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Authors whose works are in public domain in at least one jurisdiction

List of works by Koichiro Ishimori

"Module" substitution in hemoglobin subunits. Preparation and characterization of a "chimera beta alpha-subunit"

scientific article published on 01 July 1994

'Module'-substituted globins: artificial exon shuffling among myoglobin, hemoglobin alpha- and beta-subunits.

scientific article

A Dye-Decolorizing Peroxidase from Vibrio cholerae

scientific article

A heme degradation enzyme, HutZ, from Vibrio cholerae

scientific article published on 24 May 2012

A single mutation converts Alr5027 from cyanobacteria Nostoc sp. PCC 7120 to a heme-binding protein with heme-degrading ability

scientific article published on 09 November 2019

Absence of a detectable intermediate in the compound I formation of horseradish peroxidase at ambient temperature

scientific article

Accelerating structural life science by paramagnetic lanthanide probe methods

scientific article published on 28 March 2019

Activation mechanisms of transcriptional regulator CooA revealed by small-angle X-ray scattering

scientific article published on 01 August 2004

Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities

scientific article published in October 1991

Amorphous Aggregation of Cytochrome c with Inherently Low Amyloidogenicity Is Characterized by the Metastability of Supersaturation and the Phase Diagram.

scientific article published on 29 January 2016

Binding of CO at the Pro2 side is crucial for the activation of CO-sensing transcriptional activator CooA. (1)H NMR spectroscopic studies.

scientific article

C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers

scientific article published on 06 September 2021

Catalytic activities and structural properties of horseradish peroxidase distal His42 --> Glu or Gln mutant

scientific article published on 01 August 1997

Catalytic roles of the distal site asparagine-histidine couple in peroxidases

scientific article published on 01 November 1996

Cerebral oxygen utilization analyzed by the use of oxygen-17 and its nuclear magnetic resonance

scientific article

Collapse and search dynamics of apomyoglobin folding revealed by submillisecond observations of alpha-helical content and compactness.

scholarly article

Complete Genome Sequence of Staphylococcus arlettae Strain P2, Isolated from a Laboratory Environment

scientific article published on 07 November 2019

Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.

scientific article published on 22 December 2015

Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering.

scientific article

Crystal structure of a protein with an artificial exon-shuffling, module M4-substituted chimera hemoglobin beta alpha, at 2.5 A resolution

scientific article

Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding

scientific article published on 21 July 2004

Cytoplasmic Heme-Binding Protein (HutX) from Vibrio cholerae Is an Intracellular Heme Transport Protein for the Heme-Degrading Enzyme, HutZ

scientific article

Decreased intracellular free magnesium in erythrocytes of spontaneously hypertensive rats.

scientific article published on March 1987

Design, construction, crystallization, and preliminary X-ray studies of a fine-tuning mutant (F133V) of module-substituted chimera hemoglobin

scientific article published on 01 August 1998

Detection of a Tryptophan Radical as an Intermediate Species in the Reaction of Horseradish Peroxidase Mutant (Phe-221 → Trp) and Hydrogen Peroxide ⬇️

scientific article published on June 12, 1998

Dioxygen reduction by bo-type quinol oxidase from Escherichia coli studied by submillisecond-resolved freeze-quench EPR spectroscopy.

scientific article published in March 2004

Direct observation of the multistep helix formation of poly-L-glutamic acids

scientific article published on 01 October 2002

Dual role of the active-center cysteine in human peroxiredoxin 1: Peroxidase activity and heme binding

scientific article published on 9 January 2017

Effects of intra- and intersubunit hydrogen bonds on the R-T transition in human hemoglobin as studied with alpha 42(C7) and beta 145(HC2) mutations.

scientific article

Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): conversion from His119/Cys170 coordination to His119/His171 coordination

scientific article published on 27 December 2011

Effects of the intramolecular disulfide bond on ligand binding dynamics in myoglobin.

scientific article

Electron transfer reaction in a single protein molecule observed by total internal reflection fluorescence microscopy.

scientific article published in February 2005

Electron transfer reactions in Zn-substituted cytochrome P450cam.

scientific article

Energetic Mechanism of Cytochrome c-Cytochrome c Oxidase Electron Transfer Complex Formation under Turnover Conditions Revealed by Mutational Effects and Docking Simulation.

scientific article

Energetic basis on interactions between ferredoxin and ferredoxin NADP+ reductase at varying physiological conditions

scientific article published on 25 November 2016

Functions of fluctuation in the heme-binding loops of cytochrome b5 revealed in the process of heme incorporation

scientific article published on 01 May 2000

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

scientific article published on 18 March 2016

Heme Binding to Porphobilinogen Deaminase from Vibrio cholerae Decelerates the Formation of 1-Hydroxymethylbilane

scientific article published on 23 January 2018

Heme-binding characteristics of the isolated PAS-A domain of mouse Per2, a transcriptional regulatory factor associated with circadian rhythms.

scientific article

Hierarchical folding mechanism of apomyoglobin revealed by ultra-fast H/D exchange coupled with 2D NMR.

scholarly article

High-pressure flash photolysis study of hemoprotein: effects of substrate analogues on the recombination of carbon monoxide to cytochrome P450CAM.

scientific article published on August 1994

HmuS from Yersinia pseudotuberculosis is a non-canonical heme-degrading enzyme to acquire iron from heme.

scientific article published on 3 April 2017

Hydrogen bond network in the distal site of peroxidases: spectroscopic properties of Asn70 --> Asp horseradish peroxidase mutant

scientific article published on 01 August 1997

Identification and functional and spectral characterization of a globin-coupled histidine kinase from Anaeromyxobacter sp. Fw109-5.

scientific article

Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2alpha kinase.

scientific article published on 12 December 2003

Identification of histidine 77 as the axial heme ligand of carbonmonoxy CooA by picosecond time-resolved resonance Raman spectroscopy

scientific article published on 01 October 2000

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

scientific article

Interaction of fully liganded valency hybrid hemoglobin with inositol hexaphosphate. Implication of the IHP-induced T state of human adult methemoglobin in the low-spin state

scientific article published on 01 November 1986

Investigation of the electron-transfer mechanism by cross-linking between Zn-substituted myoglobin and cytochrome b(5).

scientific article

Investigation of the redox-dependent modulation of structure and dynamics in human cytochrome c

scientific article

Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae

scientific article published on 29 March 2017

Isothermal titration calorimetric studies on the associations of putidaredoxin to NADH-putidaredoxin reductase and P450cam

scientific article published on 01 April 1998

Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding.

scientific article

Luminol activity of horseradish peroxidase mutants mimicking a proposed binding site for luminol in Arthromyces ramosus peroxidase

scientific article published on 01 August 1999

Mechanistic insights into heme-mediated transcriptional regulation via a bacterial manganese-binding iron regulator, iron response regulator (Irr)

scientific article published on 17 June 2020

Molecular basis of guanine nucleotide dissociation inhibitor activity of human neuroglobin by chemical cross-linking and mass spectrometry

scientific article published on 7 February 2007

Molecular mechanism of the electron transfer reaction in cytochrome P450(cam)--putidaredoxin: roles of glutamine 360 at the heme proximal site.

scientific article published in November 2002

NMR basis for interprotein electron transfer gating between cytochrome c and cytochrome c oxidase.

scientific article

NMR studies of putidaredoxin: associations of putidaredoxin with NADH-putidaredoxin reductase and cytochrome p450cam.

scientific article

NMR studies of recombinant cytochrome P450cam mutants

scientific article published on 01 January 1996

NMR study of human mutant hemoglobins synthesized in Escherichia coli. Consequences of tyrosine alpha 42 substitutions.

scientific article

NMR study of hybrid hemoglobins containing unnatural heme: effect of heme modification on their tertiary and quaternary structures

scientific article published on 01 August 1986

NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes.

scientific article published on 2 July 2003

NO-induced activation mechanism of the heme-regulated eIF2alpha kinase.

scientific article published in November 2002

Oligomerization of a molecular chaperone modulates its activity

scientific article

Osmotic pressure effects identify dehydration upon cytochrome c - cytochrome c oxidase complex formation contributing to a specific electron pathway formation

scientific article published on 06 April 2020

Oxidation-state-dependent protein docking between cytochrome c and cytochrome b(5): high-pressure laser flash photolysis study.

scientific article

Polyethylene glycol promotes autoxidation of cytochrome c.

scientific article published on 11 March 2018

Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine

scientific article published on 01 June 2011

Protein oxidation mediated by heme-induced active site conversion specific for heme-regulated transcription factor, iron response regulator

scientific article published on 5 January 2016

Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam.

scientific article

Reaction intermediates in the heme degradation reaction by HutZ from Vibrio cholerae

scientific article published on 13 June 2017

Redox-Dependent Dynamics in Heme-Bound Bacterial Iron Response Regulator (Irr) Protein

scientific article published on 5 July 2016

Redox-controlled backbone dynamics of human cytochrome c revealed by 15N NMR relaxation measurements

scientific article published on 19 June 2010

Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins.

