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List of works by Liangyi Chen

A Frequency Domain SIM Reconstruction Algorithm Using Reduced Number of Images

scientific article published on 30 May 2018

A fast solution switching system with temperature control for single cell measurements.

scientific article published on 21 April 2011

A subcellular map of the human kinome

scientific article published on 14 May 2021

Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1

scientific article published 2006 in Biochemical and Biophysical Research Communications

Alterations of the Ca²⁺ signaling pathway in pancreatic beta-cells isolated from db/db mice.

scientific article

An optical method to evaluate both mass and functional competence of pancreatic α- and β-cells.

scientific article published on 12 May 2016

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

scientific article published on 28 September 2020

Caenorhabditis elegans ciliary protein NPHP-8, the homologue of human RPGRIP1L, is required for ciliogenesis and chemosensation

scientific article published on 13 June 2011

Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells.

scientific article published on 9 November 2014

Calcium transport mechanisms of PC12 cells.

scientific article published on 17 March 2008

Contribution of different mechanisms to pancreatic beta-cell hyper-secretion in non-obese diabetic (NOD) mice during pre-diabetes

scientific article published on 13 September 2011

Contributions of Intracellular Compartments to Calcium Dynamics: Implicating an Acidic Store

article

Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders.

scientific article

Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling.

scientific article published in October 2015

Different KChIPs compete for heteromultimeric assembly with pore-forming Kv4 subunits

scientific article published on June 2015

Different stimulatory opioid effects on intracellular Ca(2+) in SH-SY5Y cells.

scientific article

Dynamics of calcium clearance in mouse pancreatic beta-cells.

scientific article published in July 2003

E-syt1 Re-arranges STIM1 Clusters to Stabilize Ring-shaped ER-PM Contact Sites and Accelerate Ca Store Replenishment

scientific article published on 08 March 2019

Exocytosis, Endocytosis, and Their Coupling in Excitable Cells

scientific article

Extracellular ATP stimulates exocytosis via localized Ca(2+) release from acidic stores in rat pancreatic beta cells.

scientific article published in April 2006

Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice.

scientific article

Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy

scientific article published on 11 April 2018

From Micro to Macro: The Hierarchical Design in a Micropatterned Scaffold for Cell Assembling and Transplantation.

scientific article published on 7 November 2016

Functional expression of large-conductance Ca2+-activated potassium channels in lateral globus pallidus neurons.

scientific article published on 25 June 2010

High spatiotemporal resolution and low photo-toxicity fluorescence imaging in live cells and in vivo

scientific article published on 01 December 2019

Imaging Ca2+ nanosparks in heart with a new targeted biosensor.

scientific article

Imaging beta-cell mass and function in situ and in vivo.

scientific article published on 23 May 2013

In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

article

Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution

scientific article published on 02 March 2020

Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation

scientific article (publication date: 5 October 2007)

Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state

scientific article

Myosin IIa is critical for cAMP-mediated endothelial secretion of von Willebrand factor

scientific article published on 5 December 2017

On the stoichiometry of resting and activated CRAC channels.

scientific article published on January 2013

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia

scientific article published on 27 April 2020

Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe.

scientific article

Overcoming foreign-body reaction through nanotopography: Biocompatibility and immunoisolation properties of a nanofibrous membrane.

scientific article published on 15 June 2016

Pancreatic α and β cells are globally phase-locked

scientific article published on 3 December 2021

Paracrine Interactions Within Islets of Langerhans

scientific article published on April 13, 2012

Pentamethylquercetin generates beneficial effects in monosodium glutamate-induced obese mice and C2C12 myotubes by activating AMP-activated protein kinase

scientific article published on March 14, 2012

Protective effects of Ginkgo biloba extract on rats during cerebral ischemia/reperfusion.

scientific article published in September 2002

Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx

scientific article

Rab5-dependent autophagosome closure by ESCRT.

scientific article published on 22 April 2019

Rapid volumetric imaging with Bessel-Beam three-photon microscopy.

scientific article published on 29 March 2018

Role of H(abc) domain in membrane trafficking and targeting of syntaxin 1A

scientific article

Shadowless-illuminated variable-angle TIRF (siva-TIRF) microscopy for the observation of spatial-temporal dynamics in live cells

scientific article

Spatiotemporal detection and analysis of exocytosis reveal fusion "hotspots" organized by the cytoskeleton in endocrine cells.

scientific article

Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells

scientific article published on 5 February 2016

Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules

scientific article