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List of works by Toni-Kim Clarke

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

scientific article published on 02 May 2016

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A meta-analysis of genome-wide association studies of epigenetic age acceleration

scientific article published on 18 November 2019

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

scientific article published on 08 May 2020

A validation of the diathesis-stress model for depression in Generation Scotland

article

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

scientific article published in Nature Communications

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An Intronic Variant in OPRD1 Predicts Treatment Outcome for Opioid Dependence in African-Americans.

scientific article published on 12 February 2014

An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population

scientific article

An intronic variant in OPRD1 predicts treatment outcome for opioid dependence in African-Americans

scientific article

Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data.

scientific article

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

scientific article published on 18 December 2017

Association study of the β-arrestin 2 gene (ARRB2) with opioid and cocaine dependence in a European-American population

scientific article published on June 2012

Author Correction: Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

scientific article published on 01 March 2019

Case-control association analysis of polymorphisms in the δ-opioid receptor, OPRD1, with cocaine and opioid addicted populations

scientific article

Characterization of genetic variation in the VGLL4 gene in anorexia nervosa

scientific article

Cognitive functioning and lifetime major depressive disorder in UK Biobank

scientific article published on 21 February 2020

Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): a questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS).

scientific article published on 18 July 2017

Dissection of major depressive disorder using polygenic risk scores for schizophrenia in two independent cohorts.

scientific article

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

scientific article published on 15 August 2017

Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking

scientific article published on 9 August 2011

Epigenetic prediction of major depressive disorder

scientific article published on 10 June 2020

Epigenetic signatures of starting and stopping smoking

scientific article published on 30 October 2018

Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target

scientific article published on 02 December 2021

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium

scientific article

Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

scientific article published on 04 February 2020

Factors associated with sharing e-mail information and mental health survey participation in large population cohorts

scientific article published on 01 July 2019

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis

scientific article published on 25 July 2011

Gene-environment interactions resulting in risk alcohol drinking behaviour are mediated by CRF and CRF1.

scientific article published on 03 May 2009

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis

scientific article

Genetic and environmental contributions to psychological resilience and coping

Genetic and environmental determinants of stress responding ⬇️

scientific article published on January 1, 2012

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

scientific article published on 01 January 2018

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

article

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

scientific article published on 25 November 2019

Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.

scientific article published on 11 April 2012

Genetic effects influencing risk for major depressive disorder in China and Europe

scientific article

Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition

scientific article published on 02 October 2019

Genetic stratification of depression in UK Biobank

scientific article published on 24 May 2020

Genetic variation in OPRD1 and the response to treatment for opioid dependence with buprenorphine in European-American females.

scientific article published on 15 October 2013

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts

scientific article published on 19 October 2018

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

article

Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

scientific article published on 16 December 2016

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117)

article

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).

scientific article published on 25 July 2017

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

article

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.

scientific article published on 16 April 2018

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

article

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.

scientific article published on 30 November 2017

Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.

scientific article published on 10 January 2018

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

scientific article published on 04 February 2019

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.: Supplementary Information

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Global genetic variations predict brain response to faces

scientific article

HPA-axis activity in alcoholism: examples for a gene-environment interaction

scientific article published on 02 October 2007

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

scientific article published on 10 August 2017

Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank

scientific article published on 22 April 2019

Insulin resistance: Genetic associations with depression and cognition in population based cohorts

scientific article published on 06 April 2019

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

scientific article published on 02 August 2016

KCNJ6 is associated with adult alcohol dependence and involved in gene × early life stress interactions in adolescent alcohol drinking

scientific article

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Life after recovery: Increased resolution of forest resilience assessment sheds new light on post‐drought compensatory growth and recovery dynamics

scientific article published in 2021

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

scientific article

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

scientific article published on 30 June 2015

Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse

scientific article published on 11 November 2010

Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans

scientific article published on 20 September 2012

OPRD1 Genetic Variation and Human Disease.

scientific article published on 30 December 2016

Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study

scientific article published on 27 February 2019

Pharmacogenetics of Opioid Use Disorder Treatment

scientific article published on 01 April 2018

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

scientific article

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults

scientific article published on 28 January 2016

Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study.

scientific article published on 25 October 2017

Risk and protective factors for structural brain ageing in the eighth decade of life.

scientific article published on 19 April 2017

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

scientific article published on 18 July 2019

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

scientific article

The Genetics of Anorexia Nervosa

article

The Stratification Of Major Depressive Disorder Into Genetic Subgroups

scholarly article published 5 May 2017

The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction

scientific article

The evolution of the vertebrate metzincins; insights from Ciona intestinalis and Danio rerio

scientific article published on 17 April 2007

The genetics of alcoholism

scientific article published on October 2009

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scholarly article published 10 March 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

αCaMKII controls the establishment of cocaine's reinforcing effects in mice and humans.

scientific article

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