List of works - Luca Pignataro

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

scientific article published in 2022

A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

scientific article published on 26 September 2019

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts

scientific article published on 03 June 2016

Combination of a binaphthol-derived phosphite and a C1-symmetric phosphinamine generates heteroleptic catalysts in Rh- and Pd-mediated reactions

scientific article published on 21 May 2009

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

scientific article

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

scientific article published on 19 February 2013

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

scientific article published on 01 September 2017

Fast Cyclization of a Proline-Derived Self-Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

scientific article published on 22 January 2020

Frontispiece: Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

Innovative Linker Strategies for Tumor-Targeted Drug Conjugates

scientific article published on 20 September 2019

Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

scientific article published on 19 February 2020

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

scientific article

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

scientific article published on 21 September 2017

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

scientific article published on 17 August 2017

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

scientific article published on 27 December 2018

PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions

scientific article published on 01 September 2010

Readily available pyridine- and quinoline-N-oxides as new organocatalysts for the enantioselective allylation of aromatic aldehydes with allyl(trichloro)silane

scientific article published in August 2005

Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions

scientific article published on 18 July 2016

Structurally simple pyridine N-oxides as efficient organocatalysts for the enantioselective allylation of aromatic aldehydes.

scientific article published in February 2006

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

scientific article published on 7 September 2013

Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.

scientific article

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

scientific article published on 22 March 2019

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

scientific article

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

scientific article

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

scientific article published on 16 April 2014

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

scientific article

Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.

scientific article

Tumor Targeting with an isoDGR-Drug Conjugate

scientific article published on 27 April 2017

Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

scientific article published on 01 April 2009

β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate

scientific article published on 01 May 2019

List of works by Luca Pignataro

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts

Combination of a binaphthol-derived phosphite and a C1-symmetric phosphinamine generates heteroleptic catalysts in Rh- and Pd-mediated reactions

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

Fast Cyclization of a Proline-Derived Self-Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

Frontispiece: Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

Innovative Linker Strategies for Tumor-Targeted Drug Conjugates

Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions

Readily available pyridine- and quinoline-N-oxides as new organocatalysts for the enantioselective allylation of aromatic aldehydes with allyl(trichloro)silane

Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions

Structurally simple pyridine N-oxides as efficient organocatalysts for the enantioselective allylation of aromatic aldehydes.

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.

Tumor Targeting with an isoDGR-Drug Conjugate

Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate