List of works - Debbie McKenzie

14-3-3 and enolase abundances in the CSF of Prion diseased rats

scientific article published on 12 September 2018

Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy

scientific article published on June 2000

Adsorption of Pathogenic Prion Protein to Quartz Sand

scientific article published in April 2007

Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities

scientific article

Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.

scientific article published on 13 May 2015

Cellular prion protein distribution in the vomeronasal organ, parotid, and scent glands of white-tailed deer and mule deer

scientific article published on 01 December 2022

Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

scientific article published on September 2017

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.

scientific article

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie.

scientific article

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

scientific article published on 11 August 2017

Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes.

scientific article published on 29 April 2017

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation ⬇️

scientific article published on November 17, 2011

Dual MicroRNA to Cellular Prion Protein Inhibits Propagation of Pathogenic Prion Protein in Cultured Cells.

scientific article published on 29 March 2017

Emerging prion disease drives host selection in a wildlife population.

scientific article published on April 2012

Establishment and characterization of Prnp knockdown neuroblastoma cells using dual microRNA-mediated RNA interference

scientific article

Golden hamster embryonic genome activation occurs at the two-cell stage: correlation with major developmental changes

scientific article published on July 1, 1992

Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb).

scientific article

Identification of a putative calcium-binding protein as a dioxin-responsive gene in zebrafish and rainbow trout.

scientific article published in May 2003

Infectious prions accumulate to high levels in non proliferative C2C12 myotubes.

scientific article

Labeling of the scrapie-associated prion protein in vitro and in vivo

scientific article published in November 2004

Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age.

scientific article published on 25 August 2016

Long term rapamycin treatment improves mitochondrial DNA quality in aging mice.

scientific article published on 24 February 2018

Low copper and high manganese levels in prion protein plaques.

scientific article published on 11 February 2013

Meat and Bone Meal and Mineral Feed Additives May Increase the Risk of Oral Prion Disease Transmission ⬇️

scientific article published on January 1, 2011

Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice

scientific article published on 02 August 2019

Mitochondrial DNA deletion mutations: a causal role in sarcopenia.

scientific article

Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia.

scientific article

Mitochondrial biogenesis drives a vicious cycle of metabolic insufficiency and mitochondrial DNA deletion mutation accumulation in aged rat skeletal muscle fibers

scientific article

Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys.

scientific article

MtDNA point mutations are associated with deletion mutations in aged rat

scientific article published on 18 January 2005

Oral transmissibility of prion disease is enhanced by binding to soil particles

scientific article

Pathogenic prion protein is degraded by a manganese oxide mineral found in soils

scientific article published on 01 January 2009

Persistence of pathogenic prion protein during simulated wastewater treatment processes

scientific article published on July 2008

Potential Role of Soil in the Transmission of Prion Disease

article

Potential role of soil properties in the spread of CWD in western Canada.

scientific article published on January 2014

Predicting the spread-risk potential of chronic wasting disease to sympatric ungulate species

scientific article published on 01 December 2020

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species.

scientific article

Prion disease tempo determined by host-dependent substrate reduction

scientific article published on 16 January 2014

Prion protein gene heterogeneity in free-ranging white-tailed deer within the chronic wasting disease affected region of Wisconsin ⬇️

scientific article published on July 1, 2003

Prion protein polymorphisms affect chronic wasting disease progression

scientific article

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP deposition in orally infected white-tailed deer

scientific article published on 04 February 2019

Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease

scientific article published on 01 July 2006

Prion strain mutation determined by prion protein conformational compatibility and primary structure

scientific article

Rebuttal to Jacobs: the mitochondrial theory of aging: alive and well

scientific article published on 01 February 2003

Replication of prions in differentiated muscle cells

scientific article published on 11 February 2014

Reversibility of scrapie inactivation is enhanced by copper

scientific article published in October 1998

Sequence homologtes in the protamine gene family of rainbow trout ⬇️

scientific article published on July 25, 1983

Soil humic acids degrade CWD prions and reduce infectivity

scholarly article published by Alsu Kuznetsova in 2018

Strain-specific propagation of PrP(Sc) properties into baculovirus-expressed hamster PrP(C).

