List of works - Rohan Lewis

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta

scientific article published on 02 June 2021

A systems perspective on placental amino acid transport.

scientific article published on 7 September 2018

Comparison of L-serine uptake by human placental microvillous membrane vesicles and placental villous fragments.

scientific article published on 24 February 2010

Computational modelling of amino acid exchange and facilitated transport in placental membrane vesicles.

scientific article

Computational modelling of fatty acid transport in the human placenta.

scientific article

Computational modelling of placental amino acid transfer as an integrated system

scientific article published on April 2016

DNA methylation of amino acid transporter genes in the human placenta.

scientific article published on 31 October 2017

Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet

scientific article published in February 2004

Effect of maternal iron restriction during pregnancy on renal morphology in the adult rat offspring

scientific article published on 01 July 2003

Effects of maternal iron restriction in the rat on blood pressure, glucose tolerance, and serum lipids in the 3-month-old offspring.

scientific article published in May 2001

Effects of maternal iron restriction on placental vascularization in the rat

scientific article published on 01 July 2001

Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux

scholarly article by Emma M Lofthouse published in October 2018

Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast.

scientific article published on 4 January 2011

Fetal and placental glucose and amino acid uptake in the spontaneously hypertensive rat ⬇️

scientific article published on July 1, 1998

Fetal rat lung epithelium has a functional growth hormone receptor coupled to tyrosine kinase activity and insulin-like growth factor binding protein-2 production.

scientific article published in August 1998

Glucocorticoid activity in the fetal spontaneously hypertensive rat.

scientific article published in January 1998

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast.

scientific article

Heterodimeric amino acid transporters in the placenta--a workshop report

scientific article published on 01 April 2007

High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

scientific article published on 20 May 2020

Human placental villi contain stromal macrovesicles associated with networks of stellate cells

scientific article published on 11 September 2019

IFPA Meeting 2010 Workshops Report II: Placental pathology; trophoblast invasion; fetal sex; parasites and the placenta; decidua and embryonic or fetal loss; trophoblast differentiation and syncytialisation.

scientific article published on 13 January 2011

IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta

scientific article published on 28 November 2013

IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics; biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth an

scientific article

IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction.

scientific article published on 15 December 2017

Immune response gene profiles in the term placenta depend upon maternal muscle mass.

scientific article

In vivo kinetic study of materno-fetal fatty acid transfer in obese and normal weight pregnant women

scientific article published on 24 July 2019

Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms

scientific article published on 11 March 2015

L-serine uptake by human placental microvillous membrane vesicles.

scientific article published on 10 August 2006

Long-term programming of blood pressure by maternal dietary iron restriction in the rat.

scientific article

Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply

scientific article published on 14 December 2004

Maternal Factors Are Associated with the Expression of Placental Genes Involved in Amino Acid Metabolism and Transport

scientific article published on 14 December 2015

Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring ⬇️

scientific article published on 30 October 2019

Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses.

scientific article published on 23 September 2004

Measurement of housekeeping genes in human placenta

scientific article published on 12 October 2009

Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry

scientific article published on 01 June 2019

Modelling nutrient transfer based on 3D imaging of the human placental microstructure.

scientific article published in August 2016

Modelling the effect of intervillous flow on solute transfer based on 3D imaging of the human placental microstructure.

scientific article published on 12 October 2017

Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro

scientific article published on 15 July 2007

Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants

scientific article published on 01 August 2019

New perspectives on placental fatty acid transfer

scientific article published on 04 October 2018

Partitioning of glutamine synthesised by the isolated perfused human placenta between the maternal and fetal circulations

scientific article published on 23 October 2013

Perinatal Growth Disturbance in the Spontaneously Hypertensive Rat ⬇️

scientific article published on December 1, 1997

Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation.

scientific article published on 16 December 2015

Placental Composition and Surface Area but not Vascularization are Altered by Maternal Protein Restriction in the Rat

article

Placental Lipid and Fatty Acid Transfer in Maternal Overnutrition.

scientific article published on 17 March 2017

Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey.

scientific article published on 5 May 2015

Placental calcium transporter (PMCA3) gene expression predicts intrauterine bone mineral accrual

scientific article

Quantitated transcript haplotypes (QTH) ofAGTR1, reduced abundance of mRNA haplotypes containing 1166C (rs5186:A>C), and relevance to metabolic syndrome traits

article

Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women's survey

scientific article published on 24 December 2015

Relation of placental alkaline phosphatase expression in human term placenta with maternal and offspring fat mass

scientific article published on 13 June 2018

Review: Modelling placental amino acid transfer--from transporters to placental function.

scientific article

Review: Placenta, evolution and lifelong health.

scientific article published on 26 December 2011

Review: human placental oxygenation in late gestation: experimental and theoretical approaches

scientific article published on 26 January 2018

Serial block-face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast.

scientific article published on 17 July 2017

Serial block-face scanning electron microscopy reveals novel intercellular connections in human term placental microvasculature

scientific article published on 03 April 2020

Sex differences in the mRNA levels of housekeeping genes in human placenta

scientific article published on 15 April 2010

The influence of placental metabolism on fatty acid transfer to the fetus.

scientific article published on 02 December 2016

The mechanisms and regulation of placental amino acid transport to the human foetus.

scientific article published on 08 February 2008

The placental exposome: placental determinants of fetal adiposity and postnatal body composition

scientific article published on 08 October 2013

Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta

scientific article published on 16 November 2017

Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools.

scientific article published on 27 April 2011

Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta

scientific article published on 28 March 2019

What factors determine placental glucose transfer kinetics?

scientific article published on 22 July 2013

Whole organ vascular casting and microCT examination of the human placental vascular tree reveals novel alterations associated with pregnancy disease.

scientific article

List of works by Rohan Lewis

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta

A systems perspective on placental amino acid transport.

Comparison of L-serine uptake by human placental microvillous membrane vesicles and placental villous fragments.

Computational modelling of amino acid exchange and facilitated transport in placental membrane vesicles.

Computational modelling of fatty acid transport in the human placenta.

Computational modelling of placental amino acid transfer as an integrated system

DNA methylation of amino acid transporter genes in the human placenta.

Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet

Effect of maternal iron restriction during pregnancy on renal morphology in the adult rat offspring

Effects of maternal iron restriction in the rat on blood pressure, glucose tolerance, and serum lipids in the 3-month-old offspring.

Effects of maternal iron restriction on placental vascularization in the rat

Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux

Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast.

Fetal and placental glucose and amino acid uptake in the spontaneously hypertensive rat ⬇️

Fetal rat lung epithelium has a functional growth hormone receptor coupled to tyrosine kinase activity and insulin-like growth factor binding protein-2 production.

Glucocorticoid activity in the fetal spontaneously hypertensive rat.

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast.

Heterodimeric amino acid transporters in the placenta--a workshop report

High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

Human placental villi contain stromal macrovesicles associated with networks of stellate cells

IFPA Meeting 2010 Workshops Report II: Placental pathology; trophoblast invasion; fetal sex; parasites and the placenta; decidua and embryonic or fetal loss; trophoblast differentiation and syncytialisation.

IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta

IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics; biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth an

IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction.

Immune response gene profiles in the term placenta depend upon maternal muscle mass.

In vivo kinetic study of materno-fetal fatty acid transfer in obese and normal weight pregnant women

Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms

L-serine uptake by human placental microvillous membrane vesicles.

Long-term programming of blood pressure by maternal dietary iron restriction in the rat.

Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply

Maternal Factors Are Associated with the Expression of Placental Genes Involved in Amino Acid Metabolism and Transport

Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring ⬇️

Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses.

Measurement of housekeeping genes in human placenta

Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry

Modelling nutrient transfer based on 3D imaging of the human placental microstructure.

Modelling the effect of intervillous flow on solute transfer based on 3D imaging of the human placental microstructure.

Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro

Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants

New perspectives on placental fatty acid transfer

Partitioning of glutamine synthesised by the isolated perfused human placenta between the maternal and fetal circulations

Perinatal Growth Disturbance in the Spontaneously Hypertensive Rat ⬇️

Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation.

Placental Composition and Surface Area but not Vascularization are Altered by Maternal Protein Restriction in the Rat

Placental Lipid and Fatty Acid Transfer in Maternal Overnutrition.

Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey.

Placental calcium transporter (PMCA3) gene expression predicts intrauterine bone mineral accrual

Quantitated transcript haplotypes (QTH) ofAGTR1, reduced abundance of mRNA haplotypes containing 1166C (rs5186:A>C), and relevance to metabolic syndrome traits

Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women's survey

Relation of placental alkaline phosphatase expression in human term placenta with maternal and offspring fat mass

Review: Modelling placental amino acid transfer--from transporters to placental function.

Review: Placenta, evolution and lifelong health.

Review: human placental oxygenation in late gestation: experimental and theoretical approaches

Serial block-face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast.

Serial block-face scanning electron microscopy reveals novel intercellular connections in human term placental microvasculature

Sex differences in the mRNA levels of housekeeping genes in human placenta

The influence of placental metabolism on fatty acid transfer to the fetus.

The mechanisms and regulation of placental amino acid transport to the human foetus.

The placental exposome: placental determinants of fetal adiposity and postnatal body composition

Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta

Umbilical venous-arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools.

Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta

What factors determine placental glucose transfer kinetics?

Whole organ vascular casting and microCT examination of the human placental vascular tree reveals novel alterations associated with pregnancy disease.