2005

16th Annual Land O'Lakes Bioanalytical Conference

scientific article published on 13 November 2015

2012 white paper on recent issues in bioanalysis and alignment of multiple guidelines

scientific article published on 01 September 2012

A strategy for identification of drug metabolites from dried blood spots using triple-quadrupole/linear ion trap hybrid mass spectrometry

scientific article published on 01 January 2005

An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.

scientific article published on 08 February 2016

Antibiotic resistance in Streptomyces lividans: fluorescence assay for streptogramin B lyase

scientific article published on 01 June 1997

Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK.

scientific article

Boston Society's 7th Applied Pharmaceutical Analysis

scientific article published on 01 January 2012

Comparison of MALDI to ESI on a triple quadrupole platform for pharmacokinetic analyses.

scientific article

Coupling of Uhplc With Fast Fraction Collection–Microplate Scintillation Counting And Ms For Radiolabeled Metabolite Profiling ⬇️

scientific article published on June 1, 2012

Desaturation index versus isotopically measured de novo lipogenesis as an indicator of acute systemic lipogenesis

scientific article

Detection of covalent adducts to cytochrome P450 3A4 using liquid chromatography mass spectrometry

scientific article published on 01 October 2004

Development of generic liquid chromatography-mass spectrometry methods using experimental design ⬇️

scientific article published on January 1, 2002

Direct comparison of radioimmunoassay and LC-MS/MS for PK assessment of insulin glargine in clinical development.

scientific article published on January 2014

Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524)

scientific article published on 01 February 2007

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.

scientific article published on 15 September 2005

Discovery stage pharmacokinetics using dried blood spots

scientific article published on 01 September 2004

Fractional mass filtering as a means to assess circulating metabolites in early human clinical studies

scientific article published on 01 November 2008

Generic automated method for liquid chromatography-multiple reaction monitoring mass spectrometry based monoclonal antibody quantitation for preclinical pharmacokinetic studies.

scientific article published on 14 August 2014

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry

scientific article

IQ consortium perspective: complementary LBA and LC-MS in protein therapeutics bioanalysis and biotransformation assessment

scientific article published on 25 February 2020

Impacting biology through analysis

scientific article published on 01 April 2010

Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studies

scientific article published on 19 August 2017

Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective

scientific article published on 15 September 2020

Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560

scientific article published on 01 June 2006

MSE with mass defect filtering for in vitro and in vivo metabolite identification

scientific article published on 01 January 2007

Mass spectral analyses of microcystins from toxic cyanobacteria using on-line chromatographic and electrophoretic separations

scientific article published on 01 September 1995

Merck's perspective on the implementation of dried blood spot technology in clinical drug development - why, when and how

scientific article published on 01 February 2013

Metabolic activation of indole-containing prostaglandin D2 receptor 1 antagonists: impacts of glutathione trapping and glucuronide conjugation on covalent binding

scientific article published on 23 March 2007

Novel cytochrome P450-mediated ring opening of the 1,3,4-oxadiazole in setileuton, a 5-lipoxygenase inhibitor.

scientific article

Organic chemistry. Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

scientific article published on 20 November 2014

Phosphopeptide isomer separation using capillary zone electrophoresis for the study of protein kinases and phosphatases

scientific article published on 01 August 1999

Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors.

scientific article published on 5 June 2011

Probing the substrate specificity of an enzyme catalyzing inactivation of streptogramin B antibiotics using LC-MS and LC-MS/MS ⬇️

scientific article published on October 1, 1997

Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry

scientific article published on 29 December 2015

Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer

scientific article

Rapid measurement of deuterium-labeled long-chain fatty acids in plasma by HPLC-ESI-MS

scientific article published on 04 October 2006

Simultaneous analysis of prostanoids using liquid chromatography/high-field asymmetric waveform ion mobility spectrometry/tandem mass spectrometry

scientific article published on 01 January 2006

The development of patient-centric sampling as an enabling technology for clinical trials

scientific article published on 06 July 2020

Using miniature MS system with automatic blood sampler for preclinical pharmacokinetics study.

scientific article published on 2 November 2017

Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A.

scientific article published on 10 December 2016

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