scientific article published on October 2000

The host range of chronic wasting disease is altered on passage in ferrets

scientific article published in November 1998

The standard scrapie cell assay: development, utility and prospects

scientific article

Toll-like receptor-mediated immune response inhibits prion propagation.

scientific article

Transcriptomic responses to prion disease in rats

scientific article published on 5 September 2015

Transport of the pathogenic prion protein through landfill materials

scientific article published on March 2009

Transport of the pathogenic prion protein through soils

scientific article

Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity

scientific article published on 6 July 2009

List of works by Debbie McKenzie

14-3-3 and enolase abundances in the CSF of Prion diseased rats

Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy

Adsorption of Pathogenic Prion Protein to Quartz Sand

Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities

Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.

Cellular prion protein distribution in the vomeronasal organ, parotid, and scent glands of white-tailed deer and mule deer

Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie.

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes.

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation ⬇️

Dual MicroRNA to Cellular Prion Protein Inhibits Propagation of Pathogenic Prion Protein in Cultured Cells.

Emerging prion disease drives host selection in a wildlife population.

Establishment and characterization of Prnp knockdown neuroblastoma cells using dual microRNA-mediated RNA interference

Golden hamster embryonic genome activation occurs at the two-cell stage: correlation with major developmental changes

Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb).

Identification of a putative calcium-binding protein as a dioxin-responsive gene in zebrafish and rainbow trout.

Infectious prions accumulate to high levels in non proliferative C2C12 myotubes.

Labeling of the scrapie-associated prion protein in vitro and in vivo

Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age.

Long term rapamycin treatment improves mitochondrial DNA quality in aging mice.

Low copper and high manganese levels in prion protein plaques.

Meat and Bone Meal and Mineral Feed Additives May Increase the Risk of Oral Prion Disease Transmission ⬇️

Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice

Mitochondrial DNA deletion mutations: a causal role in sarcopenia.

Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia.

Mitochondrial biogenesis drives a vicious cycle of metabolic insufficiency and mitochondrial DNA deletion mutation accumulation in aged rat skeletal muscle fibers

Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys.

MtDNA point mutations are associated with deletion mutations in aged rat

Oral transmissibility of prion disease is enhanced by binding to soil particles

Pathogenic prion protein is degraded by a manganese oxide mineral found in soils

Persistence of pathogenic prion protein during simulated wastewater treatment processes

Potential Role of Soil in the Transmission of Prion Disease

Potential role of soil properties in the spread of CWD in western Canada.

Predicting the spread-risk potential of chronic wasting disease to sympatric ungulate species

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species.

Prion disease tempo determined by host-dependent substrate reduction

Prion protein gene heterogeneity in free-ranging white-tailed deer within the chronic wasting disease affected region of Wisconsin ⬇️

Prion protein polymorphisms affect chronic wasting disease progression

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP deposition in orally infected white-tailed deer

Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease

Prion strain mutation determined by prion protein conformational compatibility and primary structure

Rebuttal to Jacobs: the mitochondrial theory of aging: alive and well

Replication of prions in differentiated muscle cells

Reversibility of scrapie inactivation is enhanced by copper

Sequence homologtes in the protamine gene family of rainbow trout ⬇️

Soil humic acids degrade CWD prions and reduce infectivity

Strain-specific propagation of PrP(Sc) properties into baculovirus-expressed hamster PrP(C).

The host range of chronic wasting disease is altered on passage in ferrets

The standard scrapie cell assay: development, utility and prospects

Toll-like receptor-mediated immune response inhibits prion propagation.

Transcriptomic responses to prion disease in rats

Transport of the pathogenic prion protein through landfill materials

Transport of the pathogenic prion protein through soils

Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity