List of works by Jacob Schachter

"Gloves-and-socks" melanoma: does histology make a difference?

scientific article published on 2 July 2008

90. Fecal Microbiota Transplantation in Metastatic Melanoma Patients Resistant to Anti-PD-1 Treatment

scholarly article by Ilan Youngster et al published 23 October 2019 in Open Forum Infectious Diseases

A comparative analysis of total serum miRNA profiles identifies novel signature that is highly indicative of metastatic melanoma: a pilot study

scientific article published on 29 July 2013

A longitudinal study of CEACAM1 expression in melanoma disease progression

scientific article published on 30 December 2014

A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme

scientific article published on 21 August 2015

A randomized controlled comparison of pembrolizumab and chemotherapy in patients with ipilimumab-refractory melanoma.

scientific article published on 15 January 2015

ADAR1 regulates melanoma cell invasiveness by controlling beta3-integrin via microRNA-30 family members

scientific article published on 01 August 2020

ADAR1-mediated regulation of melanoma invasion.

scientific article

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.

scientific article published on 10 September 2017

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial ⬇️

journal article from 'The Lancet Oncology' published in 2021

Adjuvant treatment for stage III melanoma in the era of targeted medicine and immunotherapy

Adoptive Cell Therapy for Metastatic Melanoma

scientific article published on January 2017

Adoptive T cell therapy: An overview of obstacles and opportunities.

scientific article

Adoptive T-cell transfer in melanoma

scientific article published on January 2013

Adoptive cell therapy for metastatic melanoma patients: pre-clinical development at the Sheba Medical Center

scientific article published on 01 March 2006

Adoptive cell therapy with autologous tumor-infiltrating lymphocytes and high-dose interleukin-2 for metastatic melanoma: The surgeon's perspective

scientific article

Adoptive immunotherapy of advanced melanoma

scientific article published on September 2012

Adoptive transfer of tumor-infiltrating lymphocytes for melanoma: new players, old game

scientific article published in June 2015

Adoptive transfer of tumor-infiltrating lymphocytes in patients with metastatic melanoma: intent-to-treat analysis and efficacy after failure to prior immunotherapies

scientific article

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system

scientific article published on 20 December 2018

Antitumour activity of pembrolizumab in advanced mucosal melanoma: a post-hoc analysis of KEYNOTE-001, 002, 006

scientific article published on 11 September 2018

Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials

scientific article published on 16 July 2020

CEACAM1 and MICA as novel serum biomarkers in patients with acute and recurrent pericarditis

scientific article published on 20 February 2016

CEACAM1 promotes melanoma cell growth through Sox-2.

scientific article

CT halo sign as an imaging marker for response to adoptive cell therapy in metastatic melanoma with pulmonary metastases

scientific article published on 26 March 2014

CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy

scientific article published on 24 March 2012

Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1) in posterior uveal melanoma: correlation with clinical and histological survival markers

scientific article published on 9 December 2011

Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients

scientific article

Clinical significance of pancreatic atrophy induced by immune checkpoint inhibitors: A case-control study

scientific article published on 01 October 2018

Collection of large-scale expanded lymphocyte cultures for adoptive immunotherapy using a COBE Spectra apheresis machine

scientific article published in July 2008

Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-positive melanoma (COMBI-v): results of a phase 3, o

article

Comprehensive single institute experience with melanoma TIL: Long term clinical results, toxicity profile, and prognostic factors of response

scientific article published on 06 April 2020

Concurrent chemobiotherapy with cisplatin, dacarbazine, decrescendo interleukin-2 and interferon alpha2b in patients with metastatic melanoma.

scientific article published in December 2008

Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma

scientific article published on 06 June 2019

Development of allogeneic NK cell adoptive transfer therapy in metastatic melanoma patients: in vitro preclinical optimization studies

scientific article

Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex

scientific article

Dynamic expression of protective CEACAM1 on melanoma cells during specific immune attack

scientific article

Early and late hematologic toxicity following CD19 CAR-T cells

scientific article published on 26 February 2019

Efficacy and safety of intravenous immunoglobulin in patients with metastatic melanoma

scientific article published on 01 September 2007

Eighth American Joint Committee on Cancer (AJCC) melanoma classification: Let us reconsider stage III.

scientific article published on 7 December 2017

Establishment and large-scale expansion of minimally cultured "young" tumor infiltrating lymphocytes for adoptive transfer therapy

scientific article published on March 2011

Establishment of adoptive cell therapy with tumor infiltrating lymphocytes for non-small cell lung cancer patients

scientific article published on 29 May 2018

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

scientific article published on 10 December 2020

Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma.

scientific article published on 26 September 2017

Final results of phase III SYMMETRY study: randomized, double-blind trial of elesclomol plus paclitaxel versus paclitaxel alone as treatment for chemotherapy-naive patients with advanced melanoma

scientific article

Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma

scientific article published on 02 September 2020

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

scientific article

Focus on adoptive T cell transfer trials in melanoma

scientific article

Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia

scientific article published on 02 July 2020

Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients.

scientific article

Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients

scientific article published on 01 March 2020

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma

scientific article

Histopathological expression analysis of intercellular adhesion molecule 1 (ICAM-1) along development and progression of human melanoma.

scientific article published on 14 September 2017

Immune co-culture cell microarray - a feasible tool for high-throughput functional investigation of lymphocyte-cancer interactions

scientific article published on 25 March 2020

Immunotherapy comes of age in octagenarian and nonagenarian metastatic melanoma patients

scientific article published on 14 January 2019

Immunotherapy for the management of advanced melanoma: the next steps

scientific article published on August 2013

Impaired platelet aggregation in melanoma patients treated with interferon-alpha-2b adjuvant therapy

scientific article published in February 2002

Improved overall survival in melanoma with combined dabrafenib and trametinib

scientific article

Increased serum NKG2D-ligands and downregulation of NKG2D in peripheral blood NK cells of patients with major burns

scientific article published on 29 December 2015

Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions

scientific article published on November 2006

Is the delay in starting postoperative radiotherapy a key factor in the outcome of advanced (T3 and T4) laryngeal cancer?

