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List of works by Alan S. Perelson

13 Modelling the in vivo growth rate of HIV: implications for vaccination

article

A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents

scientific article published on 4 April 2018

A direct-acting antiviral drug abrogates viremia in Zika virus-infected rhesus macaques

scientific article published on 01 June 2020

A hepatitis C viral kinetic model that allows for time-varying drug effectiveness.

scientific article published on January 2008

A hepatitis C virus infection model with time-varying drug effectiveness: solution and analysis

scientific article (publication date: August 2014)

A mathematical model of hepatitis C virus dynamics in patients with high baseline viral loads or advanced liver disease

scientific article

A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo

scientific article

A pharmacokinetic/viral kinetic model to evaluate the treatment effectiveness of danoprevir against chronic HCV.

scientific article

A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

scientific article published on 10 January 2017

A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity

scientific article

A stochastic model of cytotoxic T cell responses

article

ANALYSIS OF HEPATITIS C VIRUS INFECTION MODELS WITH HEPATOCYTE HOMEOSTASIS

scientific article published on January 2009

Accelerated immunodeficiency by anti-CCR5 treatment in HIV infection

scientific article

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA.

scientific article

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence

scientific article published on September 2007

Agent-based modeling of host-pathogen systems: The successes and challenges

scientific article published on April 2009

An accurate two-phase approximate solution to an acute viral infection model

scientific article

An age-structured model of hiv infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells.

scientific article published in September 2004

Analysis of hepatitis C viral kinetics during administration of two nucleotide analogues: sofosbuvir (GS-7977) and GS-0938.

scientific article

Analysis of hepatitis C virus decline during treatment with the protease inhibitor danoprevir using a multiscale model

scientific article

Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture

scientific article

Antibody responses during hepatitis B viral infection

scientific article

Antigen-Stimulated CD4 T Cell Expansion Can Be Limited by Their Grazing of Peptide–MHC Complexes ⬇️

scientific article published on April 19, 2013

Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection

scientific article published on 25 April 2022

Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips

scientific article published on 17 October 2008

Backward bifurcations and multiple equilibria in epidemic models with structured immunity

scientific article published on 26 January 2008

CD8+ lymphocyte control of SIV infection during antiretroviral therapy

scientific article published on 11 October 2018

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

scientific article

Characterizing T cell movement within lymph nodes in the absence of antigen

scientific article published on 01 May 2007

Combination Antiviral Therapy for Influenza: Predictions From Modeling of Human Infections ⬇️

scientific article published on March 23, 2012

Competitive exclusion by autologous antibodies can prevent broad HIV-1 antibodies from arising

scientific article

Complete genetic linkage can subvert natural selection

scholarly article

Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay

scientific article published in January 2004

Continuous and discrete modeling of HIV-1 decline on therapy

scientific article published on 02 June 2020

Contribution of follicular dendritic cells to persistent HIV viremia

scientific article published on 08 May 2013

Correlation Between Anti-gp41 Antibodies and Virus Infectivity Decay During Primary HIV-1 Infection.

scientific article published on 20 June 2018

Corrigendum to “Modeling sequence evolution in acute HIV-1 infection” [J. Theor. Biol. 261 (2009) 341–360]

article

Corrigendum: Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article published on February 2017

Current estimates for HIV-1 production imply rapid viral clearance in lymphoid tissues

scientific article

Cyclosporin A

Designing a genome-based HIV incidence assay with high sensitivity and specificity ⬇️

scientific article published on October 23, 2011

Determinants of the efficacy of HIV latency-reversing agents and implications for drug and treatment design

article

Determination of virus burst size in vivo using a single-cycle SIV in rhesus macaques

scholarly article

Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals

scientific article published on May 2003

Determining the relative efficacy of highly active antiretroviral therapy

scientific article published on 6 March 2003

Determining thymic output quantitatively: using models to interpret experimental T-cell receptor excision circle (TREC) data

scientific article

Different Dynamics of CD4+ and CD8+ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus Infection ⬇️

scientific article published on October 15, 2003

Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination

scientific article published on 9 August 2002

Dominance of the CD4(+) T helper cell response during acute resolving hepatitis A virus infection.

scientific article

Drug Effectiveness Explained: The Mathematics of Antiviral Agents for HIV ⬇️

scientific article published on July 13, 2011

Drug resistance and influenza pandemics

scientific article published on 01 May 2002

Duration of an intermittent episode of viremia

scientific article published in July 2005

Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection

scientific article

Dynamic characteristics of HIV-1 reservoirs

scientific article published on March 2006

Dynamic correlation between intrahost HIV-1 quasispecies evolution and disease progression

scientific article

Dynamics of CD4(+) T cell responses against Listeria monocytogenes

scientific article

Dynamics of HIV Infection. Interview by Vicki Glaser

scientific article published in July 2003

Dynamics of T cells and TCR excision circles differ after treatment of acute and chronic HIV infection.

scientific article published in October 2002

Dynamics of T- and B-lymphocyte turnover in a natural host of simian immunodeficiency virus

scientific article

Dynamics of alanine aminotransferase during hepatitis C virus treatment

scientific article published in August 2003

Dynamics of hepatitis B virus infection

scientific article

Dynamics of intermittent viremia during highly active antiretroviral therapy in patients who initiate therapy during chronic versus acute and early human immunodeficiency virus type 1 infection

scientific article published on October 2004

Early HIV RNA decay during raltegravir-containing regimens exhibits two distinct subphases (1a and 1b).

scientific article

Early HIV infection predictions: role of viral replication errors.

scientific article published on 3 July 2018

Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy

scientific article published in July 2002

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

scientific article

Early ribavirin pharmacokinetics, HCV RNA and alanine aminotransferase kinetics in HIV/HCV co-infected patients during treatment with pegylated interferon and ribavirin

scientific article

Editorial: Transplant Rejection and Tolerance-Advancing the Field through Integration of Computational and Experimental Investigation

scientific article published on 30 May 2017

Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics

scientific article

Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C.

scientific article published on 08 February 2013

Effect of target cell availability on HIV-1 production in vitro

scientific article published on 01 February 2002

Effects of aging on influenza virus infection dynamics.

scientific article published on 29 January 2014

Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination

scientific article published on May 2004

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

scientific article

Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing

scientific article

Emergence of HIV-1 drug resistance during antiretroviral treatment

scientific article published on 21 April 2007

Estimates of intracellular delay and average drug efficacy from viral load data of HIV-infected individuals under antiretroviral therapy.

scientific article

Estimating average cellular turnover from 5–bromo–2'–deoxyuridine (BrdU) measurements ⬇️

scientific article published on April 22, 2003

Estimating biologically relevant parameters under uncertainty for experimental within-host murine West Nile virus infection.

scientific article published on 13 April 2016

Estimating drug efficacy and viral dynamic parameters: HIV and HCV

scientific article

Estimating lymphocyte division and death rates from CFSE data

scientific article

Estimating time since infection in early homogeneous HIV-1 samples using a poisson model

scientific article

Estimation of the initial viral growth rate and basic reproductive number during acute HIV-1 infection

scientific article

Evaluation of Multitype Mathematical Models for CFSE-Labeling Experiment Data ⬇️

scientific article published on June 17, 2011

Evolution of drug-resistant viral populations during interruption of antiretroviral therapy

scientific article

Evolution of hepatitis C viral quasispecies after liver transplantation

scientific article published in November 2002

Exploring the Mechanisms of Primary Antibody Responses to T Cell-Dependent Antigens

article

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

scientific article published on 20 July 2020

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection

scientific article

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

scientific article published on June 2009

HIV dynamics with multiple infections of target cells

scientific article

HIV-1 infection and low steady state viral loads

scientific article published in January 2002

HIV-1 viral dynamics studies in the setting of clinical trials--A window of opportunity

scientific article published on 06 March 2007

Hepatitis B virus clearance rate estimates

scientific article published in May 2009

Hepatitis B virus kinetics and mathematical modeling

scientific article published on January 2004

Hepatitis B virus kinetics under antiviral therapy sheds light on differences in hepatitis B e antigen positive and negative infections

scientific article

Hepatitis B virus viral dynamics: effects of drug dose and baseline alanine aminotransferase

scientific article

Hepatitis C Viral Kinetics in Special Populations

scientific article published on January 2008

Hepatitis C Viral Kinetics in the Era of Direct Acting Antiviral Agents and IL28B.

scientific article published on July 2011

Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)

scientific article published on 15 February 2012

Hepatitis C viral kinetics: the past, present, and future

scientific article published on February 2013

Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) dynamics during HCV treatment in HCV/HIV coinfection

scientific article published on 13 November 2003

Hepatitis C virus RNA kinetics: drug efficacy and the rate of HCV-infected cells loss

scientific article published on June 2007

Hepatitis C virus genotype 1a NS5A pretreatment sequence variation and viral kinetics in African American and white patients

scientific article published on 12 August 2005

Hepatitis C virus kinetics in chimeric mice during antiviral therapy

scientific article published in December 2007

High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.

scientific article

High-potency human immunodeficiency virus vaccination leads to delayed and reduced CD8+ T-cell expansion but improved virus control

scientific article

Higher level of replication efficiency of 2009 (H1N1) pandemic influenza virus than those of seasonal and avian strains: kinetics from epithelial cell culture and computational modeling

scientific article

How antigen quantity and quality determine T-cell decisions in lymphoid tissue

scientific article published on 21 April 2008

How germinal centers evolve broadly neutralizing antibodies: the breadth of the follicular helper T cell response.

scientific article published on 6 September 2017

Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches

scientific article

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

scientific article (publication date: 27 May 2008)

Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection

scientific article

Impact of different oseltamivir regimens on treating influenza A virus infection and resistance emergence: insights from a modelling study

scientific article (publication date: April 2014)

Impact of early viral kinetics on T-cell reactivity during antiviral therapy in chronic hepatitis B.

scientific article published in January 2007

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

scientific article

Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus

scientific article published in January 2005

In a subset of subjects on highly active antiretroviral therapy, human immunodeficiency virus type 1 RNA in plasma decays from 50 to <5 copies per milliliter, with a half-life of 6 months

scientific article

In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?

scientific article

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

scientific article published on 29 February 2024

Inferring HIV Escape Rates from Multi-Locus Genotype Data

scientific article

Inferring viral dynamics in chronically HCV infected patients from the spatial distribution of infected hepatocytes

scientific article

Influence of peak viral load on the extent of CD4+ T-cell depletion in simian HIV infection

scientific article published on March 2006

Influenza A virus infection kinetics: quantitative data and models

scientific article

Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia

scientific article

Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection

scientific article

Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication

scientific article published on January 2004

Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models

scientific article

Intracellular hepatitis C modeling predicts infection dynamics and viral protein mechanisms.

scientific article published on 21 March 2018

Introduction to modeling viral infections and immunity

scientific article published on 01 September 2018

Kinetics of coinfection with influenza A virus and Streptococcus pneumoniae

scientific article

Kinetics of hepatitis C virus reinfection after liver transplantation

scientific article published in February 2006

Kinetics of influenza A virus infection in humans

scientific article

Kinetics of virus-specific CD8+ T cells and the control of human immunodeficiency virus infection

scientific article published on September 2004

Liver transplantation with hepatitis C virus-infected graft: interaction between donor and recipient viral strains

scientific article published in July 2003

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.

scientific article published on 04 May 2009

Mathematical Modeling of Subgenomic Hepatitis C Virus Replication in Huh-7 Cells

scientific article

Mathematical analysis of delay differential equation models of HIV-1 infection

scientific article published in July 2002

Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents ⬇️

scientific article published on May 16, 2013

Mathematical modeling of HCV infection and treatment

scientific article published on January 2009

Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses.

scientific article published on January 2013

Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release

scientific article published on 05 November 2020

Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production

scientific article published in April 2005

Mathematical modeling of viral kinetics: a tool to understand and optimize therapy

scientific article

Mathematical modeling of within-host Zika virus dynamics

article

Mathematical modelling of HCV infection: what can it teach us in the era of direct-acting antiviral agents?

scientific article published on 5 October 2012

Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy

scientific article published on 09 June 2021

Modeling HCV kinetics under therapy using PK and PD information

article

Modeling HIV persistence, the latent reservoir, and viral blips

scientific article published on 17 June 2009

Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon

scientific article (publication date: July 2009)

Modeling T cell proliferation and death in vitro based on labeling data: generalizations of the Smith-Martin cell cycle model

scientific article

Modeling Viral Spread

scientific article published on 31 August 2016

Modeling Within-Host Dynamics of SARS-CoV-2 Infection: A Case Study in Ferrets

scientific article published on 18 August 2021

Modeling amantadine treatment of influenza A virus in vitro.

scientific article published on 23 July 2008

Modeling and Simulation of Aggregation of Membrane Protein LAT with Molecular Variability in the Number of Binding Sites for Cytosolic Grb2-SOS1-Grb2 ⬇️

scientific article published on January 1, 2012

Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments

scientific article

Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assay

scientific article

Modeling complex decay profiles of hepatitis B virus during antiviral therapy

scientific article published on January 2009

Modeling deuterated glucose labeling of T-lymphocytes

scientific article

Modeling hepatitis C virus dynamics: Liver regeneration and critical drug efficacy

scientific article

Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy

scientific article

Modeling long-term HIV dynamics and antiretroviral response: effects of drug potency, pharmacokinetics, adherence, and drug resistance

scientific article published in July 2005

Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors

scientific article

Modeling quasispecies and drug resistance in hepatitis C patients treated with a protease inhibitor

scientific article

Modeling sequence evolution in HIV-1 infection with recombination

scientific article published on 6 April 2013

Modeling sequence evolution in acute HIV-1 infection

scientific article published on 04 August 2009

Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life

scientific article

Modeling the Effects of Morphine on Simian Immunodeficiency Virus Dynamics

scientific article

Modeling the Effects of Morphine-Altered Virus Specific Antibody Responses on HIV/SIV Dynamics

article

Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells

scientific article published on 23 October 2015

Modeling the acute and chronic phases of Theiler murine encephalomyelitis virus infection

scientific article published on 30 January 2013

Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection

scientific article

Modeling the effects of vaccination on chronically infected HIV-positive patients

scientific article published in December 2002

Modeling the long-term control of viremia in HIV-1 infected patients treated with antiretroviral therapy

scientific article published in March 2004

Modeling the mechanisms of acute hepatitis B virus infection

scientific article

Modeling the within-host dynamics of HIV infection

scientific article

Modeling viral and drug kinetics: hepatitis C virus treatment with pegylated interferon alfa-2b

scientific article published in January 2003

Modeling viral kinetics and treatment outcome during alisporivir interferon-free treatment in hepatitis C virus genotype 2 and 3 patients

scientific article published on April 2014

Modeling within-host HIV-1 dynamics and the evolution of drug resistance: trade-offs between viral enzyme function and drug susceptibility

scientific article

Modeling within-host dynamics of influenza virus infection including immune responses

scientific article

Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

scientific article

Modelling hepatitis C therapy--predicting effects of treatment

scientific article

Modelling hepatitis C virus kinetics: the relationship between the infected cell loss rate and the final slope of viral decay.

scientific article

Modelling how ribavirin improves interferon response rates in hepatitis C virus infection

scientific article published on December 2004

Modelling the effects of phylogeny and body size on within-host pathogen replication and immune response

scientific article published in November 2017

Modelling the impact of antigen kinetics on T-cell activation and response

article

Modelling the interaction between danoprevir and mericitabine in the treatment of chronic HCV infection.

scientific article published on 10 November 2015

Modelling viral and immune system dynamics

scientific article

Models of SIV rebound after treatment interruption that involve multiple reactivation events

scientific article published on 01 October 2020

Modulation of HCV replication after combination antiretroviral therapy in HCV/HIV co-infected patients.

scientific article

Molecular clock of HIV-1 envelope genes under early immune selection

scientific article

Multiplicity of human immunodeficiency virus infections in lymphoid tissue

scientific article published on August 2004

Mutagenic effects of ribavirin in vivo

scientific article published in October 2005

NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains.

scientific article

Naïve and memory cell turnover as drivers of CCR5-to-CXCR4 tropism switch in human immunodeficiency virus type 1: implications for therapy

scientific article

New kinetic models for the hepatitis C virus

scientific article

Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean

scientific article published on 18 October 2017

ON IDENTIFIABILITY OF NONLINEAR ODE MODELS AND APPLICATIONS IN VIRAL DYNAMICS.

scientific article

On the Death Rate of Abortively Infected Cells: Estimation from Simian-Human Immunodeficiency Virus Infection

scientific article

Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART.

