List of works - Justin Ashworth

An explorable public transcriptomics compendium for eukaryotic microalgae

Assessment of the optimization of affinity and specificity at protein-DNA interfaces

scientific article published on 23 April 2009

Computational redesign of endonuclease DNA binding and cleavage specificity

scientific article

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

scientific article

Evolution of context dependent regulation by expansion of feast/famine regulatory proteins

scientific article

Exploitation of binding energy for catalysis and design

scientific article published on October 2009

Genome-wide diel growth state transitions in the diatom Thalassiosira pseudonana.

scientific article published on 17 April 2013

Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals

scientific article published on 7 January 2016

Inference of expanded Lrp-like feast/famine transcription factor targets in a non-model organism using protein structure-based prediction

scientific article

Mutations in NOTCH1 cause Adams-Oliver syndrome

scientific article (publication date: 4 September 2014)

Pan-transcriptomic analysis identifies coordinated and orthologous functional modules in the diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum

scientific article published on 9 November 2015

Rare variants in neuronal excitability genes influence risk for bipolar disorder

scientific article

Reprogramming homing endonuclease specificity through computational design and directed evolution

scientific article

Reverse engineering systems models of regulation: discovery, prediction and mechanisms ⬇️

scientific article published on December 28, 2011

RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite

scientific article (publication date: 2011)

Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.

scientific article published on March 2007

Structure-based predictions broadly link transcription factor mutations to gene expression changes in cancers

scientific article

Thermodynamics of DNA target site recognition by homing endonucleases.

scientific article published on 18 October 2007

List of works by Justin Ashworth

An explorable public transcriptomics compendium for eukaryotic microalgae

Assessment of the optimization of affinity and specificity at protein-DNA interfaces

Computational redesign of endonuclease DNA binding and cleavage specificity

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

Evolution of context dependent regulation by expansion of feast/famine regulatory proteins

Exploitation of binding energy for catalysis and design

Genome-wide diel growth state transitions in the diatom Thalassiosira pseudonana.

Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals

Inference of expanded Lrp-like feast/famine transcription factor targets in a non-model organism using protein structure-based prediction

Mutations in NOTCH1 cause Adams-Oliver syndrome

Pan-transcriptomic analysis identifies coordinated and orthologous functional modules in the diatoms Thalassiosira pseudonana and Phaeodactylum tricornutum

Rare variants in neuronal excitability genes influence risk for bipolar disorder

Reprogramming homing endonuclease specificity through computational design and directed evolution

Reverse engineering systems models of regulation: discovery, prediction and mechanisms ⬇️

RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite

Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.

Structure-based predictions broadly link transcription factor mutations to gene expression changes in cancers

Thermodynamics of DNA target site recognition by homing endonucleases.