scientific article published on 01 October 2004

KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in <i>BRAF</i>-mutant melanoma

scientific article published on 01 December 2020

Locally produced CD19 CAR T cells leading to clinical remissions in medullary and extramedullary relapsed acute lymphoblastic leukemia

scientific article published on 26 September 2018

Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma

scientific article published on 23 December 2020

Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma

article

MDR1 expression identifies human melanoma stem cells.

scientific article published on 13 February 2008

Melanoma early detection and awareness: how countries developing melanoma awareness programs could benefit from melanoma-proficient countries

scientific article published on January 2015

Metastatic Lung Lesions as a Preferred Resection Site for Immunotherapy With Tumor Infiltrating Lymphocytes

scientific article published on 01 June 2016

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

scientific article published on June 2013

Minimally cultured or selected autologous tumor-infiltrating lymphocytes after a lympho-depleting chemotherapy regimen in metastatic melanoma patients

scientific article

Mutagen-specific mutation signature determines global microRNA binding

scientific article

Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells

scientific article

Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma

scientific article

Novel anti-melanoma immunotherapies: disarming tumor escape mechanisms

scientific article

Novel immunotherapy for malignant melanoma with a monoclonal antibody that blocks CEACAM1 homophilic interactions

scientific article

Older age and second skin cancer as prognostic factors in localized malignant melanomas

scientific article published on November 1, 2003

Open-label, multicentre safety study of vemurafenib in 3219 patients with BRAFV600 mutation-positive metastatic melanoma: 2-year follow-up data and long-term responders' analysis.

scientific article

Outcome of thick (> 4 mm) node-negative melanomas

scientific article

Patient-reported outcomes in patients with resected, high-risk melanoma with BRAFV600E or BRAFV600K mutations treated with adjuvant dabrafenib plus trametinib (COMBI-AD): a randomised, placebo-controlled, phase 3 trial

scientific article published on 27 March 2019

Patterns of failure in patients with malignant melanoma treated with high-dose interferon-alpha2b in the adjuvant setting

scientific article published on 01 February 2003

Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629)

scientific article published on 16 July 2020

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

scientific article

Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006).

scientific article

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study

scientific article published on 22 July 2019

Perioperative BRAF inhibitors in locally advanced stage III melanoma.

scientific article published on 26 June 2017

Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma

scientific article

Pigmented lesions clinic for early detection of melanoma: preliminary results.

scientific article

Pooled Analysis Safety Profile of Nivolumab and Ipilimumab Combination Therapy in Patients With Advanced Melanoma.

scientific article published on 15 September 2017

Possible immune adverse events as predictors of durable response to BRAF inhibitors in patients with BRAF V600-mutant metastatic melanoma

scientific article published on 07 August 2018

Preclinical evaluation of adoptive cell therapy for patients with metastatic renal cell carcinoma

scientific article published on 01 January 2009

Predicting and controlling the reactivity of immune cell populations against cancer

scientific article published on 28 April 2009

Predictors of tumor-infiltrating lymphocyte efficacy in melanoma

scientific article

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

scientific article published on 05 September 2019

Ras oncoproteins transfer from melanoma cells to T cells and modulate their effector functions.

scientific article

Real World Outcomes of Ipilimumab and Nivolumab in Patients with Metastatic Melanoma

scientific article published on 18 August 2020

Recurrent Pneumonitis in Patients with Melanoma Treated with Immune Checkpoint Inhibitors

scientific article published on 18 February 2019

Regulation of CEACAM1 Protein Expression by the Transcription Factor ETS-1 in BRAF-Mutant Human Metastatic Melanoma Cells.

scientific article published on 17 March 2018

Regulation of cancer aggressive features in melanoma cells by microRNAs

scientific article

Reply to E. Hindié and K.R. Hess

scientific article published on 02 April 2019

Rheumatic manifestations among cancer patients treated with immune checkpoint inhibitors

scientific article published on 13 January 2018

SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells

scientific article published on 14 February 2016

Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation

scientific article

Selumetinib in Combination With Dacarbazine in Patients With Metastatic Uveal Melanoma: A Phase III, Multicenter, Randomized Trial (SUMIT).

scientific article published on 12 March 2018

Sentinel node guided surgery for melanoma in the head and neck region

scientific article published in August 2004

Systemic dysregulation of CEACAM1 in melanoma patients

scientific article published on 01 February 2010

TNFSF4 (OX40L) expression and survival in locally advanced and metastatic melanoma

scientific article published on 09 September 2019

The non-responding adrenal metastasis in melanoma: The case for minimally invasive adrenalectomy in the age of modern therapies

scientific article published on 26 November 2019

Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials

scientific article

Tissue Harvesting for Adoptive Tumor Infiltrating Lymphocyte Therapy in Metastatic Melanoma

scientific article published on 01 September 2019

Tumor-Infiltrating Lymphocytes: Clinical Experience

scientific article

Tumor-infiltrating lymphocytes from human prostate tumors reveal anti-tumor reactivity and potential for adoptive cell therapy

scientific article published on 11 October 2019

Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study.

scientific article

Who benefits most from adjuvant interferon treatment for melanoma?

scientific article published on January 2015

miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1.

scientific article published on June 2015

microRNA expression patterns in tumor infiltrating lymphocytes are strongly associated with response to adoptive cell transfer therapy

scientific article published on 17 November 2020

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