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List of works by Thomas J. Hannan

A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131.

scientific article published on 03 June 2013

A Murine Model for Escherichia coli Urinary Tract Infection

scientific article

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease.

scientific article

Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections

scientific article published on 30 September 2016

Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection

scientific article

Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections

scientific article published on March 2017

Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection.

scientific article

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism

scientific article

Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections.

scientific article published on February 2016

Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection

scientific article

Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection ⬇️

scientific article published on August 12, 2010

Enterococcus faecalis Overcomes Foreign Body-Mediated Inflammation To Establish Urinary Tract Infections ⬇️

scientific article published on November 6, 2012

Estrogen and recurrent UTI: what are the facts?

scientific article published on 01 June 2013

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.

scientific article

Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner

scientific article published on 13 December 2018

Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection

scientific article published on May 2012

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.

scientific article published on 24 October 2014

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

scientific article published on 20 August 2019

Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection

scientific article published on 30 April 2015

Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity

scientific article published on 31 March 2015

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