List of works - Timothy Wai

A hemizygous SCO2 mutation in an early onset rapidly progressive, fatal cardiomyopathy

scientific article published on 09 June 2006

Gimap3 Regulates Tissue-Specific Mitochondrial DNA Segregation ⬇️

scientific article published on October 14, 2010

High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts

scientific article published on 20 May 2021

Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L

scientific article

Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements

scientific article

Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria

scientific article

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

scientific article

LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria.

scientific article

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

scientific article

Medicine. Sidestepping mutational meltdown

scientific article published on February 2008

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research

scientific article published on 14 December 2013

Mitochondrial DNA and the mammalian oocyte.

scientific article published on January 2007

Mitochondrial Dynamics and Metabolic Regulation.

scientific article

Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

publication published on 01 November 2021

Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism

scientific article

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

scientific article published on 6 August 2015

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.

scientific article published on 16 March 2015

The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis

scientific journal article

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

scientific article (publication date: 17 March 2014)

The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.

scientific article published on 13 October 2016

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

scientific article

The role of mitochondrial DNA copy number in mammalian fertility.

scientific article

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

scientific article

List of works by Timothy Wai

A hemizygous SCO2 mutation in an early onset rapidly progressive, fatal cardiomyopathy

Gimap3 Regulates Tissue-Specific Mitochondrial DNA Segregation ⬇️

High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts

Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L

Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements

Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria.

Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms

Medicine. Sidestepping mutational meltdown

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research

Mitochondrial DNA and the mammalian oocyte.

Mitochondrial Dynamics and Metabolic Regulation.

Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.

The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

The role of mitochondrial DNA copy number in mammalian fertility.

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission