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List of works by Per-Olof Berggren

17β-Estradiol suppresses visceral adipogenesis and activates brown adipose tissue-specific gene expression

scientific article published on 10 November 2016

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A SIRTain role in pancreatic beta cell function

scientific article published in August 2005

A key role for phosphorylated inositol compounds in pancreatic beta-cell stimulus-secretion coupling

scientific article published on 14 March 2008

A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations

scientific article published in July 2005

ARA290 improves insulin release and glucose tolerance in type 2 diabetic GK rats

scientific article published on 29 December 2015

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell

scientific article

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells

scientific article published in December 2004

Accumulation of cadmium in pancreatic beta cells is similar to that of calcium in being stimulated by both glucose and high potassium

scientific article

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells

scientific article published in Nature

Activation of protein kinase C assists insulin producing cells in recovery from raised cytoplasmic Ca2+ by stimulating Ca2+ efflux

scientific article

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

scientific article

Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity.

scientific article

Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function

scientific journal article

Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).

scientific article

Adipsin is an adipokine that improves β cell function in diabetes

scientific article

Agonistic aptamer to the insulin receptor leads to biased signaling and functional selectivity through allosteric modulation

scientific article

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

scientific article

Alpha2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic ?-cells

scientific article published on 01 June 1991

Amounts and distribution of intracellular magnesium and calcium in pancreatic beta-cells

scientific article published on 01 February 1982

An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function

scientific article

An autocrine insulin feedback loop maintains pancreatic beta-cell 3-phosphorylated inositol lipids

scientific article

Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats

scientific article

Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src.

scientific article published on 15 August 2013

Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

scientific article published on 4 May 2015

Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes

scholarly article

Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase

scientific article published on 14 May 2015

Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion

scientific article published in November 2007

Assembly of functionalized silk together with cells to obtain proliferative 3D cultures integrated in a network of ECM-like microfibers

article

Automated, high-throughput assays for evaluation of human pancreatic islet function

scientific article published on January 2008

Beta-cell CaV channel regulation in physiology and pathophysiology

scientific article

Biochemical profiling of diabetes disease progression by multivariate vibrational microspectroscopy of the pancreas

scientific article published on 27 July 2017

Blocking Ca2+ Channel β3 Subunit Reverses Diabetes.

scientific article

C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy

scientific article published on 11 February 2013

CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice

scientific article published on 18 April 2014

Ca(2+)-induced Ca2+ release in insulin-secreting cells

scientific article

Ca2+ and pancreatic B-cell function

scientific article

Ca2+ transport in pancreatic beta-cells during glucose stimulation of insulin secretion.

scientific article

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum

scientific article published on 8 October 2014

CaV2.3 channel and PKClambda: new players in insulin secretion

scientific article

Cadmium-induced insulin release does not involve changes in intracellular handling of calcium

scientific article published on 01 June 1987

Calcium and pancreatic beta-cell function. IX. Demonstration of lanthanide-induced inhibition of insulin secretion independent of modifications in transmembrane Ca2+ fluxes

scientific article

Calcium and pancreatic β-cell function XI. Modification of 45Ca fluxes by Na+ removal

scientific article published on 01 October 1980

Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells

scientific article

Calcium movements in relation to glucose-stimulated insulin secretion

scientific article published on 01 January 1980

Calcium, magnesium, and zinc contents in organelles of prostatic origin in human seminal plasma

scientific article

Cell signaling by the type IV pili of pathogenic Neisseria.

scientific article

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

scientific article

Characterization of serine/threonine protein phosphatases in RINm5F insulinoma cells

scientific article published on 01 December 1993

Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic beta-cells

scientific article published on December 1987

Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15.

scientific article published on August 1991

Cholinergic augmentation of insulin release requires ankyrin-B.

scientific article published on 16 March 2010

Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents

scientific article

Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis

scientific article

Control of insulin secretion by cholinergic signaling in the human pancreatic islet

scientific article

Corrigendum to 'Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells' [Cellular Signalling 46 (2018) 120-128].

scientific article

Cyclic ADP-ribose and pancreatic beta cells

scientific article published on 01 December 1993

Cyclic ADP-ribose and the pancreatic beta cell: where do we stand? ⬇️

scientific article published on December 1, 1997

Cyclic ADP-ribose in beta cells

scientific article published on 01 October 1993

Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis

scientific journal article

Cyclin-dependent kinase 5 promotes insulin exocytosis.

scientific article published on 6 July 2001

Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis

scientific article

Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells

scientific article published on August 1992

Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca2+ concentration

scientific article published on 8 September 2003

DARPP-32 and inhibitor-1 are expressed in pancreatic beta-cells

scientific article published in April 2005

Delayed Ca2+ response to glucose in diabetic GK rat.

scientific article published on October 1997

Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells

scientific article

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells

scientific article published on 01 February 1993

Diabetes Prevention Through Antiviral Treatment in Biobreeding Rats

scientific article published on 9 August 2016

Diabetes is not associated with a change in the elemental composition of the pancreatic B cell in diabetic C57BL KsJ-db/db mice

scientific article published on 01 April 1990

Diet-induced β-cell insulin resistance results in reversible loss of functional β-cell mass.

scientific article

Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands

scientific article published on 17 October 2013

Dihydroxyacetone-induced oscillations in cytoplasmic free Ca2+ and the ATP/ADP ratio in pancreatic beta-cells at substimulatory glucose

scientific article published on 12 August 2003

Diphosphoinositol pentakisphosphate as a novel mediator of insulin exocytosis

scientific article published on January 2009

Diphosphosinositol polyphosphates and energy metabolism: assay for ATP/ADP ratio

scientific article published on January 2010

Direct determination of manganese in microgram amounts of pancreatic tissue by electrothermal atomic absorption spectrometry

scientific article published in August 1982

Direct evidence for opposite effects of D-glucose and D-glyceraldehyde on cytoplasmic pH of mouse pancreatic ?-cells

article

Direct inhibition of the pancreatic beta-cell ATP-regulated potassium channel by alpha-ketoisocaproate

scientific article published on 01 June 1998

Direct measurements of increased free cytoplasmic Ca2+ in mouse pancreatic beta-cells following stimulation by hypoglycemic sulfonylureas

scientific article

Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets

scientific article

Dissociation between exocytosis and Ca(2+)-channel activity in mouse pancreatic beta-cells stimulated with calmidazolium (compound R24571).

scientific article published on August 1995

Distribution of intraportally implanted microspheres and fluorescent islets in mice

scientific article published in January 2007

Does galanin inhibit insulin secretion by opening of the ATP-regulated K+ channel in the beta-cell?

scientific article

Donor islet endothelial cells in pancreatic islet revascularization

scientific article

Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts

scientific article published in August 2005

Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and Is responsible for the decreased activity in epithelial cells

scientific article published on January 1999

Down-regulated expression of exocytotic proteins in pancreatic islets of diabetic GK rats

scientific article published in March 2002

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth

scientific article published in December 2006

Dual effect of glucose on cytoplasmic free Ca2+ concentration and insulin release reflects the beta-cell being deprived of fuel

scientific article

Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells

scientific article

Effects of caffeine on cytoplasmic free Ca2+ concentration in pancreatic beta-cells are mediated by interaction with ATP-sensitive K+ channels and L-type voltage-gated Ca2+ channels but not the ryanodine receptor

scientific article published on March 1995

Effects of dietary inorganic trivalent chromium (Cr3+) on the development of glucose homeostasis in rats

scientific article published on 01 March 1989

Effects of glucose on the calcium content of intact beta-cells and cellular organelles

scientific article published on 01 January 1981

Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells

scientific article published on November 1989

Electrical bursting in islet ß cells

scientific article published in Nature

Electrical short-circuit in β-cells from a patient with non-insulinoma pancreatogenous hypoglycemic syndrome (NIPHS): a case report

scientific article published on 23 September 2010

Elemental composition in the pancreatic B cell is normal in the prediabetic Chinese hamster

scientific article published on 01 January 1992

Emodin regulates glucose utilization by activating AMP-activated protein kinase

scientific article published on 9 January 2013

Endogenous chromium in tissues and body fluids of normal and genetically diabetic (db/db) mice

scientific article published on 01 March 1985

Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity

scientific article published on October 1993

Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action

scientific article

Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes

scientific article

Evidence for Ca(2+)-regulated ATP release in gastrointestinal stromal tumors

scientific article published on 13 March 2013

Evidence for a Unique Long Chain Acyl-CoA Ester Binding Site on the ATP-regulated Potassium Channel in Mouse Pancreatic Beta Cells

scientific article published in Journal of Biological Chemistry

Evidence for divergent glucose effects on calcium metabolism in pancreatic beta- and alpha 2-cells

scientific article

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

scientific article published in May 1998

Expression of K channels in Xenopus laevis oocytes injected with poly(A+ ) mRNA from the insulin-secreting β-cell line, HIT T15

scientific article published on 01 November 1988

Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues.

