Search filters

List of works by Erwan Mortier

Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor.

scientific article

Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation

scientific article published on 16 November 2010

Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization

scientific article

Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data

scientific article

Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles

scientific article published on 30 May 2018

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

scientific article published on 11 February 2008

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

scientific article published on 22 December 2008

IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells

scientific article

IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

scientific article published on 5 May 2008

IL-15Rα membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling

scientific article published on 05 December 2019

Identification of an interleukin-15alpha receptor-binding site on human interleukin-15

scientific article (publication date: 4 June 2004)

Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease

scientific article published on 23 February 2010

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

scientific article

Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets

scientific article published on 12 November 2009

Mechanistic and Structural Insights on the IL-15 System through Molecular Dynamics Simulations

scientific article published on 06 September 2019

NK Cell Hyporesponsiveness: More Is Not Always Better

scientific article published on 12 September 2019

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist

scientific article

Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering

scientific article published on 6 November 2013

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins

scientific article

Syndecan-1 regulates the biological activities of interleukin-34.

scientific article

The Soluble Chain of Interleukin-15 Receptor: A Proinflammatory Molecule Associated with Tumor Progression in Head and Neck Cancer

scientific article published on 01 May 2008

The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha

scientific article

[Cut the cord, you're ready to set off on your own!]

scientific article published on 14 October 2014

[Interleukin 2 revival: a revisited model and new therapeutic applications]

scientific article published on 01 June 2016

Paulina is supported by:

About Paulina

Help