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List of works by Charles Theillet

17q21-q25 aberrations in breast cancer: combined allelotyping and CGH analysis reveals 5 regions of allelic imbalance among which two correspond to DNA amplification

article

A Complex Network of Tumor Microenvironment in Human High-Grade Serous Ovarian Cancer

scientific article published on 2 October 2017

A gene expression signature that can predict the recurrence of tamoxifen-treated primary breast cancer

scientific article

A new molecular breast cancer subclass defined from a large scale real-time quantitative RT-PCR study

scientific article

A predictable conserved DNA base composition signature defines human core DNA replication origins

scientific article published on 21 September 2020

A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene

scientific article published on August 2003

A refined molecular taxonomy of breast cancer

scientific article published on 25 July 2011

Amplification of 11q13 DNA sequences in human breast cancer: D11S97 identifies a region tightly linked to BCL1 which can be amplified separately.

scientific article

Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas

article

Amplification of the BRCA2 Pathway Gene EMSY in Sporadic Breast Cancer Is Related to Negative Outcome

article

An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis

scientific article

An attempt to define sets of cooperating genetic alterations in human breast cancer

scientific article published on June 1992

An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

scientific article published on 01 April 2019

At least five regions of imbalance on 6q in breast tumors, combining losses and gains

scientific article published on 01 January 2000

Ataxia-telangiectasia and cancer: an open question

scientific article published on July 1997

BCL-1 participates in the 11q13 amplification found in breast cancer

BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers

Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse

scientific article published on 19 December 2013

CCND1 and FGFR1 coamplification results in the colocalization of 11q13 and 8p12 sequences in breast tumor nuclei.

scientific article published in August 1998

CD44 expression patterns in breast and colon tumors: a PCR-based study of splice variants

scientific article

CYP17 polymorphism in the groups of distinct breast cancer susceptibility: comparison of patients with the bilateral disease vs. monolateral breast cancer patients vs. middle-aged female controls vs. elderly tumor-free women.

scientific article

Cathepsin D assay in primary breast cancer and lymph nodes: Relationship with c-myc, c-erb-B-2 and int-2 oncogene amplification and node invasiveness

scientific article published on 01 April 1990

Characterization of the region of the short arm of chromosome 8 amplified in breast carcinoma.

scientific article

Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition.

scientific article published on 12 July 2017

Chordin is underexpressed in ovarian tumors and reduces tumor cell motility

scientific article

Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care

scientific article published on 4 February 2016

Circulating tumor cells: potential markers of minimal residual disease in ovarian cancer? a study of the OVCAD consortium.

scientific article published on 16 November 2017

Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene

scholarly article

Coamplification in human breast-tumors and physical linkage at chromosomal band 12p13, of ccnd2 and fgf6 genes

article

Comparative genomic hybridization analysis of breast tumors with predetermined profiles of DNA amplification

article

Comprehensive profiling of 8p11-12 amplification in breast cancer

scientific article published on December 2005

Concordance of allelic imbalance profiles in synchronous and metachronous bilateral breast carcinomas

scientific article published on August 2002

Concurrent abnormal expression of erbB-2, myc and ras genes is associated with poor outcome of ovarian cancer patients.

scientific article published on July 1995

Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters

scientific article published on 01 March 1998

Cyclin gene amplification and overexpression in breast and ovarian cancers: Evidence for the selection ofcyclin D1 in breast andcyclin E in ovarian tumors

article

D11S146 and BCL1 are physically linked but can be discriminated by their amplification status in human breast cancer

scientific article published on 01 June 1991

DNA amplification at 11q13 in human cancer: from complexity to perplexity

scientific article

DNA amplification at 11q13.5-q14 in human breast cancer

DNA amplifications at 20q13 and MDM2 define distinct subsets of evolved breast and ovarian tumours

scientific article

Decrease of c-erbB-2 and c-myc RNA levels in tamoxifen-treated breast cancer.

scientific article published on March 1991

Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma

scientific article

Direct Sequencing by Thermal Asymmetric PCR

scientific article published on 01 January 2003

Direct Sequencing by Thermal Asymmetric PCR

scientific article published on 01 January 1996

Direct sequencing by thermal asymmetric PCR.

scientific article

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells

scientific article published on 10 June 2019

Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells

Distinct prevalence of the CYP19 Δ3(TTTA)7 allele in premenopausal versus postmenopausal breast cancer patients, but not in control individuals

article

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

scientific article (publication date: 26 November 2003)

Estrogen and retinoic acid antagonistically regulate several microRNA genes to control aerobic glycolysis in breast cancer cells

scientific article

Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation

scientific article published on April 2004

Evidence for microsatellite instability in bilateral breast carcinomas

article

FGFRI andPLAT genes and DNA amplification at 8p 12 in breast and ovarian cancers

article

Full speed ahead for tumor screening ⬇️

scientific article published on 01 July 1998

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas

scientific article published on July 1986

Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q

scientific article published on 24 October 2006

Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications

scientific article

Genetic variability of proto-oncogenes for breast cancer risk and prognosis

scientific article published on July 1988

Genomic and expression profiling of chromosome 17 in breast cancer reveals complex patterns of alterations and novel candidate genes

scientific article published on September 2004

Genomic markers for ovarian cancer at chromosomes 1, 8 and 17 revealed by array CGH analysis

scientific article published in May 2009

Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522.

scientific article published on December 1994

Growth factor requirement, oncogene expression and TP53 mutations of a tumorigenic and a non-tumorigenic subline of the human breast carcinoma cell line, HMT-3909.

scientific article published on January 1995

High Frequency of Rare Alleles of the Human c-Ha-ras-1 Proto-oncogene in Breast Cancer Patients2

article

Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors

scientific article published on 01 May 2000

Human gp130 transducer chain gene (IL6ST) is localized to chromosome band 5q11 and possesses a pseudogene on chromosome band 17p11

scientific article

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

scientific article published on 04 February 2019

Impact of chromosomal instability on colorectal cancer progression and outcome

scientific article

In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity

article

In situ c-myc expression and genomic status of the c-myc locus in infiltrating ductal carcinomas of the breast

scientific article published on 01 January 1988

In situ detection of c-myc mRNA in adenocarcinomas, adenomas, and mucosa of human colon

scientific article published in 1989

Independent prognostic value of somatic TP53 gene mutations in 1794 breast cancer patients.

scientific article published on 17 June 2005

Influence of the excision shock on the protein metabolism ofVicia faba L. meristematic root cells.

scientific article

International network of cancer genome projects

scientific article

Involvement ofATMmissense variants and mutations in a series of unselected breast cancer cases

Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles

scientific article

Localization of 11q13 loci with respect to regional chromosomal breakpoints

scientific article published on April 1992

Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas

scientific article published on 01 September 1986

Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors

article

Loss of heterozygosity in human breast carcinomas in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions

article

Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: possibly four regions of deletion

MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network model

scientific article

MYEOV: A candidate gene for DNA amplification events occurring centromeric toCCND1in breast cancer

article

Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups

scientific article published on 01 October 1997

Modeling risk stratification in human cancer

scientific article

Molecular analysis of the IL-6 receptor in human multiple myeloma, an IL-6-related disease

article

Molecular cytogenetic analysis of breast cancer cell lines

scientific article published on November 2000

Multiple sites of loss of heterozygosity on chromosome arms 3p and 3q in human breast carcinomas

scientific article published on 01 March 1996

Mutation of the Tumor Suppressor Gene TP53 Is Not Detected in Psoriatic Skin

article

Mutations of the p53 gene in human myeloma cell lines

scientific article published on May 1992

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

scientific article

Nucleotide sequence polymorphism in a hotspot mutation region of the p53 gene

article

Oncogenes, anti-oncogenes and their alterations in human tumors

scientific article

Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure

scientific article

PAIR-gynaecology: multi/interdisciplinary for gynecologic cancer research. Problems needed to be resolved

scientific article

Patterns of allele losses suggest the existence of five distinct regions of loh on chromosome 17 in breast cancer

scientific article published on 01 January 1994

Patterns of dna amplification at band q13 of chromosome 11 in human breast cancer

article

Presence of an allelic EcoRI restriction fragment of the c-mos locus in leukocyte and tumor cell DNAs of breast cancer patients

scientific article published on October 1985

Prognostic significance of TRIM24/TIF-1α gene expression in breast cancer.

scientific article

Proto-oncogene amplification and human breast tumor phenotype

scientific article published on 01 November 1989

Protocols for an improved detection of point mutations by SSCP

scientific article

Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene

scientific article

Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia

scientific article published in Science

Relating genotype and phenotype in breast cancer: an analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations

article

Relative efficiency of denaturing gradient gel electrophoresis and single strand conformation polymorphism in the detection of mutations in exons 5 to 8 of the p53 gene

article

Relaxed cell-cycle arrests and propagation of unrepaired chromosomal damage in cancer cell lines with wild-type p53

scientific article published on 01 September 1998

Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer

scientific article published on 08 September 2013

Slug/Pcad pathway controls epithelial cell dynamics in mammary gland and breast carcinoma.

scientific article

Snail and slug play distinct roles during breast carcinoma progression.

scientific article published in September 2006

Stable amino-acid sequence of the Mannose-6-phosphate/insulin-like growth-factor-II receptor in ovarian carcinomas with loss of heterozygosity and in breast-cancer cell lines

scientific article published on 01 February 2000

Structure and chromosomal assignment to 22q12 and 17qter of the ras-related Rac2 and Rac3 human genes

scientific article

TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.

scientific article

TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains.

scientific article published in September 1995

Targeting homologous repair deficiency in breast and ovarian cancers: Biological pathways, preclinical and clinical data

scientific article published on 05 November 2018

Targeting triple-negative breast cancer and high-grade ovarian carcinoma: refining BRCAness beyond BRCA1/2 mutations?

scientific article published in February 2015

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

scientific article

Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis

scientific article

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

scientific article

Transcription Factor Networks derived from Breast Cancer Stem Cells control the immune response in the Basal subtype.

scientific article

Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6

scientific article

What do we learn from HER2-positive breast cancer genomic profiles?

scientific article published on June 2010

[Genes and cancer. CHK2 (CDS1, Rad53): tumor suppressor gene]

scientific article published on 01 July 2003

[Genetic profiling of cancer: what for and when?]

scientific article

[P53 genes and solid tumors]

scientific article published on 01 August 1993

[Towards an inventory of oncogenic mutations in cancer]

scientific article published on 01 November 2010

[p53 mutations and human solid tumors]

scientific article published on 01 January 1993

miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers

scientific article

p53 and RAS gene mutations in multiple myeloma

article

p53 gene mutations in human epithelial skin cancers

scientific article

p53 immunohistochemical analysis in breast cancer with four monoclonal antibodies: comparison of staining and PCR-SSCP results.

scientific article

p53 mutations in breast cancer: incidence and relations to tumor aggressiveness and evolution of the disease

scientific article published on 01 December 1997

p53 mutations in ovarian cancer: a late event?

scientific article published on 01 September 1991

p53 mutations occur in aggressive breast cancer

scientific article published on 01 July 1992

ras gene alterations and enhanced levels of ras p21 expression in a spectrum of benign and malignant human mammary tissues

scientific article published on December 1986

ras, p53 and HPV status in benign and malignant prostate tumors

scientific article published in April 1995

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