List of works - Patrick M Collins

A Multi-Crystal Method for Extracting Obscured Signal from Crystallographic Electron Density

article published in 2016

A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

scientific article

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

scientific article (publication date: 24 April 2017)

A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03115j.

scientific article published on 22 December 2015

Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening

scientific article published on 15 October 2018

An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides.

scientific article published on 5 August 2015

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches ⬇️

scientific article

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

scientific article

Galectin-3 inhibitors: a patent review (2008-present).

scientific article

Galectin-3 interactions with glycosphingolipids

scientific article

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

scientific article

Gentle, fast and effective crystal soaking by acoustic dispensing

article published in 2016

Gentle, fast and effective crystal soaking by acoustic dispensing.

scientific article

Identification of a capsular polysaccharide from Moraxella bovis

scientific article published on 01 March 2005

Identification of a novel glycosyltransferase involved in LOS biosynthesis of Moraxella catarrhalis.

scientific article published on 24 August 2006

Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors

scientific article published on 22 July 2013

Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols

scientific article

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin

scientific article

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

scientific article published on 23 February 2018

Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping

scientific article published on 01 June 2019

Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks. ⬇️

scientific article published on 6 October 2017

Taloside inhibitors of galectin-1 and galectin-3

scientific article

The Low-Cost, Semi-Automated Shifter Microscope Stage Transforms Speed and Robustness of Manual Protein Crystal Harvesting

article published in 2019

The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.

scientific article

The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting

scientific article published on 01 January 2021

Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide

scientific article

List of works by Patrick M Collins

A Multi-Crystal Method for Extracting Obscured Signal from Crystallographic Electron Density

A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03115j.

Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening

An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides.

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches ⬇️

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

Galectin-3 inhibitors: a patent review (2008-present).

Galectin-3 interactions with glycosphingolipids

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

Gentle, fast and effective crystal soaking by acoustic dispensing

Gentle, fast and effective crystal soaking by acoustic dispensing.

Identification of a capsular polysaccharide from Moraxella bovis

Identification of a novel glycosyltransferase involved in LOS biosynthesis of Moraxella catarrhalis.

Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors

Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping

Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks. ⬇️

Taloside inhibitors of galectin-1 and galectin-3

The Low-Cost, Semi-Automated Shifter Microscope Stage Transforms Speed and Robustness of Manual Protein Crystal Harvesting

The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.

The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting

Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide