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List of works by Tim Hucho

5-Fluorouracil affects assembly of stress granules based on RNA incorporation

scientific article published on 11 April 2014

A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability

scientific article published on 02 May 2018

A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation

scientific article

Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons

scientific article published on 9 February 2017

Ataxin-2-like is a regulator of stress granules and processing bodies

scientific article

Biallelic variants in YRDC cause a developmental disorder with progeroid features

scientific article published on 20 September 2021

Ca++/CaMKII switches nociceptor-sensitizing stimuli into desensitizing stimuli

scientific article published on 28 September 2012

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma.

scientific article

Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging.

scientific article published on 17 May 2017

Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α2δ-1 with thrombospondin-4

scientific article published on 07 November 2019

Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells

scientific article published on 12 August 2019

Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.

scientific article published in June 2005

Estrogen controls PKCepsilon-dependent mechanical hyperalgesia through direct action on nociceptive neurons

scientific article published on 12 July 2006

Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway

scientific article published on 13 May 2011

Evaluation of small intestinal damage in a rat model of 6 Minutes cardiac arrest.

scientific article

GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat.

scientific article published on 26 March 2008

Identification and characterisation of novel tubulin-binding motifs located within the C-terminus of TRPV1.

scientific article published on 9 February 2007

Impaired left-ventricular cardiac function in male GPR30-deficient mice.

scientific article published on 30 November 2010

Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells

scientific journal article

Mechanistic hierarchical population model identifies latent causes of cell-to-cell variability

Novel aspects of the submembraneous microtubule cytoskeleton

scientific article published on 27 August 2008

ODE constrained mixture modelling: a method for unraveling subpopulation structures and dynamics

scientific article

Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA

scientific article published on 03 September 2020

PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination.

scientific article published on 3 April 2018

Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons

scientific article published on 4 November 2013

Pericentromeric Satellite III transcripts induce etoposide resistance

scientific article published on 24 May 2021

Primary afferent second messenger cascades interact with specific integrin subunits in producing inflammatory hyperalgesia

scientific journal article

Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitization

scientific article

Regulation, cellular localization, and function of the p75 neurotrophin receptor (p75NTR) during the regeneration of facial motoneurons

scientific article

ST3GAL3 mutations impair the development of higher cognitive functions.

scientific article

Signaling pathways in sensitization: toward a nociceptor cell biology

scientific article

Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit

scientific article

Submembraneous microtubule cytoskeleton: biochemical and functional interplay of TRP channels with the cytoskeleton

scientific article published on 27 August 2008

Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice.

scientific article

TRPV1 acts as a synaptic protein and regulates vesicle recycling.

scientific article

TRPV1 expression-dependent initiation and regulation of filopodia.

scientific article published on 20 August 2007

The Cdkn1a Mouse as a Tool to Study p53-Mediated Tumor Suppression

article

The bromodomain protein BRD4 regulates splicing during heat shock

scientific article

Threshold-free population analysis identifies larger DRG neurons to respond stronger to NGF stimulation.

scientific article

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia.

scientific article published on 16 July 2013

[1 + 1 = 0. Reprogramming of nociceptors].

scientific article published in December 2014

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