List of works - Jonathan J. Lyons

Atopic dermatitis in children: clinical features, pathophysiology, and treatment

scientific article

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

scientific article

Clinical relevance of inherited genetic differences in human tryptases

scientific article published in 2021

Clinical response to omalizumab in patients with hereditary α-tryptasemia

scientific article published on 09 October 2019

Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis

scientific article published in 2022

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis

scientific article

Distinct Cutaneous Manifestations and Cold-Induced Leukocyte Activation Associated With PLCG2 Mutations.

scientific article published on 11 March 2015

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

scientific article

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

scientific article

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

scientific article published on 17 October 2016

FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy

scientific article

First Identification of an Inherited TPSAB1 Quintuplication in a Patient with Clonal Mast Cell Disease

scientific article published on 11 May 2018

Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8-deficient patients.

scientific article published on 28 January 2016

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease

scientific article

Germline hypomorphic CARD11 mutations in severe atopic disease

scientific article published on 19 June 2017

Glycans Instructing Immunity: The Emerging Role of Altered Glycosylation in Clinical Immunology

scientific article published on 11 June 2015

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia

scientific article published on 23 July 2019

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

scientific article published on 7 December 2015

Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities

scientific article

PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients

scientific article published on 14 July 2017

Primary atopic disorders.

scientific article published on 16 March 2018

Prospective phenotyping of NGLY1-CDDG, the first congenital disorder of deglycosylation

scientific article published on 7 July 2016

The clinical and mechanistic intersection of primary atopic disorders and inborn errors of growth and metabolism

scientific article published on 01 January 2019

List of works by Jonathan J. Lyons

Atopic dermatitis in children: clinical features, pathophysiology, and treatment

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

Clinical relevance of inherited genetic differences in human tryptases

Clinical response to omalizumab in patients with hereditary α-tryptasemia

Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis

Distinct Cutaneous Manifestations and Cold-Induced Leukocyte Activation Associated With PLCG2 Mutations.

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy

First Identification of an Inherited TPSAB1 Quintuplication in a Patient with Clonal Mast Cell Disease

Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8-deficient patients.

GATA3 haploinsufficiency does not block allergic sensitization or atopic disease

Germline hypomorphic CARD11 mutations in severe atopic disease

Glycans Instructing Immunity: The Emerging Role of Altered Glycosylation in Clinical Immunology

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities

PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients

Primary atopic disorders.

Prospective phenotyping of NGLY1-CDDG, the first congenital disorder of deglycosylation

The clinical and mechanistic intersection of primary atopic disorders and inborn errors of growth and metabolism