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List of works by Ellis J Neufeld

A Budget Impact Model of Hemophilia Bypassing Agent Prophylaxis Relative to Recombinant Factor VIIa On-Demand

scientific article

A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent β-Thalassemia

scientific article published on 01 March 2020

A mutant fibroblast cell line defective in glycoprotein synthesis due to a deficiency of glucosamine phosphate acetyltransferase

scientific article published on 01 June 1978

A phase 1 dose-escalation study: safety, tolerability, and pharmacokinetics of FBS0701, a novel oral iron chelator for the treatment of transfusional iron overload.

scientific article

A phase 2 study of the safety, tolerability, and pharmacodynamics of FBS0701, a novel oral iron chelator, in transfusional iron overload

scientific article published on 17 January 2012

ARMS test for diagnosis of factor VLeiden mutation, a common cause of inherited thrombotic tendency

scientific article published on 01 January 1996

Applicability of 2009 international consensus terminology and criteria for immune thrombocytopenia to a clinical pediatric population

scientific article

Assessment of individual dose utilization vs. physician prescribing recommendations for recombinant activated factor VII (rFVIIa) in paediatric and adult patients with congenital haemophilia and alloantibody inhibitors (CHwI): the Dosing Observation

scientific article

Author's response: 'Transition considerations for extended half-life factor products'.

scientific article published on 4 May 2015

Beliefs about chelation among thalassemia patients

scientific article published on 7 December 2012

Bioengineering hemophilia A-specific microvascular grafts for delivery of full-length factor VIII into the bloodstream

scientific article published on 01 December 2019

Bleeding manifestations and management of children with persistent and chronic immune thrombocytopenia: data from the Intercontinental Cooperative ITP Study Group (ICIS).

scientific article

Bleeding risks are higher in children versus adults given prophylactic platelet transfusions for treatment-induced hypoproliferative thrombocytopenia

scientific article

Blockade of selectin-mediated leukocyte adhesion improves postischemic function in lamb hearts

scientific article published on 01 November 1996

CSF 5-Methyltetrahydrofolate Serial Monitoring to Guide Treatment of Congenital Folate Malabsorption Due to Proton-Coupled Folate Transporter (PCFT) Deficiency

scientific article

Center-Based Quality Initiative Targets Youth Preparedness for Medical Independence: HEMO-Milestones Tool in a Comprehensive Hemophilia Clinic Setting

scientific article

Characterization of a murine high-affinity thiamine transporter, Slc19a2.

scientific article

Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort ⬇️

scientific article published on January 25, 2012

Chronic disseminated intravascular coagulation and childhood-onset skin necrosis resulting from homozygosity for a protein C Gla domain mutation, Arg15Trp

scientific article published in November 2002

Clinical Impact of an Anticoagulation Screening Service at a Pediatric Tertiary Care Facility

Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases

scientific article published on 01 April 2007

Clinical outcomes in a cohort of patients with heparin-induced thrombocytopenia

scientific article

Coagulation abnormalities in patients with single-ventricle physiology precede the Fontan procedure

scientific article published in March 2002

Combined schedule of 7-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal vaccine in children and young adults with sickle cell disease

scientific article published on 01 August 1998

Comorbidities and complications in adults with pyruvate kinase deficiency

scientific article published on 28 December 2020

Compliance with immunizations in splenectomized individuals with hereditary spherocytosis

scientific article published on 01 July 2009

Complications of beta-thalassemia major in North America

scientific article published on 26 February 2004

Correlation between dispensed and prescribed doses of factor products for bleeding disorders: can a small, centre-based pharmacy hit the mark?

scientific article

Corticosteroids for acute chest syndrome in children with sickle cell disease: variation in use and association with length of stay and readmission.

scientific article published in January 2010

Cost analysis of plasma-derived factor VIII/von Willebrand factor vs recombinant factor VIII for treatment of previously untreated patients with severe hemophilia A in the United States.

scientific article published on 21 April 2018

Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).

scientific article published on 31 July 2003

Deferasirox pharmacokinetics in patients with adequate versus inadequate response

scientific article published on September 2009

Does iron overload really matter in stem cell transplantation?

scientific article

Dosing, efficacy, and safety of recombinant factor VIIa (rFVIIa) in pediatric versus adult patients: the experience of the Hemostasis and Thrombosis Research Society (HTRS) Registry (2004-2008).

scientific article

Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia

scientific article

Education and employment status of children and adults with thalassemia in North America

scientific article

Effect of acute bleeding on daily quality of life assessments in patients with congenital hemophilia with inhibitors and their families: observations from the dosing observational study in hemophilia

scientific article

Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial ⬇️

scientific article published on May 10, 2003

Erythrocyte pyruvate kinase deficiency: 2015 status report

scientific article

Evaluation of the coagulation system in children with two-ventricle congenital heart disease

scientific article published on 01 May 2007

Exposure and safety of higher doses of recombinant factor VIIa ≥250 μg kg−1 in individuals with congenital haemophilia complicated by alloantibody inhibitors: the Haemophilia and Thrombosis Research Society Registry experience (2004-2008) ⬇️

scientific article published on February 7, 2011

Extracorporeal membrane oxygenation as a bridge to cardiac transplantation in a patient with cardiomyopathy and hemophilia A ⬇️

scientific article published on April 29, 2003

Female monozygotic twins discordant for hemophilia A due to nonrandom X-chromosome inactivation.

scientific article

Focusing in on use of pharmacokinetic profiles in routine hemophilia care

scientific article published on 27 May 2018

Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility

scientific journal article

Genetic studies in pediatric ITP: outlook, feasibility, and requirements

scientific article

Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort

scientific article published in April 2015

Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications

scientific article

Hemoglobin Jamaica plain--a sickling hemoglobin with reduced oxygen affinity.

scientific article published in October 2004

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

scientific article

Hemophilia. A new approach to an old disease.

scientific article

Hormonal contraception and thrombotic risk: a multidisciplinary approach.

scientific article

Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

scientific article published on April 1, 1992

Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients

scientific article published on 12 March 2013

Human T-cell lymphotropic virus type 1 infection among U.S. Thalassemia patients.

scientific article published on 7 January 2014

Immunogenicity, efficacy and safety of Nuwiq(®) (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study

scientific article

Impact of acute bleeding on daily activities of patients with congenital hemophilia with inhibitors and their caregivers and families: observations from the Dosing Observational Study in Hemophilia (DOSE).

scientific article published on 14 August 2014

Inadequate dietary intake in patients with thalassemia

scientific article

Increased leucocyte apoptosis in transfused β‐thalassaemia patients ⬇️

scientific article published on December 6, 2012

Increasing observation rates in low-risk pediatric immune thrombocytopenia using a standardized clinical assessment and management plan (SCAMP® ).

scientific article

Induced pluripotent stem cells with a mitochondrial DNA deletion

scientific article published on July 2013

Infantile myofibroma or lymphatic malformation: differential diagnosis of neonatal cystic cervicofacial lesions

scientific article published on 01 March 2010

Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial

scientific article published on 10 May 2008

Inflammatory bowel disease associated with immune thrombocytopenic purpura in children.

scientific article

Iron chelation adherence to deferoxamine and deferasirox in thalassemia

scientific article

Iron overload in patients with acute leukemia or MDS undergoing myeloablative stem cell transplantation.

scientific article published on 18 September 2010

Liver MRI is more precise than liver biopsy for assessing total body iron balance: a comparison of MRI relaxometry with simulated liver biopsy results.

scientific article published on 20 February 2015

MRI guided iron assessment and oral chelator use improve iron status in thalassemia major patients.

scientific article published on 10 April 2014

Male infertility and thiamine-dependent erythroid hypoplasia in mice lacking thiamine transporter Slc19a2.

scientific article published in September 2003

Myocardial immediate early gene activation after cardiopulmonary bypass with cardiac ischemia-reperfusion

scientific article published on 01 January 2002

Nonfasting low-density lipoprotein testing: utility for cholesterol screening in pediatric primary care

scientific article published in June 2007

Novel dominant β-thalassemia: Hb Boston-Kuwait [codon 139/140(+T)].

