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List of works by Sylvie Doublié

8-oxoguanine DNA glycosylases: one lesion, three subfamilies

scientific article

A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex

scientific article

A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation

scientific article (publication date: November 2014)

An open and closed case for all polymerases.

scientific article

Base Excision Repair in the Mitochondria.

scientific article

Cryocooling of Macromolecular Crystals: Optimization Methods

scientific article published on 01 January 2003

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution ⬇️

scientific article published on January 15, 1998

Crystallization and preliminary X-ray analysis of the 9 kDa protein of the mouse signal recognition particle and the selenomethionyl-SRP9

scientific article published on 01 April 1996

Crystallization and preliminary crystallographic analysis of the signal recognition particle SRPphi14-9 fusion protein

scientific article published on 01 April 1996

Crystallographic software: a sustainable resource for the community

scientific article published on 01 January 2007

DNA polymerase θ (POLQ), double-strand break repair, and cancer

scientific article

Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity

scientific article

Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase

scientific article

Determinants of substrate specificity in RNA-dependent nucleotidyl transferases

scientific article published on 14 December 2007

Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).

scientific article published on 24 May 2017

Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection.

scientific article

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair

scientific article

Infidelity out in the open

scientific article published on 01 October 2004

Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69

scientific article

Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.

scientific article

Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor

scientific article

Mechanism of suppression of chromosomal instability by DNA polymerase POLQ

scientific article (publication date: October 2014)

Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage ⬇️

scientific article published on December 26, 2012

Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.

scientific article published on 4 July 2004

Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage

scientific article

Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase.

scientific article

Preparation of selenomethionyl proteins for phase determination

scientific article (publication date: 1997)

Purification, crystallization and preliminary X-ray diffraction of a disulfide cross-linked complex between bovine poly(A) polymerase and a chemically modified 15-mer oligo(A) RNA.

scientific article published on 22 January 2011

Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β.

scientific article

Structural Characterization of Clostridium acetobutylicum 8-Oxoguanine DNA Glycosylase in Its Apo Form and in Complex with 8-Oxodeoxyguanosine

scientific article

Structural Studies of a Bacterial tRNAHIS Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites

scientific article

Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family

scientific article

Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.

scientific article published on 05 August 2004

Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing

scientific article

Structural biology of poly(A) site definition

scientific article (publication date: 2011)

Structural insights into eukaryotic DNA replication

scientific article

The A-Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ.

scientific article

The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction

scientific article

The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage

scientific article

The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site

scientific article

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.

scientific article published on 8 September 2017

The mechanism of action of T7 DNA polymerase

scientific article published on 01 December 1998

tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases

scientific article

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