List of works - Sjoerd Wanrooij

A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol

scientific article published on 01 February 2021

ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia

scientific article

Binding to G-quadruplex RNA activates the mitochondrial GTPase NOA1.

scientific article published on 08 August 2013

ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells

scientific article

Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.

scientific article published on 22 April 2007

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

scientific article (publication date: July 2001)

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

scholarly article

In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication

scientific article published on 23 October 2012

In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

scientific article (publication date: December 2014)

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

scientific article

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication

scientific article published on 01 January 2010

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

scientific article

Optimization of the expression, purification and polymerase activity reaction conditions of recombinant human PrimPol.

scientific article published on 13 September 2017

Photoactivated Colibactin Probes Induce Cellular DNA Damage

PrimPol is required for replication reinitiation after mtDNA damage

scientific article published on 9 October 2017

Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA

scientific article

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling

scientific article

What causes mitochondrial DNA deletions in human cells?

scientific article published on March 2008

List of works by Sjoerd Wanrooij

A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol

ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia

Binding to G-quadruplex RNA activates the mitochondrial GTPase NOA1.

ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells

Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication

In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

Optimization of the expression, purification and polymerase activity reaction conditions of recombinant human PrimPol.

Photoactivated Colibactin Probes Induce Cellular DNA Damage

PrimPol is required for replication reinitiation after mtDNA damage

Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling

What causes mitochondrial DNA deletions in human cells?