List of works - Pierre-Emmanuel Gleizes

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism ⬇️

scientific article

An overview of pre-ribosomal RNA processing in eukaryotes

scientific article

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.

scientific article

Cell release of bioactive fibroblast growth factor 2 by exon 6-encoded sequence of vascular endothelial growth factor

scientific article published on 01 September 1997

Characterization of the lipid envelope of exosome encapsulated HEV particles protected from the immune response.

scientific article published on 5 May 2017

Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.

scientific article published on 21 June 2019

Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models.

scientific article published on 7 December 2017

Diamond Blackfan anemia: ribosomal proteins going rogue.

scientific article published on April 2011

Diamond-Blackfan anemia reveals the dark side of ribosome biogenesis

scientific article published in January 2009

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

scientific journal article

Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia

scientific article

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

scientific article

Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae

scientific article

Germline mutation of RPS20, encoding a ribosomal protein, causes predisposition to hereditary nonpolyposis colorectal carcinoma without DNA mismatch repair deficiency

scientific article

Good Vibrations: Structural Remodeling of Maturing Yeast Pre-40S Ribosomal Particles Followed by Cryo-Electron Microscopy

scientific article published on 03 March 2020

Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

scientific journal article

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

scientific article published on 01 April 2021

Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1.

scientific article published on November 1996

Impaired ribosome biogenesis in Diamond-Blackfan anemia

scientific article

Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models

scientific article published on 06 June 2019

Labeling of basic fibroblast growth factor with digoxigenin: a nonradioactive probe for biochemical and cytological applications.

scientific article published on June 1994

Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae

scientific article

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation

scientific article published on 01 February 2019

Maturation of pre-40S particles in yeast and humans

scientific article published on 08 November 2018

Molecular approaches to diagnose Diamond-Blackfan anemia: The EuroDBA experience.

scientific article published on 25 October 2017

Molecular basis of Diamond Blackfan anemia: structure and function analysis of RPS19

scientific article

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder

scientific article

NHP2 deficiency impairs rRNA biogenesis and causes pulmonary fibrosis and Høyeraal-Hreidarsson syndrome

scientific article published on 27 January 2020

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps ⬇️

scientific article published on November 15, 2001

Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia

scientific article published on 30 June 2013

Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells.

scientific article

Nucleocytoplasmic Transport of RNAs and RNA-Protein Complexes.

scientific article published on October 2015

Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation.

scientific article

Post-mitotic dynamics of pre-nucleolar bodies is driven by pre-rRNA processing

scientific article

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

scientific article published on 24 October 2018

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes.

scientific article published on 8 March 2018

RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature

scientific article published on 17 October 2019

RPS19 mutations in patients with Diamond-Blackfan anemia

scientific article

Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.

scientific article published on 29 March 2018

Ribosomal 60S-subunit production: the final scene

scientific article published on 01 November 2015

Ribosomal Protein Genes RPS10 and RPS26 Are Commonly Mutated in Diamond-Blackfan Anemia

article

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

scientific article

Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism

scientific article published on 01 January 2020

Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia

scientific article

Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing

scientific article

Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function

scientific article

Sequential protein association with nascent 60S ribosomal particles

scientific article

Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis

scientific article

Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing

scientific article published on 16 August 2016

The Genetic Landscape of Diamond-Blackfan Anemia

scientific article published on 29 November 2018

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.

scientific article

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

scientific article published on 01 January 2020

The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

scientific article published in Nature Communications

The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast

scientific article

Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.

scientific article

List of works by Pierre-Emmanuel Gleizes

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism ⬇️

An overview of pre-ribosomal RNA processing in eukaryotes

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.

Cell release of bioactive fibroblast growth factor 2 by exon 6-encoded sequence of vascular endothelial growth factor

Characterization of the lipid envelope of exosome encapsulated HEV particles protected from the immune response.

Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.

Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models.

Diamond Blackfan anemia: ribosomal proteins going rogue.

Diamond-Blackfan anemia reveals the dark side of ribosome biogenesis

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae

Germline mutation of RPS20, encoding a ribosomal protein, causes predisposition to hereditary nonpolyposis colorectal carcinoma without DNA mismatch repair deficiency

Good Vibrations: Structural Remodeling of Maturing Yeast Pre-40S Ribosomal Particles Followed by Cryo-Electron Microscopy

Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1.

Impaired ribosome biogenesis in Diamond-Blackfan anemia

Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models

Labeling of basic fibroblast growth factor with digoxigenin: a nonradioactive probe for biochemical and cytological applications.

Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae

Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation

Maturation of pre-40S particles in yeast and humans

Molecular approaches to diagnose Diamond-Blackfan anemia: The EuroDBA experience.

Molecular basis of Diamond Blackfan anemia: structure and function analysis of RPS19

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder

NHP2 deficiency impairs rRNA biogenesis and causes pulmonary fibrosis and Høyeraal-Hreidarsson syndrome

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps ⬇️

Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia

Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells.

Nucleocytoplasmic Transport of RNAs and RNA-Protein Complexes.

Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation.

Post-mitotic dynamics of pre-nucleolar bodies is driven by pre-rRNA processing

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes.

RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature

RPS19 mutations in patients with Diamond-Blackfan anemia

Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.

Ribosomal 60S-subunit production: the final scene

Ribosomal Protein Genes RPS10 and RPS26 Are Commonly Mutated in Diamond-Blackfan Anemia

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism

Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia

Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing

Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function

Sequential protein association with nascent 60S ribosomal particles

Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis

Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing

The Genetic Landscape of Diamond-Blackfan Anemia

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast

Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.