scientific article

Expression of voltage-gated K+ channels in insulin-producing cells. Analysis by polymerase chain reaction

scientific article

Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

scientific article published on January 1990

Extracellular ATP mobilizes intracellular Ca2+ in T51B rat liver epithelial cells: a study involving single cell measurements

scientific article published on 01 March 1989

Extracellular Ca2+ induces a rapid increase in cytoplasmic free Ca2+ in pancreatic beta-cells

scientific article published on 01 November 1987

Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels

scientific article

Failure of glucose tolerance factor-containing Brewer's yeast to ameliorate spontaneous diabetes in C57BL/KsJ DB/DB mice

scientific article published in March 1989

Fluorescence-activated cell sorted rat islet cells and studies of the insulin secretory process

scientific article published on 01 April 1996

Galanin and the endocrine pancreas

scientific article published on March 1988

Galanin inhibits glucose-stimulated insulin release by a mechanism involving hyperpolarization and lowering of cytoplasmic free Ca2+ concentration

scientific article published on 01 November 1986

Galparan: a powerful insulin-releasing chimeric peptide acting at a novel site

scientific article published on August 1997

Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis

scientific article published on 8 April 2003

Glucagon regulates its own synthesis by autocrine signaling

scientific article

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors

scientific journal article

Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice

scientific article published on 01 October 1992

Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice

scientific article published on 01 May 1990

Glucose in glucagon release

scientific article published in April 1990

Glucose inhibition of 45Ca efflux from pancreatic islets

scientific article published on August 1978

Glucose intolerance and pancreatic β-cell dysfunction in the anorectic anx/anx mouse

scientific article published on 30 June 2015

Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells

scientific article

Glucose-induced changes in cytoplasmic free Ca2+ concentration and the significance for the regulation of insulin release. Measurements with fura-2 in suspensions and single aggregates of mouse pancreatic beta-cells

scientific article published on January 1989

Glucose-induced increase in cytoplasmic pH in pancreatic beta-cells is mediated by Na+/H+ exchange, an effect not dependent on protein kinase C

scientific article published on 01 December 1991

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior

scientific article published on 31 July 2001

Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell.

scientific article published on 9 July 2001

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

scientific article

Glucose-stimulated efflux of fura-2 in pancreatic beta-cells is prevented by probenecid

scientific article

Glucose-stimulated efflux of indo-1 from pancreatic beta-cells is reduced by probenecid

scientific article published on October 1990

Glucose-stimulated increase in cytoplasmic pH precedes increase in free Ca2+ in pancreatic beta-cells. A possible role for pyruvate

scientific article published on 01 May 1994

Glutamate is a positive autocrine signal for glucagon release

scientific article published on June 2008

Growth hormone promotes Ca(2+)-induced Ca2+ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation

scientific article published on 31 March 2004

HPLC separation of inositol polyphosphates

scientific article published on January 2010

Heparin inhibits IP3-induced Ca2+ release in permeabilized pancreatic beta-cells

scientific article published on 01 February 1988

Heparin inhibits inositol trisphosphate-induced calcium release from permeabilized rat liver cells

scientific article published on 01 December 1987

High-resolution, noninvasive longitudinal live imaging of immune responses ⬇️

scientific article

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

scientific article published in December 2016

Human interleukin 1 beta stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling.

scientific article

Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells

scientific article

Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery

scientific article published on 01 November 1996

Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP

scientific article published on 01 July 1996

Implantation site-dependent dysfunction of transplanted pancreatic islets

scientific article

In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.

scientific article published on May 1998

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.

scientific article

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.

scientific article published in April 1987

Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways

scientific article published on 19 December 2017

Inhibition of L-type calcium channels by internal GTP [?S] in mouse pancreatic ? cells

scientific article published on 01 January 1992

Inhibition of glucose-stimulated insulin release by alpha 2-adrenoceptor activation is parallelled by both a repolarization and a reduction in cytoplasmic free Ca2+ concentration

scientific article published in Journal of Biological Chemistry

Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells

scientific article published on 01 August 1995

Inhibition of serine/threonine protein phosphatases promotes opening of voltage-activated L-type Ca2+ channels in insulin-secreting cells

scientific article published on March 1994

Innervation patterns of autonomic axons in the human endocrine pancreas

scientific article

Inositol hexakisphosphate increases L-type Ca2+ channel activity by stimulation of adenylyl cyclase

scientific article

Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells

scientific article published on 6 March 2018

Inositol hexakisphosphate promotes dynamin I- mediated endocytosis ⬇️

scientific article

Inositol hexakisphosphate stimulates non-Ca2+-mediated and primes Ca2+-mediated exocytosis of insulin by activation of protein kinase C

scientific article

Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron

scientific article

Inositol pyrophosphates: structure, enzymology and function

scientific article published on 28 August 2009

Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells

scientific article published on October 1991

Insulin antibody production in guinea pigs is accompanied by disturbances in pancreatic islet morphology and glucagon secretion

scientific article

Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose

scientific article published on 01 August 1996

Insulin feedback action on pancreatic beta-cell function

scientific article

Insulin modulates the frequency of Ca2+ oscillations in mouse pancreatic islets

scientific article published on 28 August 2017

Insulin signaling in the pancreatic beta-cell

scientific article published on January 2008

Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion

scientific article published on 8 January 2010

Insulin-like growth factor II inhibits glucose-induced insulin exocytosis

scientific article published on 01 February 1998

Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells

scientific article

Insulinotropic activity of the imidazoline derivative RX871024 in the diabetic GK rat.

scientific article published in January 2002

Insulinotropic compounds decrease endothelial cell survival

scientific article

Interaction with the inositol 1,4,5-trisphosphate receptor promotes Ca2+ sequestration in permeabilised insulin-secreting cells

scientific article published on August 1991

Interactions between magnesium and calcium in beta-cell-rich pancreatic islets.

scientific article published on June 1983

Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model

scientific article published in August 2007

Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation

scientific article published on 01 June 1995

Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action

scientific article published on September 2010

Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells

scientific article published on October 1992

Intraocular in vivo imaging of pancreatic islet cell physiology/pathology

scientific article published on 4 May 2017

Intravital imaging of cytotoxic T lymphocytes

scientific article published in January 2014

Involvement of protein kinase C-epsilon in inositol hexakisphosphate-induced exocytosis in mouse pancreatic beta-cells

scientific journal article

Ionic mechanisms in pancreatic β cell signaling

scientific article

Isoform-specific insulin receptor signaling involves different plasma membrane domains.

scientific article

Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes

scientific article published on 29 September 2017

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

scientific article published in February 2018

Lipotoxicity and decreased islet graft survival

scientific article

Liraglutide Compromises Pancreatic β Cell Function in a Humanized Mouse Model

scientific article

Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging

scientific article

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel

scientific article published in November 1998

Lowering apolipoprotein CIII delays onset of type 1 diabetes

scientific article

Manganese accumulation in pancreatic beta-cells and its stimulation by glucose

scientific article

Markedly decreased blood perfusion of pancreatic islets transplanted intraportally into the liver: disruption of islet integrity necessary for islet revascularization

scientific article published on 7 February 2012

Measurements of cytoplasmic free Ca2+ concentration in human pancreatic islets and insulinoma cells

scientific article published on 01 October 1991

Measurements of membrane potential, transmembrane 45Ca fluxes, cytoplasmic free Ca2+ concentration and insulin release by transplantable rat insulinoma cells maintained in tissue culture

scientific article

Mechanism of action of calcitonin on secretion in rat submandibular gland

scientific article published on 01 July 1989

Mechanisms involved in the regulation of the insulin secretory process

scientific article published on January 1, 1991

Mechanisms of action of entero-insular hormones and neural input on the insulin secretory process

scientific article published on February 1990

Mechanisms of action of peroral antidiabetics. Sulfonylurea preparations block the ATP-dependent potassium channels

scientific article published on November 26, 1997

Mechanistic understanding of insulin receptor modulation: Implications for the development of anti-diabetic drugs

scientific article published on 17 December 2017

Mint1, a Munc-18-interacting protein, is expressed in insulin-secreting beta-cells

scientific article published on July 2004

Mitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release

scientific article

Mobilization of 45Ca from insulin-producing RINm5F cells attached to microcarriers

scientific article published on 01 December 1984

Mobilization of Ca2+ by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone in permeabilized insulin-secreting RINm5F cells: evidence for separate uptake and release compartments in inositol 1,4,5-trisphosphate-sensitive Ca2+ pool

scientific article published on July 1993

Modifications of Ca2+ signaling by inorganic mercury in PC12 cells

scientific article published on 01 December 1993

Modulation of L-type Ca(2+) channels by distinct domains within SNAP-25.

scientific article

Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic beta-cells

scientific article published on 2 November 2005

Morphological and functional characteristics of the different cell types in the stria vascularis: a comparison between cells obtained from fresh tissue preparations and cells cultured in vitro.

scientific article

Munc18-1 and Munc18-2 proteins modulate beta-cell Ca2+ sensitivity and kinetics of insulin exocytosis differently

scientific article

NMDA receptor dependent anti-diabetic effects.

scientific article

Neither polyphenol-rich red wine nor fenofibrate affects the onset of type-1 diabetes mellitus in the BB rat

article by Karin Åvall et al published September 2018 in Laboratory animal research

Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor

scientific article published on 23 September 2015

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release

scientific article

Neuropeptides in the regulation of islet hormone secretion--localization, effects and mode of action

scientific article published on January 1991

Non-invasive cell type selective in vivo monitoring of insulin resistance dynamics

scientific article published on 22 February 2016

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

scientific article

Noninvasive in vivo imaging of pancreatic islet cell biology

scientific article

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

scientific article published on 10 December 2012

Novel aspects on pancreatic beta-cell signal-transduction

scientific article published on May 2010

On-line monitoring of apoptosis in insulin-secreting cells

scientific article

One-step purification of functional human and rat pancreatic alpha cells.

scientific article published on 20 January 2012

Oscillations in KATP channel activity promote oscillations in cytoplasmic free Ca2+ concentration in the pancreatic beta cell

scientific article published on May 1996

Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance

scientific article published on 01 November 1994

PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation

scientific article published on 16 September 2015

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic beta Cells

scientific article published in Science

Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices

scientific article published on 19 June 2015

Pancreatic islet function in a transgenic mouse expressing fluorescent protein

scientific article published in August 2005

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

scientific article published in March 2018

Parallel changes in nuclear and cytosolic calcium in mouse pancreatic beta-cells.

scientific article published on August 1997

Phase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization

scientific article

Phosphatidylinositol 3-kinase-mediated endocytosis of renal Na+, K+-ATPase alpha subunit in response to dopamine

scientific article

Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells

scientific article

Phosphorylated inositol compounds in beta -cell stimulus-response coupling

scientific article

Phosphorylation of the catalyic alpha-subunit constitutes a triggering signal for Na+,K+-ATPase endocytosis.

scientific article published on April 1998

Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling

scientific article published on December 2006

Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal tubular cells

scientific article published on 01 July 2002

Protein kinase C activity affects glucose-induced oscillations in cytoplasmic free Ca2+ in the pancreatic B-cell

scientific article published on 01 May 1992

Protein kinase C modulates the insulin secretory process by maintaining a proper function of the beta-cell voltage-activated Ca2+ channels.

scientific article

Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity

scientific article published on 14 October 2017

Proteins in the insulin-secreting cell line MIN6 bind the imidazoline compound BL11282.

scientific article published on 15 April 2008

Proteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin resistance

scientific article

Proton microprobe analysis of 15 elements in pancreatic B cells and exocrine pancreas in diabetic Chinese hamsters

scientific article published on 01 January 1987

Proton microprobe analysis of pancreatic beta-cells

scientific article published on 01 January 1985

Pulling force generated by interacting SNAREs facilitates membrane hemifusion.

scientific article

Quantification of glucose cycling and the extent of equilibration of glucose 6-phosphate with fructose 6-phosphate in islets from ob/ob mice

scientific article published on September 1991

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion

scientific journal article

RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin

scientific article published on July 1997

RX871024 induces Ca2+ mobilization from thapsigargin-sensitive stores in mouse pancreatic beta-cells.

scientific article published in February 1998

RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines

scientific article published on 14 July 2006

Rapid association of protein kinase C-epsilon with insulin granules is essential for insulin exocytosis

scientific article published on 25 August 2003

Real-time detection of acetylcholine release from the human endocrine pancreas

scientific article published on 3 May 2012

Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance

scientific article

Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation

scientific article published on January 2008

Receptor-mediated Mn2+ influx in rat hepatocytes: comparison of cells loaded with Fura-2 ester and cells microinjected with Fura-2 salt

scientific article published on August 1994

Receptor-mediated inhibition of renal Na(+)-K(+)-ATPase is associated with endocytosis of its alpha- and beta-subunits

scientific article published on 01 November 1997

Reduction of the cytosolic calcium activity in clonal insulin-releasing cells exposed to glucose

scientific article published on October 1983

Regulation of cytoplasmic free Ca2+ in insulin-secreting cells

scientific article

Regulation of glucagon release from pancreatic A-cells

scientific article published on June 1991

Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na+,K+-ATPase endocytosis

scientific journal article

Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis

scientific article published in October 2004

Reporter islets in the eye reveal the plasticity of the endocrine pancreas

scientific article

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells

scientific article published on November 2007

Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release.