scientific article published on 15 June 2013

Observational cohort study of pediatric inpatients with central venous catheters at "intermediate risk" of thrombosis and eligible for anticoagulant prophylaxis.

scientific article published on 23 July 2010

One year follow-up of children and adolescents with chronic immune thrombocytopenic purpura (ITP) treated with rituximab

scientific article

Oral chelation: should it be used with young children?

scientific article published on October 2010

Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions

scientific article

Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia ⬇️

scientific article published on May 7, 2012

P-selectin expression in myocardium of children undergoing cardiopulmonary bypass

scientific article published on 01 October 1995

Pain as an emergent issue in thalassemia

scientific article published in May 2010

Pediatric heparin-induced thrombocytopenia: prevalence, thrombotic risk, and application of the 4Ts scoring system

scientific article

Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations

scientific article published on 20 May 2018

Perioperative management of haemophilia B: A critical appraisal of the evidence and current practices

scientific article

Physician Decision Making in Selection of Second-Line Treatments in Immune Thrombocytopenia in Children.

scientific article published on 16 April 2018

Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP.

scientific article

Practical implications of liver and heart iron load assessment by T2*-MRI in children and adults with transfusion-dependent anemias

scientific article published in October 2008

Pre-transplantation iron chelation in patients with MDS or acute leukemia and iron overload undergoing myeloablative allo-SCT.

scientific article published on 21 May 2012

Preface to Cooley's Anemia: Ninth Symposium

scientific article

Pregnancy outcomes in women with thalassemia in North America and the United Kingdom

scientific article

Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study

scientific article published on 13 September 2018

Prevalence of the metabolic syndrome in American adolescents: findings from the Third National Health and Nutrition Examination Survey.

scientific article

Primary care clinicians' knowledge and confidence about newborn screening for sickle cell disease: randomized assessment of educational strategies.

scientific article published in August 2010

Production of phosphoinositide-derived messengers

scientific article published on 01 July 1984

Prospective longitudinal study of coagulation profiles in children with hypoplastic left heart syndrome from stage I through Fontan completion

scientific article published on 23 February 2009

Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura

scientific article

Prospective reevaluation of the association between thrombotic diathesis and legg-perthes disease

scientific article published on 01 September 2002

R2 and R2* are equally effective in evaluating chronic response to iron chelation.

scientific article

Recognizing the need for personalization of haemophilia patient-reported outcomes in the prophylaxis era.

scientific article

Recombinant porcine factor VIII for high-risk surgery in paediatric congenital haemophilia A with high-titre inhibitor

scientific article published on 25 January 2017

Red cell alloimmunization in a diverse population of transfused patients with thalassaemia ⬇️

scientific article published on February 17, 2011

Refractory autoimmune disease: an overview of when first-line therapy is not enough

scientific article published on 07 April 2016

Regional variation and cost implications of prescribed extended half-life factor concentrates among U.S. Haemophilia Treatment Centres for patients with moderate and severe haemophilia

scientific article published on 17 April 2019

Relationship among chelator adherence, change in chelators, and quality of life in thalassemia

scientific article

Relationship between chronic transfusion therapy and body composition in subjects with thalassemia

scientific article

Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study

scientific article

Remission from transfusion-dependence in a patient with congenital dyserythropoietic anemia (CDA) and increased intensity of iron chelation.

scientific article published in December 2009

Renal dysfunction in patients with thalassaemia ⬇️

scientific article published on February 21, 2011

Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.

scientific article published on May 1995

Response to mercaptopurine for refractory autoimmune cytopenias in children

scientific article

Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia

scientific article

Response: What's in a name?

scientific article published in October 2007

Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter

scientific article

Ringed sideroblasts in β-thalassemia

scientific article published on 3 November 2016

Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report ⬇️

scientific article published on July 19, 2011

Risk factors for thromboembolism in teens: when should I test?

scientific article

Risk of post-procedural bleeding in children on intravenous fish oil.

