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List of works by Henry N. Higgs

A complex containing lysine-acetylated actin inhibits the formin INF2

scientific article published on 08 April 2019

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division.

scientific article

A role for myosin II in mammalian mitochondrial fission

scientific article published on 30 January 2014

Actin Nucleation: Cortactin Caught in the Act

scientific article published on 01 September 2002

Actin cytoskeleton: formins lead the way.

scientific article published in July 2004

Actin dynamics: growth from dendritic branches.

scientific article

Actin filaments as dynamic reservoirs for Drp1 recruitment

scientific article

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

scientific article published on 26 November 2015

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

scientific journal article

Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes

scientific article

Assembly and turnover of short actin filaments by the formin INF2 and profilin

scientific article

Assembly of filopodia by the formin FRL2 (FMNL3)

scientific article

Bi-modal regulation of a formin by srGAP2

scientific article

Branching out: cortactin stabilizes actin networks generated by the Arp2/3 complex

scientific article published on 01 April 2001

Calcium-mediated actin reset (CaAR) mediates acute cell adaptations

scientific article

Cdc42-induced actin filaments are protected from capping protein

article

Cell type-dependent mechanisms for formin-mediated assembly of filopodia.

scientific article

Cloning of a phosphatidic acid-preferring phospholipase A1 from bovine testis.

scientific article

Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse

scientific article

Connecting the cytoskeleton to the endoplasmic reticulum and Golgi.

scientific article

Control of the assembly of ATP- and ADP-actin by formins and profilin.

scientific article published in January 2006

Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex.

scientific article

Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules

scientific article published on 12 October 2011

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

scientific article published on April 2000

Discussing the morphology of actin filaments in lamellipodia.

scientific article

Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins

scientific article

Erratum: Corrigendum: Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

article

FMNL3 FH2–actin structure gives insight into formin-mediated actin nucleation and elongation

scientific article

Focal Adhesions Undergo Longitudinal Splitting into Fixed-Width Units

scientific article published on 14 June 2018

Formin proteins: a domain-based approach.

scientific article

Function-Oriented Studies Targeting Pectenotoxin 2: Synthesis of the GH-Ring System and a Structurally Simplified Macrolactone

scientific article published on 13 September 2017

INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.

scientific article

INF2 is an endoplasmic reticulum-associated formin protein.

scientific article

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

scientific article published on 15 November 2017

Interactions of Acanthamoeba profilin with actin and nucleotides bound to actin.

scientific article published in August 1998

Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.

scientific article published on 25 April 2013

Isoform-selective chemical inhibition of mDia-mediated actin assembly.

scientific article published on October 2009

Listeria motility: biophysics pushes things forward.

scientific article

Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein (WASp) for their morphology.

scientific article published on 6 May 2004

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

scientific article published in Journal of Biological Chemistry

Membrane Lipids Have Multiple Effects on Interfacial Catalysis by a Phosphatidic Acid-Preferring Phospholipase A1 from Bovine Testis†

article

Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury

scientific article published on 24 June 2016

Monitoring ATP hydrolysis and ATPase inhibitor screening using (1)H NMR.

scientific article published on October 2014

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

scientific article

Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing.

scientific article

Nanostructured self-assembly of inverted formin 2 (INF2) and F-actin-INF2 complexes revealed by atomic force microscopy

scientific article

Novel roles for actin in mitochondrial fission

scientific article

Phylogenetic analysis of the formin homology 2 domain

scientific article

Purification and Properties of a Phosphatidic Acid-preferring Phospholipase A from Bovine Testis

scientific article published in Journal of Biological Chemistry

Purification of Recombinant Acyl-Coenzyme A:Cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy ⬇️

scientific article published on October 29, 2010

Receptor-mediated Drp1 oligomerization on endoplasmic reticulum.

scientific article published on 20 November 2017

Regulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itself

scientific article published on 23 December 2019

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

scientific article published in January 2001

Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)

scientific article

Roles for Ena/VASP proteins in FMNL3-mediated filopodial assembly

scientific article published on 29 October 2018

Scavenger receptor-A functions in phagocytosis of E. coli by bone marrow dendritic cells.

scientific article published on 23 February 2007

Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity

scientific article

Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture

scientific article

The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes.

scientific article

The Pollard lab at Salk: moving the leading edge forward

scientific article published on 12 November 2018

The filamentous actin cross-linking/bundling activity of mammalian formins.

scientific article published on 26 September 2008

The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion

scientific article

The formin FMNL3 is a cytoskeletal regulator of angiogenesis

scientific article

The harder the better: effects of substrate rigidity on cell motility

scientific article published on 01 September 2000

The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.

scientific article

The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complex-dependent actin nucleation.

scientific article published on 17 July 2001

There goes the neighbourhood: Eps8 joins the barbed-end crowd

scientific article published on 01 December 2004

Tools for ‘The Sceptical Chymist’: measuring macromolecular interaction kinetics in live cells by TIR–FRAP

scientific article published on 01 November 2000

Tropomyosin regulates elongation by formin at the fast-growing end of the actin filament.

scientific article published on 15 June 2007

Two distinct actin filament populations have effects on mitochondria, with differences in stimuli and assembly factors

scientific article published on 23 September 2019

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