scientific article published on July 1996

Rolf Luft (1914–2007)

SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca2+oscillations in β cell networks

scientific article published on 10 August 2017

SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells

scientific article

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K + -channels in mouse pancreatic β-cells

scientific article published on 01 February 1991

Short and prolonged exposure to hyperglycaemia in human fibroblasts and endothelial cells: metabolic and osmotic effects

scientific article published on 9 May 2014

Short telomeres compromise β-cell signaling and survival

scientific article

Short-term regulation of insulin gene transcription

scientific article

Short-term regulation of insulin gene transcription by glucose

scientific article

Signaling and sites of interaction for RX-871024 and sulfonylurea in the stimulation of insulin release

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Silk matrices promote formation of insulin-secreting islet-like clusters

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Sirt1: a metabolic master switch that modulates lifespan

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Somatostatin promotes accumulation of phospholipids in regenerating liver tissue of rats

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Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets

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Starvation is associated with changes in the elemental composition of the pancreatic beta-cell

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Stimulation of insulin release by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in the clonal cell line RINm5F despite a lowering of the free cytoplasmic Ca2+ concentration

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Stimulation of pancreatic islet beta-cell replication by oncogenes

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Stimulation of the insulin secretory mechanism following barium accumulation in pancreatic beta-cells

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Subcellular distribution of zinc in islet beta-cell fractions

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Sulfhydryl oxidation induces rapid and reversible closure of the ATP-regulated K+ channel in the pancreatic beta-cell

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Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose

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Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism

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Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

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Suppression of insulin release by galanin and somatostatin is mediated by a G-protein. An effect involving repolarization and reduction in cytoplasmic free Ca2+ concentration.

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Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death

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Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects

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Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

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TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in hMSCs

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TNF-α and IFN-γ promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration

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Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

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The Different Faces of the Pancreatic Islet

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The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: a study in a baboon model of diabetes

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The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice

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The eye as a novel imaging site in diabetes research

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The imidazoline compound RX871024 promotes insulinoma cell death independent of AMP-activated protein kinase inhibition

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The imidazoline derivative calmidazolium inhibits voltage-gated Ca(2+)-channels and insulin release but has no effect on the phospholipase C system in insulin producing RINm5F-cells

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The pancreatic beta cell as a paradigm for advances in inositide research

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The pancreatic islet as a signaling hub.

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The pancreatic β-cell in deadly encounter with apolipoprotein CIII.

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The role of inositol and the principles of labelling, extraction, and analysis of inositides in mammalian cells

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The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology

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The stimulatory action of tolbutamide on Ca2+-dependent exocytosis in pancreatic beta cells is mediated by a 65-kDa mdr-like P-glycoprotein

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The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

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Thiol oxidation by 2,2'-dithiodipyridine causes a reversible increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. Role for inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.

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Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion

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Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis

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Transfection of insulin-producing cells with a transforming c-Ha-ras oncogene stimulates phospholipase C activity

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Transplantation into the anterior chamber of the eye for longitudinal, non-invasive in vivo imaging with single-cell resolution in real-time

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Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling

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Two generations of insulinotropic imidazoline compounds

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Two separate plasma membrane Ca2+ carriers participate in receptor-mediated Ca2+ influx in rat hepatocytes

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Tyrosine 537 within the Na+,K+-ATPase alpha-subunit is essential for AP-2 binding and clathrin-dependent endocytosis

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Voltage-activated Na+ currents and their suppression by phorbol ester in clonal insulin-producing RINm5F cells

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X-ray microanalysis of in situ and isolated pancreatic islets

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You are what you eat-Do not blame your mother

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Young capillary vessels rejuvenate aged pancreatic islets

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aP2-Cre-mediated inactivation of estrogen receptor alpha causes hydrometra

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β-Cell Ca(2+) dynamics and function are compromised in aging

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