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List of works by Sisse R Ostrowski

"Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA): Safety and efficacy of low-dose Iloprost, a prostacyclin analogue, in addition to standard therapy, as compared to standard therapy alone, in post-cardiac-arrest-syndrome patients."

scientific article published on 21 October 2019

2B4 expression on natural killer cells increases in HIV-1 infected patients followed prospectively during highly active antiretroviral therapy

article

A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients

scientific article published on 01 August 2011

A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome

scientific article published on 24 March 2022

A low level of CD4+CD28+ T cells is an independent predictor of high mortality in human immunodeficiency virus type 1-infected patients

scientific article published on 15 May 2003

A pilot study to assess the hemostatic function of pathogen-reduced platelets in patients with thrombocytopenia

scientific article

A randomised double-blind pilot trial comparing a mean arterial pressure target of 65 mm Hg versus 72 mm Hg after out-of-hospital cardiac arrest

scientific article published on 31 January 2020

A review of the clinical utility of INR to monitor and guide administration of prothrombin complex concentrate to orally anticoagulated patients

scientific article

A single center, open, randomized study investigating the clinical safety and the endothelial modulating effects of a prostacyclin analog in combination with eptifibatide in patients having undergone primary percutaneous coronary intervention (PCI) f

Absences of Endothelial Microvesicle Changes in the Presence of the Endotheliopathy of Trauma

scientific article published on 4 April 2018

Acute coagulopathy of trauma: balancing progressive catecholamine induced endothelial activation and damage by fluid phase anticoagulation.

scientific article published on 13 August 2010

Acute myocardial infarction is associated with endothelial glycocalyx and cell damage and a parallel increase in circulating catecholamines.

scientific article

Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study

scientific article published on 24 April 2015

Association between sympathoadrenal activation, fibrinolysis, and endothelial damage in septic patients: a prospective study.

scientific article published on 28 January 2014

Biomarkers in patients with Takotsubo cardiomyopathy compared to patients with acute anterior ST-elevation myocardial infarction

scientific article published on 08 January 2020

Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma.

scientific article published on July 2013

Cerebral FDG-PET scanning abnormalities in optimally treated HIV patients

scientific article

Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy

scientific article published on 17 July 2013

Changes in plasma concentrations of interleukin-6 and interleukin-1 receptor antagonists in response to adrenaline infusion in humans

article

Circulating levels of platelet α-granule cytokines in trauma patients

scientific article

Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)-a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy

scientific article published on 05 September 2019

Coagulopathy in patients with acute pulmonary embolism: a pilot study of whole blood coagulation and markers of endothelial damage

scientific article published on 11 October 2016

Coagulopathy, catecholamines, and biomarkers of endothelial damage in experimental human endotoxemia and in patients with severe sepsis: a prospective study

scientific article published on 31 May 2013

Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy.

scientific article published on 12 January 2017

Consecutive thrombelastography clot strength profiles in patients with severe sepsis and their association with 28-day mortality: A prospective study

scientific article published on 14 November 2012

Current management of massive hemorrhage in trauma.

scientific article published on 09 July 2012

Cytokine Autoantibodies Are Associated with Infection Risk and Self-Perceived Health: Results from the Danish Blood Donor Study

scientific article published on 15 January 2020

Cytokines in aging and exercise.

scientific article published in May 2000

Dabigatran and its reversal with recombinant factor VIIa and prothrombin complex concentrate: a Sonoclot in vitro study

scientific article published on 09 June 2014

Data-driven Development of ROTEM and TEG Algorithms for the Management of Trauma Hemorrhage

scientific article published on 01 December 2019

Detection of tPA-Induced Hyperfibrinolysis in Whole Blood by RapidTEG, KaolinTEG, and Functional FibrinogenTEG in Healthy Individuals

scientific article published on 31 January 2012

Discrepant coagulation profile in HIV infection: elevated D-dimer but impaired platelet aggregation and clot initiation

scientific article published on November 2013

Discrepant fibrinolytic response in plasma and whole blood during experimental endotoxemia in healthy volunteers

scientific article

Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study.

scientific article

Early Identification of the Patient with Endotheliopathy of Trauma by Arrival Serum Albumin

scientific article published on 18 October 2017

Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients

scientific article published in 2022

Effect of acute hypobaric hypoxia on the endothelial glycocalyx and digital reactive hyperemia in humans.

scientific article published on 24 November 2014

Effect of delayed onset prostacyclin on markers of endothelial function and damage after subarachnoid hemorrhage.

scientific article published on 7 April 2017

Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury.

scientific article

Effects of anemia and blood transfusion on clot formation and platelet function in patients with septic shock: a substudy of the randomized TRISS trial

scientific article published on 05 November 2018

Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat.

scientific article

Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

scientific article published in June 2012

Elevated levels of soluble urokinase receptor in serum from mycobacteria infected patients: still looking for a marker of treatment efficacy.

scientific article

Endothelial Damage Signals Refractory Acute Kidney Injury in Critically Ill Patients.

scientific article published on June 2017

Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA): safety and efficacy of low-dose prostacyclin administration and blood pressure target in addition to standard therapy, as compared to standard therapy alone, in post-cardiac arrest s

scientific article published on 02 August 2016

Endothelial activation/injury and associations with severity of post-cardiac arrest syndrome and mortality after out-of-hospital cardiac arrest

scientific article published on 11 August 2016

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

scientific article

Erratum to: Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism.

scientific article published on 13 July 2017

Evidence supporting the use of recombinant activated factor VII in congenital bleeding disorders.

scientific article published on 21 July 2010

Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans.

scientific article published on 5 March 2003

Fatal pandemic (H1N1) 2009 influenza A virus infection in a Pennsylvania domestic cat.

scientific article

Fibrinogen in trauma, an evaluation of thrombelastography and rotational thromboelastometry fibrinogen assays

scientific article published on 20 November 2014

Haemostatic function and biomarkers of endothelial damage before and after RBC transfusion in patients with haematologic disease.

scientific article published on 6 March 2015

Haemostatic function and biomarkers of endothelial damage before and after platelet transfusion in patients with acute myeloid leukaemia

scientific article published on 05 June 2015

Haemostatic resuscitation in trauma: the next generation.

scientific article published on December 2016

Hemostatic resuscitation with plasma and platelets in trauma.

scientific article published on April 2012

High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis

scientific article

High Plasma Levels of Intact and Cleaved Soluble Urokinase Receptor Reflect Immune Activation and Are Independent Predictors of Mortality in HIV-1-Infected Patients

article

High Plasma Levels of Neuropeptide Y Correlate With Good Clinical Outcome But are not Correlated to Cerebral Blood Flow or Vasospasm After Subarachnoid Hemorrhage

scientific article published on 01 January 2016

High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality

scientific article published on 01 February 2012

High syndecan-1 levels in acute myeloid leukemia are associated with bleeding, thrombocytopathy, endothelial cell damage, and leukocytosis

scientific article

How I treat patients with massive hemorrhage

scientific article

Hyaluronic Acid Is a Biomarker for Allograft Dysfunction and Predicts 1-Year Graft Loss After Liver Transplantation

scientific article published on 11 September 2018

Hypercoagulability in patients undergoing coronary artery bypass grafting: prevalence, patient characteristics and postoperative outcome.

scientific article published on 18 October 2011

Hypercoagulability in response to elevated body temperature and central hypovolemia.

scientific article published on 29 June 2013

Identified metabolic signature for assessing red blood cell unit quality is associated with endothelial damage markers and clinical outcomes.

scientific article published on 8 January 2016

Immune activation in chronic HIV infection

scientific article published on 01 March 2010

Immune function as predictor of infectious complications and clinical outcome in patients undergoing solid organ transplantation (the ImmuneMo:SOT study): a prospective non-interventional observational trial

scientific article published on 03 July 2019

Impaired Platelet Aggregation and Rebalanced Hemostasis in Patients with Chronic Hepatitis C Virus Infection

scientific article published on 8 May 2017

Impaired production of cytokines is an independent predictor of mortality in HIV-1-infected patients

scientific article published in March 2003

In vitro cell quality of buffy coat platelets in additive solution treated with pathogen reduction technology

scientific article published on 4 October 2010

In-vitro comparison of free oscillation rheometry (ReoRox) and rotational thromboelastometry (ROTEM) in trauma patients upon hospital admission

scientific article published on 01 December 2012

Increased prevalence of leukocytes and elevated cytokine levels in semen from Schistosoma haematobium-infected individuals.