scientific article published on December 2016

Rituximab for treatment of inhibitors in haemophilia A. A Phase II study.

scientific article published on 12 June 2014

Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia

scientific article published on 12 June 2008

Safety and efficacy of recombinant factor VIIa by pediatric age cohort: reassessment of compassionate use and trial data supporting US label.

scientific article

Safety and pharmacokinetics of the oral iron chelator SP-420 in β-thalassemia.

scientific article published on 22 September 2017

Safety of recombinant activated factor VII (rFVIIa) in patients with congenital haemophilia with inhibitors: overall rFVIIa exposure and intervals following high (>240 μg kg⁻¹) rFVIIa doses across clinical trials and registries.

scientific article published in January 2014

Safety update on the use of recombinant activated factor VII in approved indications.

scientific article published on June 2015

Screening and counseling for thalassemia

scientific article published on February 2006

Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes

scientific article published on 29 April 2019

Sequence-specific binding of HMG-I (Y) to the proximal promoter of the gp91-phox gene

scientific article published on 01 January 1993

Severe haemophilia A in a female resulting from two de novo factor VIII mutations.

scientific article published in August 1995

Severe hemorrhage in children with newly diagnosed immune thrombocytopenic purpura

scientific article

Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

scientific article published on 12 April 2013

Skin testing, graded challenge, and desensitization to von Willebrand factor (VWF) products in type III von Willebrand disease (VWD).

scientific article published on 9 July 2016

Sports Participation in Children and Adolescents with Immune Thrombocytopenia (ITP).

scientific article

Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia

scientific article

Symptoms of depression and anxiety in patients with thalassemia: prevalence and correlates in the thalassemia longitudinal cohort.

scientific article

Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations

scientific article

Targeted ITP strategies: do they elucidate the biology of ITP and related disorders?

scientific article

The clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study

scientific article published on 16 March 2018

The frequency and management of asparaginase‐related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana‐Farber Cancer Institute consortium protocols ⬇️

scientific article published on January 7, 2011

The incidence and implications of anti-heparin-platelet factor 4 antibody formation in a pediatric cardiac surgical population

scientific article

The use of erythropoietin-stimulating agents versus supportive care in newborns with hereditary spherocytosis: a single centre's experience

scientific article

Thiamine-responsive megaloblastic anemia: identification of novel compound heterozygotes and mutation update

scientific article

Thirty-day readmission rates following hospitalization for pediatric sickle cell crisis at freestanding children's hospitals: risk factors and hospital variation

scientific article

Time course of early induction of intracellular adhesion molecule-1 messenger RNA during reperfusion, following cardiopulmonary bypass with hypothermic circulatory arrest in lambs

scientific article published in January 2003

To treat or not to treat--from guidelines to individualized patient management.

scientific article

Tracking the impact of the National Institutes of Health Clinical and Translational Science Awards on child health research: developing and evaluating a measurement strategy.

scientific article published on February 2012

Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME).

scientific article published on 25 July 2013

Transition considerations for extended half-life factor products.

scientific article published on 9 April 2015

Transition from pediatric to adult care for sickle cell disease: results of a survey of pediatric providers

scientific article

Treatment and outcomes of immune cytopenias following solid organ transplant in children

scientific article

Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone

scientific article published on 20 May 2013

Treatment with rituximab in benign and malignant hematologic disorders in children

scientific article

Trends in anti-D immune globulin for childhood immune thrombocytopenia: usage, response rates, and adverse effects

scientific article

Unrelated Donor Transplantation in Children with Thalassemia Using Reduced Intensity Conditioning - the URTH Trial.

scientific article published on 25 January 2018

Update on genetic risk factors for thrombosis and atherosclerotic vascular disease

scientific article published on 01 December 1998

Update on iron chelators in thalassemia

scientific article

Urinary hepcidin in congenital chronic anemias

scientific article

Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major

scientific article

Validity, reliability, and responsiveness of a new measure of health-related quality of life in children with immune thrombocytopenic purpura: the Kids' ITP Tools.

scientific article

X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation

scientific article

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