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List of works by Vincenzo Costanzo

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy

scientific article

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

scientific article

ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks

scientific article

ATM controls proper mitotic spindle structure

scientific article published on 6 February 2014

ATR and ATM regulate the timing of DNA replication origin firing

scientific article published on 27 June 2004

ATR checkpoint suppression by repetitive DNA.

scientific article published on 26 July 2016

ATR expands embryonic stem cell fate potential in response to replication stress

scientific article published on 12 March 2020

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

scientific article

An ATM and ATR dependent pathway targeting centrosome dependent spindle assembly

scientific article

An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63.

scientific article

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

scientific article (publication date: 2003)

Brca2, Rad51 and Mre11: Performing balancing acts on replication forks ⬇️

scientific article published on 06 September 2011

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

scientific journal article

Centromere Structure and Function

scientific article published on 01 January 2017

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

scientific article

Cep63 and cep152 cooperate to ensure centriole duplication

scientific article

Chromatin determinants impart camptothecin sensitivity

scientific article published on 7 April 2017

DNA replication and homologous recombination factors: acting together to maintain genome stability

scientific article published on 16 April 2013

Dealing with dangerous accidents: DNA double-strand breaks take centre stage. Symposium on Genome Instability and DNA Repair

scientific article published on 17 July 2009

Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns

scientific article

Epigenetic regulation of replication origin assembly: A role for histone H1 and chromatin remodeling factors

scientific article published on 09 November 2020

Exploring the links between cancer and placenta development

article

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

scientific article

Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection.

scientific article

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

scientific journal article

GEMC1 is a critical regulator of multiciliated cell differentiation

scientific article published on March 2016

GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication

scientific article

HMGA1 protein is a novel target of the ATM kinase

scientific article published on 8 September 2008

In ataxia-teleangiectasia betamethasone response is inversely correlated to cerebellar atrophy and directly to antioxidative capacity

scientific article published on June 2009

Mechanisms of replication fork protection: a safeguard for genome stability

scientific article published on 11 February 2012

Mismatch repair-dependent metabolism of O6-methylguanine-containing DNA in Xenopus laevis egg extracts

scientific article published on 4 February 2015

Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.

scientific article published on 12 January 2017

Mre11 assembles linear DNA fragments into DNA damage signaling complexes

scientific article

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

scientific article

Mta2 promotes Tipin-dependent maintenance of replication fork integrity

scientific article published on 15 May 2014

NCOA4 transcriptional coactivator inhibits activation of DNA replication origins

scientific article published on 05 June 2014

Notch is a direct negative regulator of the DNA-damage response

scientific article

Plx1 is required for chromosomal DNA replication under stressful conditions

scientific article

Polo-like kinase 1 reaches beyond mitosis--cytokinesis, DNA damage response, and development

scientific article

Protein Kinase A is required for chromosomal DNA replication

scientific article published on 01 August 1999

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

scientific article

RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

scientific article published on January 2012

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

scientific article published on 10 October 2010

Regulation of DNA replication by ATR: signaling in response to DNA intermediates

scientific article

Replication, checkpoint suppression and structure of centromeric DNA.

scientific article published on 28 November 2016

Responding to chromosomal breakage during M-phase: insights from a cell-free system

scientific article published on 14 July 2009

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

scientific article

Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit

scientific article published on 28 February 2007

SAMHD1 acts at stalled replication forks to prevent interferon induction

scientific article published in Nature

Single-strand DNA gaps trigger an ATR- and Cdc7-dependent checkpoint

scientific article

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

scientific article

Structure of human Cdc45 and implications for CMG helicase function

scientific article published on 18 May 2016

Studying DNA Replication Fork Stability in Xenopus Egg Extract

scientific article published on 01 January 2011

Studying essential DNA metabolism proteins in Xenopus egg extract

scientific article published in January 2016

Studying the DNA damage response using in vitro model systems

scientific article published on 23 May 2009

The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms

Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts

scholarly article

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion

scientific article

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

scientific article

Xenopus egg extract to study regulation of genome-wide and locus-specific DNA replication.

scientific article published on 17 January 2017

Xenopus laevis as Model System to Study DNA Damage Response and Replication Fork Stability.

scientific article published on 8 April 2017

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