List of works - Matthew C Pickering

A hybrid CFHR3-1 gene causes familial C3 glomerulopathy.

scientific article

A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry

scientific article published on 25 September 2013

Acute presentation and persistent glomerulonephritis following streptococcal infection in a patient with heterozygous complement factor H-related protein 5 deficiency

scientific article

Annexin A2 Enhances Complement Activation by Inhibiting Factor H

scientific article

Are anti-C1q antibodies different from other SLE autoantibodies?

scientific article published on 27 April 2010

Atypical hemolytic uremic syndrome and genetic aberrations in the complement factor H-related 5 gene

scientific article

Atypical hemolytic uremic syndrome: telling the difference between H and Y.

scientific article

Bilateral gluteal abscesses as a unique manifestation of Fusobacterium septicaemia

scientific article published on 01 February 2000

Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury

scientific article

C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.

scientific article published on April 2014

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation

scientific article published on June 2013

C3 glomerulopathy: a new classification

scientific article published on 06 July 2010

C3 glomerulopathy: clinicopathologic features and predictors of outcome

scientific article published on 31 October 2013

C3 glomerulopathy: consensus report

scientific article published on 30 October 2013

C3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis.

scientific article published on 05 May 2014

Complement C1q and C8 deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness

scientific article published on 04 August 2008

Complement Factor H Limits Immune Complex Deposition and Prevents Inflammation and Scarring in Glomeruli of Mice with Chronic Serum Sickness

scientific article published on 01 December 2004

Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis

scientific article

Complement alternative pathway genetic variation and Dengue infection in the Thai population

scientific article

Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration

scientific article

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

scientific article

Complement factor H-deficient mice develop spontaneous hepatic tumors

scientific article published on 05 May 2020

Complement in human diseases: Lessons from complement deficiencies

scientific article published on 28 May 2009

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury

scientific journal article

Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient mice

scientific article published on 03 September 2009

Dense deposit disease and C3 glomerulopathy

scientific article

Dense deposit disease.

scientific article

Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

scientific article

Detection of complement activation using monoclonal antibodies against C3d.

scientific article published on 24 April 2013

Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis

scientific article

Dimerization of complement factor H-related proteins modulates complement activation in vivo

scientific article

Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis

scientific article published on 22 February 2013

Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase

scientific article published on 2 May 2009

Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice

scientific article

False-positive results obtained using the Mantoux test in Behçet's syndrome: Comment on the article by García-Porrúa et al

scientific article published on 01 December 2000

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

scholarly article by Kate Smith-Jackson et al published 4 February 2019 in Journal of Clinical Investigation

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

scientific article

Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation

scientific article published on 05 December 2013

Lateral medullary syndrome with anti-neuronal antibodies (anti-Ta/Ma2) in primary Sjogren's syndrome.

scientific article published on 20 July 2009

Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency

scientific article published on 26 November 2012

Mesangial immune complex glomerulonephritis due to complement factor D deficiency

scientific article published on 04 April 2007

New approaches to the treatment of dense deposit disease

scientific article published on 5 August 2007

Nonfunctional variant 3 factor H binding proteins as meningococcal vaccine candidates

scientific article

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis

scientific article published on 23 April 2009

Painful myositis in the anti-synthetase syndrome with anti-PL12 antibodies

scientific article published on 17 February 2011

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

scientific article

Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice

scholarly article

Proteomic Profiling of Urinary Protein Excretion in the Factor H-Deficient Mouse

article

Recent insights into C3 glomerulopathy

scientific article published on 10 March 2013

Recurrence of complement factor H-related protein 5 nephropathy in a renal transplant

scientific article

Regulating complement in the kidney: insights from CFHR5 nephropathy ⬇️

scientific article published on November 1, 2011

Relationship between complotype and reported severity of systemic allergic reactions to peanut

scientific article published on 09 February 2012

SLE with C1q deficiency treated with fresh frozen plasma: a 10-year experience

scientific article published on 04 December 2009

Shiga toxin-2 results in renal tubular injury but not thrombotic microangiopathy in heterozygous factor H-deficient mice.

scientific article

Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains

scientific article

Systemic lupus erythematosus, complement deficiency, and apoptosis

scientific article

The development of atypical hemolytic uremic syndrome depends on complement C5

scientific article

Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.

scientific article

Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice

scientific article

Ultraviolet-Radiation-Induced Keratinocyte Apoptosis in C1q-Deficient Mice

scientific article published on 01 July 2001

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H

article by Matthew C Pickering et al published August 2002 in Nature Genetics

List of works by Matthew C Pickering

A hybrid CFHR3-1 gene causes familial C3 glomerulopathy.

A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry

Acute presentation and persistent glomerulonephritis following streptococcal infection in a patient with heterozygous complement factor H-related protein 5 deficiency

Annexin A2 Enhances Complement Activation by Inhibiting Factor H

Are anti-C1q antibodies different from other SLE autoantibodies?

Atypical hemolytic uremic syndrome and genetic aberrations in the complement factor H-related 5 gene

Atypical hemolytic uremic syndrome: telling the difference between H and Y.

Bilateral gluteal abscesses as a unique manifestation of Fusobacterium septicaemia

Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury

C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation

C3 glomerulopathy: a new classification

C3 glomerulopathy: clinicopathologic features and predictors of outcome

C3 glomerulopathy: consensus report

C3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis.

Complement C1q and C8 deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness

Complement Factor H Limits Immune Complex Deposition and Prevents Inflammation and Scarring in Glomeruli of Mice with Chronic Serum Sickness

Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis

Complement alternative pathway genetic variation and Dengue infection in the Thai population

Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction

Complement factor H-deficient mice develop spontaneous hepatic tumors

Complement in human diseases: Lessons from complement deficiencies

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury

Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient mice

Dense deposit disease and C3 glomerulopathy

Dense deposit disease.

Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

Detection of complement activation using monoclonal antibodies against C3d.

Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis

Dimerization of complement factor H-related proteins modulates complement activation in vivo

Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis

Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase

Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice

False-positive results obtained using the Mantoux test in Behçet's syndrome: Comment on the article by García-Porrúa et al

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation

Lateral medullary syndrome with anti-neuronal antibodies (anti-Ta/Ma2) in primary Sjogren's syndrome.

Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency

Mesangial immune complex glomerulonephritis due to complement factor D deficiency

New approaches to the treatment of dense deposit disease

Nonfunctional variant 3 factor H binding proteins as meningococcal vaccine candidates

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis

Painful myositis in the anti-synthetase syndrome with anti-PL12 antibodies

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice

Proteomic Profiling of Urinary Protein Excretion in the Factor H-Deficient Mouse

Recent insights into C3 glomerulopathy

Recurrence of complement factor H-related protein 5 nephropathy in a renal transplant

Regulating complement in the kidney: insights from CFHR5 nephropathy ⬇️

Relationship between complotype and reported severity of systemic allergic reactions to peanut

SLE with C1q deficiency treated with fresh frozen plasma: a 10-year experience

Shiga toxin-2 results in renal tubular injury but not thrombotic microangiopathy in heterozygous factor H-deficient mice.

Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains

Systemic lupus erythematosus, complement deficiency, and apoptosis

The development of atypical hemolytic uremic syndrome depends on complement C5

Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.

Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice

Ultraviolet-Radiation-Induced Keratinocyte Apoptosis in C1q-Deficient Mice

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H