scientific article published in November 2005

Optimal viral production

scientific article published on 01 November 2003

Parameter identifiability and estimation of HIV/AIDS dynamic models

scientific article published on 5 February 2008

Persistence and emergence of X4 virus in HIV infection

scientific article

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

article

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

scientific article published on 27 January 2014

Pharmacodynamics of PEG-IFN alpha differentiate HIV/HCV coinfected sustained virological responders from nonresponders

scientific article published in May 2006

Pharmacodynamics of antiretroviral agents in HIV-1 infected patients: using viral dynamic models that incorporate drug susceptibility and adherence

scientific article published in April 2006

Polyspecificity of T cell and B cell receptor recognition

scientific article

Post-treatment control of HIV infection

scientific article published on 13 April 2015

Precise determination of time to reach viral load set point after acute HIV-1 infection.

scientific article published on December 2012

Predicting the impact of a nonsterilizing vaccine against human immunodeficiency virus

scientific article published on October 2004

Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation

scientific article

Prevalence of end of treatment RNA-positive/sustained viral response in HCV patients treated with sofosbuvir combination therapies

scientific article published on 17 October 2016

Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo

scientific article published on 16 March 2015

Quantification of Ebola virus replication kinetics in vitro

scientific article published on 02 November 2020

Quantification of Hepatitis C Virus Cell-to-Cell Spread Using a Stochastic Modeling Approach

scientific article published on April 2015

Quantifying T lymphocyte turnover ⬇️

scientific article published on January 9, 2013

Quantifying antiviral activity optimizes drug combinations against hepatitis C virus infection

scientific article published on 7 February 2017

Quantifying the contribution of Fc-mediated effector functions to the antiviral activity of anti-HIV-1 IgG1 antibodies in vivo

scientific article published on 14 July 2020

Quantifying the diversification of hepatitis C virus (HCV) during primary infection: estimates of the in vivo mutation rate

scientific article

Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus

scientific article

Quantifying the turnover of transcriptional subclasses of HIV-1-infected cells

scientific article

Rapid emergence of protease inhibitor resistance in hepatitis C virus

scientific article

Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population.

scientific article published on 22 December 2015

Recombination increases human immunodeficiency virus fitness, but not necessarily diversity

scientific article published in June 2008

Regulation of T cell expansion by antigen presentation dynamics

scientific article

Reply to Padmanabhan and Dixit: Hepatitis C virus entry inhibitors for optimally boosting direct-acting antiviral-based treatments

scientific article published on 16 May 2017

Reply to: Danoprevir pharmacokinetic/viral kinetic model for treating chronic HCV - some considerations

scientific article published in April 2016

Residual Viremia in Treated HIV+ Individuals

scientific article

Retention of antigen on follicular dendritic cells and B lymphocytes through complement-mediated multivalent ligand-receptor interactions: theory and application to HIV treatment

scientific article published in April 2002

Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus

scientific article

Ribavirin: is it a mutagen for hepatitis C virus?

scientific article published in May 2007

SPMM: estimating infection duration of multivariant HIV-1 infections

scientific article published on 31 December 2015

Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial

scientific article published on 07 October 2021

Scaling aspects of lymphocyte trafficking

scientific article (publication date: 7 March 2009)

Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration.

scientific article

Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis

scientific article

Silibinin mode(s) of action against hepatitis C virus: A controversy yet to be resolved ⬇️

scientific article published on June 27, 2011

Simian immunodeficiency virus SIVagm dynamics in African green monkeys

scientific article

Simulation and prediction of the adaptive immune response to influenza A virus infection

scientific article published on 13 May 2009

Single Cell Laser Capture Microdissection Reveals the Hepatitis C Viral Landscape in the Human Liver

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification

scientific article

Some scaling principles for the immune system

scientific article published on 01 April 2004

Spontaneous Clearance of Viral Infections by Mesoscopic Fluctuations ⬇️

scientific article published on June 5, 2012

Stochastic Theory of Early Viral Infection: Continuous versus Burst Production of Virions ⬇️

scientific article published on February 3, 2011

Stochastic model of an influenza epidemic with drug resistance

scientific article published on 17 May 2007

Stochastic models of lymphocyte proliferation and death

scientific article

Stochastic stage-structured modeling of the adaptive immune system.

scientific article published in January 2003

Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence

article published in the Proceedings of the National Academy of Sciences of the United States of America

The Analysis of HIV Dynamics Using Mathematical Models

article

The Role of Infected Cell Proliferation in the Clearance of Acute HBV Infection in Humans

scientific article published on 18 November 2017

The challenges of modelling antibody repertoire dynamics in HIV infection

scientific article published in September 2015

The complexity of complexes in signal transduction.

scientific article

The distribution of viral blips observed in HIV-1 infected patients treated with combination antiretroviral therapy

scientific article

The effect of early versus delayed challenge after vaccination in controlling SHIV 89.6P infection

scientific article published on 14 September 2008

The effects of thymic selection on the range of T cell cross-reactivity

scientific article published on December 2005

The extrahepatic contribution to HCV plasma viremia

scientific article published on 25 July 2006

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

scientific article published on June 2009

The hepatitis C virus NS5A inhibitor daclatasvir has a dual mode of action and leads to a new virus half-life estimate ⬇️

scientific article published on July 1, 2013

The life span of ganglionic glia in murine sensory ganglia estimated by uptake of bromodeoxyuridine.

scientific article published in March 2004

The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?

scientific article published on 31 August 2017

The probability of HIV infection in a new host and its reduction with microbicides

scientific article published on 28 March 2008

The role of cells refractory to productive infection in acute hepatitis B viral dynamics

scholarly article

Towards multiscale modeling of influenza infection ⬇️

scientific article published on April 19, 2013

Transient viremia, plasma viral load, and reservoir replenishment in HIV-infected patients on antiretroviral therapy

scientific article published on August 2007

Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences

scientific article published on 02 December 2016

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

scientific article

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

scientific article

Treatment of hepatitis C virus infection with interferon and small molecule direct antivirals: viral kinetics and modeling

scientific article

Treatment of hepatitis C with an interferon-based lead-in phase: a perspective from mathematical modelling

scientific article

Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline

scientific article published on May 2008

Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration.

scientific article published on 5 July 2017

Treatment-mediated alterations in HIV fitness preserve CD4+ T cell counts but have minimal effects on viral load

scientific article

Triphasic decline of hepatitis C virus RNA during antiviral therapy

scientific article published in July 2007

Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus

scientific article

Turnover rates of B cells, T cells, and NK cells in simian immunodeficiency virus-infected and uninfected rhesus macaques

scientific article published in March 2003

Understanding silibinin’s modes of action against HCV using viral kinetic modeling ⬇️

scientific article published on January 13, 2012

Understanding the mechanisms and limitations of immune control of HIV.

scientific article published on April 2007

Understanding the nature of early HCV RNA blips and the use of mathematical modeling of viral kinetics during IFN-based therapy

scientific article published on 30 June 2011

Understanding triphasic HCV decline during treatment in the era of IL28B polymorphisms and direct acting antiviral agents via mathematical modeling ⬇️

scientific article published on December 13, 2012

Use of laser capture microdissection to map hepatitis C virus-positive hepatocytes in human liver

scientific article

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape

scientific article

Viral Blip Dynamics during Highly Active Antiretroviral Therapy ⬇️

scientific article published on November 1, 2003

Viral and latent reservoir persistence in HIV-1-infected patients on therapy

scientific article

Viral decay dynamics in HIV-infected patients receiving ritonavir-boosted saquinavir and efavirenz with or without enfuvirtide: a randomized, controlled trial (HIV-NAT 012).

scientific article published on 25 September 2006

Viral dynamics and response differences in HCV-infected African American and white patients treated with IFN and ribavirin

scientific article published in June 2003

Viral dynamics during primary simian immunodeficiency virus infection: effect of time-dependent virus infectivity

scientific article

Viral dynamics of hepatitis B virus DNA in human immunodeficiency virus-1-hepatitis B virus coinfected individuals: similar effectiveness of lamivudine, tenofovir, or combination therapy

scientific article published on April 2009

Viral kinetic modeling: state of the art

scientific article

Virus dynamics and immune responses during treatment in patients coinfected with hepatitis C and HIV.

scientific article published on February 2004

Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses?

scientific article (publication date: July 2008)

Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys

scientific article (publication date: April 2017)

Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies

scientific article published on August 2017

Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article (publication date: December 2016)

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