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List of works by Nicholas S. Duesbery

A human/murine chimeric fab antibody neutralizes anthrax lethal toxin in vitro.

scientific article published on 5 June 2013

A tribute to George F. Vande Woude, a man of character: 2006 Scientific Symposium Winning the War against Cancer: from Genomics to Bedside and Back.

scientific article published on 8 March 2007

Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia

scientific article published on 19 January 2016

Anthrax fusion protein therapy of cancer

scientific article

Anthrax lethal factor causes proteolytic inactivation of mitogen-activated protein kinase kinase

scientific article

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

scientific article

Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor

scientific article

Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage

scientific article published on 23 December 2007

Anthrax toxins.

scientific article

Anthrax, MEK and cancer.

scientific article

Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase

scientific article

BRAF and MEK mutations make a late entrance

scientific article published on 28 March 2006

BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin

scientific article published on September 2005

Biological and biochemical characterization of anthrax lethal factor, a proteolytic inhibitor of MEK signaling pathways.

scientific article published in January 2008

CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II.

scientific article published on August 1997

Cancer: biology and therapeutics--a tribute to George Vande Woude

scientific article

Changes in protein association with intracellular membranes of Xenopus laevis oocytes during maturation and activation

scientific article published in May 1993

Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes.

scientific article published in May 2002

Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

scientific article published on 6 May 2015

Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.

scientific article

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

scientific article published on 01 October 1998

Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells

scientific article published on May 2008

Developmental biology: an arresting activity.

scientific article

Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes

scientific article published in July 2005

Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous.

scientific article published on 3 October 2013

Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo.

scientific article published in January 2008

Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma

scientific article

Involvement of domain II in toxicity of anthrax lethal factor.

scientific article

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin

scientific article

MEK genomics in development and disease

scientific article

MEK wars, a new front in the battle against cancer

scientific article published on 01 July 1999

MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.

scientific article

MKK signaling and vascularization.

scientific article published on February 2007

Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis

scientific article published on April 2009

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

scientific article published on 15 March 2015

Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma

scientific article

Novel Protein Targeted Therapy of Metastatic Melanoma ⬇️

scientific article published on January 1, 2003

Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations

scientific article

Origins of cancer

scientific article published on 01 December 2008

Pathophysiology of anthrax

scientific article published on January 2009

Persistent inhibition of oxygen-induced retinal neovascularization by anthrax lethal toxin.

scientific article published on 21 November 2011

Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.

scientific article

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

scientific article published on 26 June 2013

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: implications for broad anti-tumor efficacy

scientific article published on 18 January 2008

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

scientific article

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha

scientific article

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

scientific article published on 06 September 2018

Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways

scholarly article

Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice ⬇️

scientific article published on 01 December 2006

The role of Ca(2+) in progesterone-induced germinal vesicle breakdown of Xenopus laevis oocytes: the synergic effects of microtubule depolymerization and Ca(2+).

scientific article published in September 1996

The role of microtubules and inositol triphosphate induced Ca2+ release in the tyrosine phosphorylation of mitogen-activated protein kinase in extracts of Xenopus laevis oocytes.

scientific article published in February 1996

The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution.

scientific article

Xenopus tropicalis oocytes: more than just a beautiful genome

scientific article

Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.

scientific article

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