List of works - Chiara Falciani

A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin

scientific article published on 01 August 2002

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs

scientific article

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

scientific article

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

scientific article published on 16 November 2009

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

scientific article published on 20 November 2019

Antimicrobial Peptide-Loaded Nanoparticles as Inhalation Therapy for Pseudomonas aeruginosa Infections

scientific article published on 17 February 2020

Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification

scientific article

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

scientific article published on 05 June 2019

Bioactive peptides from libraries.

scientific article

Branched peptides as novel tumor-targeting agents for bladder cancer

scientific article published on 01 June 2012

Branched peptides as therapeutics

scientific article

Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity.

scientific article

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

scientific article published on 6 July 2017

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

scientific article published in April 2010

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

scientific article published on 8 October 2011

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

scientific article published on 07 October 2016

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

scientific article published on 12 May 2016

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

scientific article

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

scientific article published on 2 June 2017

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

scientific article

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

scientific article

Molecular basis of branched peptides resistance to enzyme proteolysis

scientific article published on 01 March 2007

Molecular definition of the interaction between a tumor-specific tetrabranched peptide and LRP6 receptor

scientific article published on 17 June 2020

NMR and MD studies on the interaction between ligand peptides and alpha-bungarotoxin.

scientific article

Nanoparticles exposing neurotensin tumor-specific drivers.

scientific article published on 25 February 2013

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

scientific article published on 3 March 2018

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

scientific article published on 23 April 2015

Oligo-branched peptides for tumor targeting: from magic bullets to magic forks

scientific article published on 01 February 2009

Phthalimidesulfenyl Chloride.(1) 11. Generation, General Reactivity, and Synthetic Applications of o-Thioquinones

scientific article published on 01 April 1997

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

scientific article published on 08 February 2014

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

scientific article

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

scientific article

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

scientific article published on 8 February 2017

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

scientific article published on 31 August 2007

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

scientific article published on 02 March 2011

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

scientific article

The development of antimicrobial peptides as new antibacterial drugs.

scientific article published on December 2013

Tumor imaging with tetrabranched neurotensin.

scientific article published in January 2009

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

scientific article

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

scientific article published on 18 September 2019

List of works by Chiara Falciani

A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

Antimicrobial Peptide-Loaded Nanoparticles as Inhalation Therapy for Pseudomonas aeruginosa Infections

Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

Bioactive peptides from libraries.

Branched peptides as novel tumor-targeting agents for bladder cancer

Branched peptides as therapeutics

Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity.

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

Molecular basis of branched peptides resistance to enzyme proteolysis

Molecular definition of the interaction between a tumor-specific tetrabranched peptide and LRP6 receptor

NMR and MD studies on the interaction between ligand peptides and alpha-bungarotoxin.

Nanoparticles exposing neurotensin tumor-specific drivers.

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

Oligo-branched peptides for tumor targeting: from magic bullets to magic forks

Phthalimidesulfenyl Chloride.(1) 11. Generation, General Reactivity, and Synthetic Applications of o-Thioquinones

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

The development of antimicrobial peptides as new antibacterial drugs.

Tumor imaging with tetrabranched neurotensin.

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity