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List of works by Marie-Pierre Gratacap

A confocal-based morphometric analysis shows a functional crosstalk between the actin filament system and microtubules in thrombin-stimulated platelets

scientific article published on 01 January 2013

A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation.

scientific article

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth.

scientific article

Class I PI 3-kinases signaling in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact of PTEN and SHIP1.

scientific article published on 18 September 2013

Class I PI3Ks in arterial thrombosis

scientific article published on 01 February 2019

Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets

scientific article published on 14 August 2002

Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

scientific article

Deletion of the p110 isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

scientific article published on 11 January 2010

Different roles of SHIP1 according to the cell context: the example of blood platelets.

scientific article

Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides.

scientific article

Essential role of class II PI3K-C2α in platelet membrane morphology

scientific article

Expression of myotubularins in blood platelets: Characterization and potential diagnostic of X-linked myotubular myopathy.

scientific article published on 4 May 2016

Flavonoids and the inhibition of PKC and PI 3-kinase

scientific article

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

scientific journal article

Kinetics of mean platelet volume predicts mortality in patients with septic shock

scientific article published on 17 October 2019

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

scientific article

PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity

scientific article published on 20 April 2021

Phosphatidylinositol 3 monophosphate metabolizing enzymes in blood platelet production and in thrombosis

scientific article published on 07 October 2019

Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.

scientific article

Phosphoinositides: Important lipids in the coordination of cell dynamics

scientific article published on 18 September 2015

Phosphoinositides: key players in cell signalling, in time and space.

scientific article published in June 2001

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate.

scientific article published on 14 November 2014

Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

scientific article published in Scientific Reports

Platelets Are Critical Key Players in Sepsis ⬇️

scientific article published on 16 July 2019

Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia

scientific article

Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation

scientific article published on 12 June 2018

Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions

scientific article

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation

scientific journal article

Targeting Kinases in Cancer Therapies: Adverse Effects on Blood Platelets.

scientific article published on 26 February 2016

The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies

scientific article

The class I phosphoinositide 3-kinases α and β control antiphospholipid antibodies-induced platelet activation.

scientific article published on 28 January 2016

The importance of blood platelet lipid signaling in thrombosis and in sepsis.

scientific article published on 29 September 2017

The lipid products of phosphoinositide 3-kinase isoforms in cancer and thrombosis.

scientific article

The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo.

scientific article

The role of class I, II and III PI 3-kinases in platelet production and activation and their implication in thrombosis

scientific article published on 02 December 2015

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