List of works - Natalia S. Pellegata

A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization ⬇️

scientific article published on November 1, 2010

A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.

scientific article

Acromegaly due to a Macroinvasive Plurihormonal Pituitary Adenoma and a Rectal Carcinoid Tumor

scientific article

Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome

scientific article

Analysis and clinical implications of K-ras gene mutations and infection with human papillomavirus types 16 and 18 in primary adenocarcinoma of the uterine cervix

scientific article published on 01 February 1995

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

scientific article

Animal models of multiple endocrine neoplasia

scientific article published on 13 July 2015

Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.

scientific article published on 11 June 2014

Characterization of MENX-associated pituitary tumours.

scientific article published in April 2013

Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.

scientific article

DNA damage and p53-mediated cell cycle arrest: a reevaluation.

scientific article published on December 1996

Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging

scientific article

Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.

scientific article

Folate receptor-mediated drug targeting: a possible strategy for nonfunctioning pituitary adenomas?

scientific article published in April 2013

Gene expression in papillary thyroid carcinoma reveals highly consistent profiles ⬇️

scientific article published on December 18, 2001

Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53

scientific article

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

scientific article

Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.

scientific article

Hashimoto's thyroiditis with papillary thyroid carcinoma (PTC)-like nuclear alterations express molecular markers of PTC.

scientific article

Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions

scientific article published on 07 June 2007

Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest.

scientific article

Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy

scientific article published on 2 September 2011

Intracellular versican expression in mesenchymal spindle cell tumors contrasts with extracellular expression in epithelial and other tumors--a tissue microarray-based study

scientific article published on 01 May 2008

Loss of heterozygosity and K-ras gene mutations in gastric cancer

scientific article published on 01 October 1993

Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.

scientific article published on 2 April 2016

MENX and MEN4 ⬇️

scientific article published on January 1, 2012

MENX.

scientific article published on 25 April 2012

Mapping of a novel MEN-like syndrome locus to rat Chromosome 4

scientific article published on 01 February 2004

Morphology, Biochemistry, and Pathophysiology of MENX-Related Pheochromocytoma Recapitulate the Clinical Features.

scientific article

Multiple Endocrine Neoplasia Type 4 ⬇️

scientific article published on March 19, 2013

Multiple endocrine neoplasia syndromes associated with mutation of p27.

scientific article published on 26 June 2013

Mutations in KERA, encoding keratocan, cause cornea plana

scientific article

Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity

scientific article

Oncogenic features of the bone morphogenic protein 7 (BMP7) in pheochromocytoma.

scientific article published on 18 August 2015

Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone

scientific article published in The Lancet

Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes

scientific article

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

scientific article

Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model

scientific article

Primary Cell Culture Systems for Human Thyroid Studies.

scientific article published on 13 June 2016

Primary retroperitoneal mucinous cystoadenocarcinomas: an immunohistochemical and molecular study.

scientific article

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary

scientific article published on 16 December 2014

Secretin Receptor Promotes the Proliferation of Endocrine Tumor Cells Via the PI3K/AKT Pathway ⬇️

scientific article published on June 12, 2012

Semiquantitative 123I-Metaiodobenzylguanidine Scintigraphy to Distinguish Pheochromocytoma and Paraganglioma from Physiologic Adrenal Uptake and Its Correlation with Genotype-Dependent Expression of Catecholamine Transporters.

scientific article published on 16 April 2015

Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomas

scientific article

Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas.

scientific article published on 2 April 2015

miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance

scientific article published on 28 August 2020

p27 variant and corticotropinoma susceptibility: a genetic and in vitro study.

scientific article published on 28 April 2014

p27kip1: a new multiple endocrine neoplasia gene?

scientific article published on 27 October 2010

List of works by Natalia S. Pellegata

A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization ⬇️

A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype.

Acromegaly due to a Macroinvasive Plurihormonal Pituitary Adenoma and a Rectal Carcinoid Tumor

Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome

Analysis and clinical implications of K-ras gene mutations and infection with human papillomavirus types 16 and 18 in primary adenocarcinoma of the uterine cervix

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

Animal models of multiple endocrine neoplasia

Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.

Characterization of MENX-associated pituitary tumours.

Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.

DNA damage and p53-mediated cell cycle arrest: a reevaluation.

Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging

Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region.

Folate receptor-mediated drug targeting: a possible strategy for nonfunctioning pituitary adenomas?

Gene expression in papillary thyroid carcinoma reveals highly consistent profiles ⬇️

Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.

Hashimoto's thyroiditis with papillary thyroid carcinoma (PTC)-like nuclear alterations express molecular markers of PTC.

Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions

Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest.

Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy

Intracellular versican expression in mesenchymal spindle cell tumors contrasts with extracellular expression in epithelial and other tumors--a tissue microarray-based study

Loss of heterozygosity and K-ras gene mutations in gastric cancer

Loss of p27 expression is associated with MEN1 gene mutations in sporadic parathyroid adenomas.

MENX and MEN4 ⬇️

MENX.

Mapping of a novel MEN-like syndrome locus to rat Chromosome 4

Morphology, Biochemistry, and Pathophysiology of MENX-Related Pheochromocytoma Recapitulate the Clinical Features.

Multiple Endocrine Neoplasia Type 4 ⬇️

Multiple endocrine neoplasia syndromes associated with mutation of p27.

Mutations in KERA, encoding keratocan, cause cornea plana

Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity

Oncogenic features of the bone morphogenic protein 7 (BMP7) in pheochromocytoma.

Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone

Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

Preclinical evaluation of 18F-LMI1195 for in vivo imaging of pheochromocytoma in the MENX tumor model

Primary Cell Culture Systems for Human Thyroid Studies.

Primary retroperitoneal mucinous cystoadenocarcinomas: an immunohistochemical and molecular study.

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary

Secretin Receptor Promotes the Proliferation of Endocrine Tumor Cells Via the PI3K/AKT Pathway ⬇️

Semiquantitative 123I-Metaiodobenzylguanidine Scintigraphy to Distinguish Pheochromocytoma and Paraganglioma from Physiologic Adrenal Uptake and Its Correlation with Genotype-Dependent Expression of Catecholamine Transporters.

Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomas

Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas.

miR-34a is upregulated in AIP-mutated somatotropinomas and promotes octreotide resistance

p27 variant and corticotropinoma susceptibility: a genetic and in vitro study.

p27kip1: a new multiple endocrine neoplasia gene?