List of works by Stuart MacGowan

A unified analysis of evolutionary and population constraint in protein domains highlights structural features and pathogenic sites

scientific article published in 2024

Ankyrin repeats in context with human population variation

scientific article published on 24 August 2021

Classification of likely functional class for ligand binding sites identified from fragment screening

scientific article published in 2024

Computational quantification of the physicochemical effects of heme distortion: redox control in the reaction center cytochrome subunit of Blastochloris viridis.

scientific article published on 15 January 2013

Conformational control of cofactors in nature - the influence of protein-induced macrocycle distortion on the biological function of tetrapyrroles

scientific article published on 01 December 2015

Contribution of bacteriochlorophyll conformation to the distribution of site-energies in the FMO protein.

scientific article published on 3 February 2016

Disease related single point mutations alter the global dynamics of a tetratricopeptide (TPR) α-solenoid domain

scientific article published on 16 October 2019

Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations

scientific article

Human Missense Variation is Constrained by Domain Structure and Highlights Functional and Pathogenic Residues

scholarly article published 12 April 2017

Missense variants in ACE2 are predicted to encourage and inhibit interaction with SARS-CoV-2 Spike and contribute to genetic risk in COVID-19

scientific article published on 05 May 2020

Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants

scientific article published on 02 March 2022

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.

scientific article published on 24 January 2018

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

scientific article

The Dundee Resource for Sequence Analysis and Structure Prediction

scientific article published on 28 November 2019

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