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List of works by Marina S. Gorbatyuk

A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure.

scientific article

AAV Delivery of Wild-Type Rhodopsin Preserves Retinal Function in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa ⬇️

scientific article published on March 7, 2011

ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis.

scientific article published on 13 September 2016

Ablation of C/EBP homologous protein does not protect T17M RHO mice from retinal degeneration

scientific article

Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

scientific article published in January 2016

An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina

scientific article published on 18 December 2014

ER stress in retinal degeneration in S334ter Rho rats

scientific article

Gene delivery of wild-type rhodopsin rescues retinal function in an autosomal dominant retinitis pigmentosa mouse model.

scientific article published on January 2012

Glycosylation of rhodopsin is necessary for its stability and incorporation into photoreceptor outer segment discs.

scientific article published on 30 January 2015

Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degeneration

scientific article

Limited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa

scientific article (publication date: 2016)

Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice.

scientific article published on 28 March 2012

Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors

scientific article

Neuronatin Protein in Health and Disease.

scientific article

Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme.

scientific article published on November 2006

Suppression of mouse rhodopsin expression in vivo by AAV mediated siRNA delivery

scientific article

TNFa knockdown in the retina promotes cone survival in a mouse model of autosomal dominant retinitis pigmentosa.

scientific article published on 14 October 2016

Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration.

scientific article published in July 2015

Translational attenuation and retinal degeneration in mice with an active integrated stress response.

scientific article

Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats.

scientific article published on 06 April 2012

Unfolded protein response is activated in aged retinas ⬇️

scientific article

Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa

scientific article

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