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List of works by Michelle D Leach

Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity

scientific article published on 2 November 2016

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States

scientific article

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.

scientific article

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

scientific article

Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans.

scientific article published on 5 January 2011

Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance.

scientific article

Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rsp5, and Hsf1 in Candida albicans.

scientific article published on 20 June 2014

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans

scientific article

Opportunistic yeast pathogens: reservoirs, virulence mechanisms, and therapeutic strategies

scientific article

Posttranslational modifications of proteins in the pathobiology of medically relevant fungi

scientific article

Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals.

scientific article published on 8 October 2009

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues.

scientific article

Stress adaptation in a pathogenic fungus

scientific article published on January 2014

Surviving the Heat of the Moment: A Fungal Pathogens Perspective ⬇️

scientific article published on March 7, 2013

The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans.

scientific article

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