scientific article published on 9 January 2018

Role of His63 in HutZ from Vibrio cholerae in the heme degradation reaction and heme binding

scientific article published on 01 April 2019

Role of conserved arginine in the heme distal site of HutZ from Vibrio cholerae in the heme degradation reaction

scientific article published on 02 November 2019

Roles of negatively charged surface residues of putidaredoxin in interactions with redox partners in p450cam monooxygenase system

scientific article

Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase

scientific article published on 01 January 1993

Roles of the axial push effect in cytochrome P450cam studied with the site-directed mutagenesis at the heme proximal site

scientific article published on 01 August 2000

Ruthenium-iron hybrid hemoglobins as a model for partially liganded hemoglobin: oxygen equilibrium curves and resonance Raman spectra

scientific article published on 01 October 1989

Sequence and temperature dependence of the end-to-end collision dynamics of single-stranded DNA

scientific article published on June 2013

Site-directed mutagenesis in haemoglobin. Functional role of tyrosine-42(C7) alpha at the alpha 1-beta 2 interface

scientific article published on 01 April 1991

Site-directed mutagenesis in hemoglobin: functional and structural role of inter- and intrasubunit hydrogen bonds as studied with 37 beta and 145 beta mutations

scientific article published on 01 March 1992

Site-directed mutagenesis in hemoglobin: functional and structural role of the penultimate tyrosine in the alpha subunit

scientific article published on 01 March 1994

Site-directed mutagenesis in hemoglobin: functional and structural study of the intersubunit hydrogen bond of threonine-38(C3)alpha at the alpha 1-beta 2 interface in human hemoglobin.

scientific article published on December 1993

Specific heme binding to heme regulatory motifs in iron regulatory proteins and its functional significance

scientific article published on 03 June 2019

Specifically collapsed intermediate in the early stage of the folding of ribonuclease A.

scientific article published in July 2005

Spectroscopic studies on HasA from Yersinia pseudotuberculosis.

scientific article published on 29 April 2014

Stepwise formation of alpha-helices during cytochrome c folding

scientific article published on 01 June 2000

Steric effects of isoleucine 107 on heme reorientation reaction in human myoglobin.

scientific article published in November 2004

Structural Characterization of Heme Environmental Mutants of CgHmuT that Shuttles Heme Molecules to Heme Transporters

scientific article published on 27 May 2016

Structural and functional characterization of "laboratory evolved" cytochrome P450cam mutants showing enhanced naphthalene oxygenation activity.

scientific article published in October 2004

Structural and functional effects of pseudo-module substitution in hemoglobin subunits. New structural and functional units in globin structure

scientific article published on 01 April 1998

Structural and functional roles of heme binding module in globin proteins: identification of the segment regulating the heme binding structure.

scientific article published in January 1998

Structural and functional roles of modules in hemoglobin. Substitution of module M4 in hemoglobin subunits

scientific article published on 01 November 1997

Structural basis for the heme transfer reaction in heme uptake machinery from Corynebacteria

scientific article published on 01 November 2019

Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.

scientific article published on 20 December 2004

Structural insight into proline / isomerization of unfolded proteins catalyzed by the trigger factor chaperone

scientific article published in Journal of Biological Chemistry

Structural roles of the highly conserved glu residue in the heme distal site of peroxidases.

scientific article

Structure and ligand binding properties of leucine 29(B10) mutants of human myoglobin.

scientific article published in June 1992

Substitution of the heme binding module in hemoglobin alpha- and beta-subunits. Implication for different regulation mechanisms of the heme proximal structure between hemoglobin and myoglobin

scientific article published on 01 April 2000

Subunit-subunit interactions play a key role in the heme-degradation reaction of HutZ from Vibrio cholerae

scientific article published on 01 March 2019

The Effects of Heme Pocket Hydrophobicity on the Ligand Binding Dynamics in Myoglobin as Studied with Leucine 29 Mutants ⬇️

scientific article published on November 28, 1997

The Iron Chaperone Protein CyaY from Vibrio cholerae Is a Heme-Binding Protein

scientific article published on 24 April 2017

The artificial alpha1beta1-contact mutant hemoglobin, Hb Phe-35beta, shows only small functional abnormalities

scientific article published on 01 December 1998

The distal glutamic acid as an acid-base catalyst in the distal site of horseradish peroxidase

scientific article published on 01 October 1996

Two heme binding sites are involved in the regulated degradation of the bacterial iron response regulator (Irr) protein.

scientific article published on 21 December 2004

Uncovering dehydration in cytochrome refolding from urea- and guanidine hydrochloride-denatured unfolded state by high pressure spectroscopy

scientific article published on 31 January 2019

Unique peroxidase reaction mechanism in prostaglandin endoperoxide H synthase-2: compound I in prostaglandin endoperoxide H synthase-2 can be formed without assistance by distal glutamine residue

scientific article published on 01 April 2007

Unusual heme binding in the bacterial iron response regulator protein: spectral characterization of heme binding to the heme regulatory motif

scientific article

Unusual pressure effects on ligand rebinding to the human myoglobin Leucine 29 mutants

scientific article published on 01 September 2000

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