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List of works by Giovanni Luca Beretta

1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment

scientific article published on 8 March 2017

A new avenue toward androgen receptor pan-antagonists: C2 sterically hindered substitution of hydroxy-propanamides

scientific article published on 28 August 2014

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

scientific article

Atomic force microscopy study of DNA conformation in the presence of drugs

scientific article published on 30 September 2010

Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models

scientific article

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

scientific article published on 19 August 2013

Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.

scientific article published on December 2006

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

scientific article published on 25 February 2011

Defining targets of modulation of human tumor cell response to cisplatin.

scientific article published on 8 January 2008

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents

scientific article published on March 2013

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

scientific article published on July 2003

Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response

scientific article published on July 2005

Electron microscopy analysis of early localization of cisplatin in ovarian carcinoma cells.

scientific article published on September 2002

Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins

scientific article published in March 2004

Fhit Nuclear Import Following EGF Stimulation Sustains Proliferation of Breast Cancer Cells.

scientific article

Global gene expression of fission yeast in response to cisplatin.

scientific article published in September 2004

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

scientific article published on 31 December 2009

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison

scientific article

Interaction model for anthracycline activity against DNA topoisomerase II.

scientific article published in June 2004

Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs.

scientific article published on 3 July 2010

Methods for Elucidation of DNA-Anticancer Drug Interactions and their Applications in the Development of New Drugs.

scientific article published on 31 August 2016

Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.

scientific article published on 10 October 2017

Novel 20(S)-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent: a patent evaluation of WO2015048365 (A1).

scientific article published on 27 January 2016

Novel Insights into Targeting ATP-Binding Cassette Transporters for Antitumor Therapy ⬇️

scientific article published on January 1, 2011

Overactive IGF1/Insulin Receptors and NRASQ61R Mutation Drive Mechanisms of Resistance to Pazopanib and Define Rational Combination Strategies to Treat Synovial Sarcoma

scientific article published on 22 March 2019

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

scientific article published on 3 August 2017

Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements

scientific article published on May 2016

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

scientific article published on 9 November 2006

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

scientific article

Proteomic analysis of cellular response to novel proapoptotic agents related to atypical retinoids in human IGROV-1 ovarian carcinoma cells

scientific article published on 18 January 2011

Reactivity of histidyl residues in D-amino acid oxidase from Rhodotorula gracilis

scientific article published on 01 April 1995

Redox-Sensitive PEG-Polypeptide Nanoporous Particles for Survivin Silencing in Prostate Cancer Cells

scientific article

Relevance of extracellular and intracellular interactions of camptothecins as determinants of antitumor activity.

scientific article published on 3 May 2007

Role of FoxO Proteins in Cellular Response to Antitumor Agents

scientific article published on 14 January 2019

Role of proliferation in HER2 status predicted response to doxorubicin.

scientific article published in July 2003

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

scientific article published on 29 September 2011

Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.

scientific article

Structural Requirements of Benzofuran Derivatives Dehydro-δ- and Dehydro-ε-Viniferin for Antimicrobial Activity Against the Foodborne Pathogen Listeria monocytogenes

scientific article published on 21 March 2020

Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach

scientific article published on December 2010

Sulfonates-PMMA nanoparticles conjugates: a versatile system for multimodal application

scientific article

Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.

scientific article published on 19 December 2016

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

scientific article published on 25 December 2007

Synthesis and cytotoxic activity of new 9-substituted camptothecins

scientific article published on 10 April 2008

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

scientific article published on August 2006

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

scientific article published on June 2004

Synthesis and cytotoxic activity of substituted luotonin A derivatives

scientific article

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

scientific article

Synthesis of new cytotoxic E-ring modified camptothecins

Targeting DNA topoisomerase I with non-camptothecin poisons.

scientific article published on January 2012

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

scientific article published on 16 June 2016

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

scientific article

Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors

scientific article published on 9 September 2008

The ABC of glycosylation

scientific article published on 10 June 2010

The Role of Polyamine Architecture on the Pharmacological Activity of Open Lactone Camptothecin−Polyamine Conjugates

scholarly article by Cristian Samorì et al published 18 March 2009 in Bioconjugate Chemistry

The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates

scientific article published on November 2008

Thiocamptothecin

scientific article published on 18 April 2008

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

scientific article published on January 2010

Unravelling "off-target" effects of redox-active polymers and polymer multilayered capsules in prostate cancer cells

scientific article

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

scientific article

miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis

scientific article published on 5 March 2017

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