List of works - Philippe Jay

"The immortal DNA strand": difficult to digest?

scientific article published on 01 April 2010

A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts

scientific journal article

ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells.

scientific article

An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity

scientific article

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium

scientific article published on 15 September 2008

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

scientific article

DCAMKL-1 expression identifies Tuft cells rather than stem cells in the adult mouse intestinal epithelium

scientific article published on 29 October 2009

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. ⬇️

scientific article

Diversification pattern of the HMG and SOX family members during evolution.

scientific article

Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells.

scientific article

Further complexity of the human SOX gene family revealed by the combined use of highly degenerate primers and nested PCR

scientific journal article

Hierarchy and plasticity in the crypt: back to the drawing board.

scientific article

Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation ⬇️

scientific article published on March 29, 2011

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

scientific article

Intestinal stem cells: thirty years of a long and exemplary story

scientific article

Intestinal tuft cells: epithelial sentinels linking luminal cues to the immune system.

scientific article

Isolation and regional mapping of cDNAs expressed during early human development.

scientific article published on January 1997

Loss of APC Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in LGR5+ Intestinal Stem Cells

scientific article published on 25 March 2020

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

scientific journal article

Phosphorylation of an N-terminal motif enhances DNA-binding activity of the human SRY protein.

scientific article published on April 1998

Random chromosome segregation in mouse intestinal epithelial stem cells.

scientific article published on May 2013

SOX22 is a new member of the SOX gene family, mainly expressed in human nervous tissue

scientific article

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

scientific article

Single cell next generation sequencing and characterization of new cell types

scientific article published on 25 May 2016

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

scientific article published in Nature

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

scientific journal article

The cell proliferation antigen Ki-67 organises heterochromatin

scientific journal article

The cytosolic bacterial peptidoglycan sensor Nod2 affords stem cell protection and links microbes to gut epithelial regeneration

scientific article published on 29 May 2014

The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

scientific article

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

scientific article

The intestinal epithelium tuft cells: specification and function

scientific article

Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa

scientific article published on May 3, 2012

List of works by Philippe Jay

"The immortal DNA strand": difficult to digest?

A 20-amino acid module of protein kinase C{epsilon} involved in translocation and selective targeting at cell-cell contacts

ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells.

An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

DCAMKL-1 expression identifies Tuft cells rather than stem cells in the adult mouse intestinal epithelium

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. ⬇️

Diversification pattern of the HMG and SOX family members during evolution.

Expression of the carcinoembryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells.

Further complexity of the human SOX gene family revealed by the combined use of highly degenerate primers and nested PCR

Hierarchy and plasticity in the crypt: back to the drawing board.

Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation ⬇️

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

Intestinal stem cells: thirty years of a long and exemplary story

Intestinal tuft cells: epithelial sentinels linking luminal cues to the immune system.

Isolation and regional mapping of cDNAs expressed during early human development.

Loss of APC Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in LGR5+ Intestinal Stem Cells

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

Phosphorylation of an N-terminal motif enhances DNA-binding activity of the human SRY protein.

Random chromosome segregation in mouse intestinal epithelial stem cells.

SOX22 is a new member of the SOX gene family, mainly expressed in human nervous tissue

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

Single cell next generation sequencing and characterization of new cell types

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

The cell proliferation antigen Ki-67 organises heterochromatin

The cytosolic bacterial peptidoglycan sensor Nod2 affords stem cell protection and links microbes to gut epithelial regeneration

The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

The intestinal epithelium tuft cells: specification and function

Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa