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List of works by Matthew J Wongchenko

A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia

scientific article published on 08 March 2016

A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types.

scientific article published on 7 March 2018

Activating alleles of JAK3 in acute megakaryoblastic leukemia

scientific article published on July 2006

Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2

scientific article

Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition

scientific article

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

scientific article

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.

scientific article published on 12 February 2018

Association of programmed death ligand-1 (PD-L1) expression with treatment outcomes in patients with BRAF mutation-positive melanoma treated with vemurafenib or cobimetinib combined with vemurafenib.

scientific article published on 20 November 2017

Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients

scientific article published on 06 June 2019

Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial

scientific article published on 29 July 2016

Concordance between plasma-based and tissue-based next-generation sequencing in LOTUS.

scientific article published on 31 October 2017

Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma

scientific article published on 10 January 2019

Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.

scientific article published on 18 October 2013

Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma

scientific article published on 15 November 2019

Gene Expression Profiling in BRAF-Mutated Melanoma Reveals Patient Subgroups with Poor Outcomes to Vemurafenib That May Be Overcome by Cobimetinib Plus Vemurafenib

scientific article

Genomic Features of Exceptional Response in Vemurafenib ± Cobimetinib-treated Patients with BRAF V600-mutated Metastatic Melanoma

scientific article published on 01 March 2019

HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.

scientific article

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

scientific article published on 15 January 2018

Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

scientific article published on 8 August 2017

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies

scientific article published on 11 April 2011

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

scientific article published on 24 July 2017

The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs

scientific article published on 28 June 2019

Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation

scientific article published on 01 March 2019

Transcriptional subtypes resolve tumor heterogeneity and identify vulnerabilities to MEK inhibition in lung adenocarcinoma

scientific article published on 06 October 2020

Tumour gene expression signature in primary melanoma predicts long-term outcomes

scientific article published on 18 February 2021

bcGST-an interactive bias-correction method to identify over-represented gene-sets in boutique arrays

scientific article published on 01 April 2019

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