scientific article

Interleukin-6 Infusion During Human Endotoxaemia Inhibits In Vitro Release of the Urokinase Receptor from Peripheral Blood Mononuclear Cells

scientific article published on 01 February 2005

Level of systemic inflammation and endothelial injury is associated with cardiovascular dysfunction and vasopressor support in post-cardiac arrest patients.

scientific article published on 22 September 2017

Low dose Iloprost effect on platelet aggregation in comatose out-of-hospital cardiac arrest patients: A predefined sub-study of the ENDO-RCA randomized -phase 2- trial

scientific article published on 30 December 2019

Low hemorrhage-related mortality in trauma patients in a Level I trauma center employing transfusion packages and early thromboelastography-directed hemostatic resuscitation with plasma and platelets.

scientific article published on 25 April 2013

Low level of procoagulant platelet microparticles is associated with impaired coagulation and transfusion requirements in trauma patients.

scientific article published in November 2014

Low-level viremia and proviral DNA impede immune reconstitution in HIV-1-infected patients receiving highly active antiretroviral therapy

scientific article published on 30 December 2004

Management of bleeding in major burn surgery

scientific article published on 03 October 2018

Management of major blood loss: an update.

scientific article published on 06 July 2010

Marker of Endothelial Dysfunction Asymmetric Dimethylarginine Is Elevated in HIV Infection but Not Associated With Subclinical Atherosclerosis

scientific article

Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate.

scientific article published on 8 December 2015

Markers of endothelial dysfunction in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs. ringer's acetate.

scientific article

Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection

scientific article

Mild induced hypothermia: effects on sepsis-related coagulopathy--results from a randomized controlled trial

scientific article

Monitoring of dabigatran anticoagulation and its reversal in vitro by thrombelastography

scientific article published on 04 August 2014

Outcome of an enhanced diagnostic pipeline for patients suspected of inherited thrombocytopenia

scientific article published on 25 March 2019

Persistent inflammation and endothelial activation in HIV-1 infected patients after 12 years of antiretroviral therapy

scientific article

Plasma Concentration of Biomarkers Reflecting Endothelial Cell- and Glycocalyx Damage are Increased in Patients with Suspected St-Elevation Myocardial Infarction Complicated by Cardiogenic Shock.

scientific article published on 12 February 2018

Plasma Levels of Intact and Cleaved Urokinase Receptor Decrease in HIV-1-Infected Patients Initiating Highly Active Antiretroviral Therapy

article

Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome

scientific article published on 14 March 2005

Platelet aggregation following trauma: a prospective study

scientific article published in January 2014

Platelet increment is not associated with endothelial damage in haematological patients: a prospective observational study

scientific article published on 05 July 2019

Pre-hospital transfusion of plasma in hemorrhaging trauma patients independently improves hemostatic competence and acidosis

scientific article published on 9 December 2016

Prediction of non-recovery from ventilator-demanding acute respiratory failure, ARDS and death using lung damage biomarkers: data from a 1200-patient critical care randomized trial.

scientific article

Pretransplantation vitamin A plasma levels and risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation

scientific article published on 26 November 2019

Prevalence of cerebral and pulmonary thrombosis in patients with cyanotic congenital heart disease.

scientific article published on 5 June 2015

Profound endothelial damage predicts impending organ failure and death in sepsis

scientific article published on 15 January 2015

Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults.

scientific article published in November 2007

Residual viraemia in HIV-1-infected patients with plasma viral load <or=20 copies/ml is associated with increased blood levels of soluble immune activation markers.

scientific article

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections: The VIPER-OCTA Randomized Clinical Pilot Trial

scientific article published on 01 October 2018

Resuscitation with Pooled and Pathogen-Reduced Plasma Attenuates the Increase in Brain Water Content following Traumatic Brain Injury and Hemorrhagic Shock in Rats.

scientific article published on 14 September 2016

Rethinking platelet function: Thrombocytopenia induced immunodeficiency in critical illness ⬇️

scientific article published on August 12, 2011

Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis.

scientific article published in September 2008

Self-reported fatigue common among optimally treated HIV patients: no correlation with cerebral FDG-PET scanning abnormalities

scientific article published on 22 August 2006

Seroprevalence of SARS-CoV-2 antibodies in social housing areas in Denmark

scientific article published on 10 February 2022

Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

scientific article published on 09 February 2017

Soluble urokinase plasminogen activator receptor during allogeneic stem cell transplantation

scientific article published on 01 April 2011

Soluble urokinase receptor levels in plasma during 5 years of highly active antiretroviral therapy in HIV-1-infected patients

scientific article published in April 2004

Storage time of platelet concentrates and risk of a positive blood culture: a nationwide cohort study

scientific article published on 22 November 2017

Sympathoadrenal activation and endothelial damage are inter correlated and predict increased mortality in patients resuscitated after out-of-hospital cardiac arrest. a post Hoc sub-study of patients from the TTM-trial

scientific article

Sympathoadrenal activation and endothelial damage in patients with varying degrees of acute infectious disease: an observational study.

scientific article published on 8 October 2014

T cell subsets in HIV infected patients after successful combination antiretroviral therapy: impact on survival after 12 years

scientific article

T-cell subset distribution in HIV-1-infected patients after 12 years of treatment-induced viremic suppression

scientific article published in November 2012

The Influence of Low Platelet Count on Whole Blood Aggregometry Assessed by Multiplate

scientific article published on 14 March 2011

The anticoagulant effect of therapeutic levels of dabigatran in atrial fibrillation evaluated by thrombelastography (TEG®), Hemoclot Thrombin Inhibitor (HTI) assay and Ecarin Clotting Time (ECT).

scientific article published on 5 January 2018

The effect of intraoperative and 6-h postoperative intravenous administration of low-dose prostacyclin on the endothelium, hemostasis, and hemodynamics in patients undergoing a pancreaticoduodenoctemy: a randomized-controlled pilot study

scientific article published on 6 December 2016

The effect of pre-operative methylprednisolone on early endothelial damage after total knee arthroplasty: a randomised, double-blind, placebo-controlled trial

scientific article published on 26 July 2017

The effect of targeted temperature management on coagulation parameters and bleeding events after out-of-hospital cardiac arrest of presumed cardiac cause

scientific article published on 8 September 2015

The impact of blood type on transfusion after major emergency abdominal surgery

scientific article published on 10 December 2018

The prognostic value of thrombelastography in identifying neurosurgical patients with worse prognosis.

scientific article published on July 2011

Thrombelastography and biomarker profiles in acute coagulopathy of trauma: a prospective study.

scientific article published on 26 October 2011

Thrombelastography and tromboelastometry in assessing coagulopathy in trauma.

scientific article published on 23 September 2009

Thrombelastography detects dabigatran at therapeutic concentrations in vitro to the same extent as gold-standard tests.

scientific article published on 9 January 2016

Thrombelastography early amplitudes in bleeding and coagulopathic trauma patients: Results from a multicenter study.

scientific article published on 3 November 2017

Thromboelastography in patients with severe sepsis: a prospective cohort study

scientific article published on 21 November 2014

Thromboelastography on plasma reveals delayed clot formation and accelerated clot lyses in HIV-1 infected persons compared with healthy controls

scientific article published on 24 September 2015

Thromboembolic Complications in Fontan Patients: Population-Based Prevalence and Exploration of the Etiology

scientific article published on 28 July 2012

Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

scientific article published on 04 April 2019

Transfusion requirements and clinical outcome in intensive care patients receiving continuous renal replacement therapy: comparison of prostacyclin vs. heparin prefilter administration

scientific article

Transfusion requirements in elective cardiopulmonary bypass surgery patients: predictive value of Multiplate and Thromboelastography (TEG) Platelet Mapping Assay.

scientific article

Transfusion therapy in paediatric trauma patients: a review of the literature

scientific article published on 15 February 2015

Trauma-induced coagulopathy: standard coagulation tests, biomarkers of coagulopathy, and endothelial damage in patients with traumatic brain injury.

scientific article published on 5 February 2013

Viscoelastic guidance of resuscitation.

scientific article published on April 2014

iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial

scientific article published on 18 October 2017

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