List of works by Gilean McVean

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A common sequence motif associated with recombination hot spots and genome instability in humans

A fine-scale chimpanzee genetic map from population sequencing

scientific article

A genealogical interpretation of linkage disequilibrium

scientific article published on October 2002

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

A model-based approach to capture genetic variation for future association studies

scientific article

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

scientific article published on January 2013

A second generation human haplotype map of over 3.1 million SNPs

scientific article

A unified genealogy of modern and ancient genomes

scientific article published on 25 February 2022

A unified genealogy of modern and ancient genomes

preprint

Accounting for long-range correlations in genome-wide simulations of large cohorts

scientific article published on 05 May 2020

Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors

scientific article

Adaptation and conflict : the differences between the sexes in mammalian genome evolution

DPhil Thesis of Gilean McVean

An insight into the genetic variation of Schistosoma japonicum in mainland China using DNA microsatellite markers.

scientific article

An integrated map of genetic variation from 1,092 human genomes

scientific article

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

Approximating the coalescent with recombination

scientific article published in July 2005

Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters

scientific article published on 22 September 2013

Bayesian meta-analysis across genome-wide association studies of diverse phenotypes

scientific article published on 28 March 2019

Bayesian refinement of association signals for 14 loci in 3 common diseases

scientific article published on 28 October 2012

Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA.

scientific article published on September 2017

Class II HLA interactions modulate genetic risk for multiple sclerosis

scientific article published on 07 September 2015

Classic selective sweeps were rare in recent human evolution

scientific article

Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis

scientific article published on 25 January 2014

Comparison of fine-scale recombination rates in humans and chimpanzees.

scientific article published on 10 February 2005

Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline

scientific article

Dating genomic variants and shared ancestry in population-scale sequencing data

Dating genomic variants and shared ancestry in population-scale sequencing data

scientific article published on 17 January 2020

De novo assembly and genotyping of variants using colored de Bruijn graphs

scientific article published on 8 January 2012

Detecting novel associations in large data sets

scientific article

Differential confounding of rare and common variants in spatially structured populations

scientific article published on 5 February 2012

Dindel: accurate indel calls from short-read data

scientific article

Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

scientific article

Elucidating relationships between P.falciparum prevalence and measures of genetic diversity with a combined genetic-epidemiological model of malaria

scientific article published on 19 August 2021

Erratum

Erratum: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

scientific article published in June 2013

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Estimating diversifying selection and functional constraint in the presence of recombination

scientific article

Estimating recombination rates from genetic variation in humans

scientific article published on January 2012

Estimating recombination rates from population-genetic data

scientific article

Estimating selection coefficients in spatially structured populations from time series data of allele frequencies

scientific article

Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line

scientific article

Evidence for widespread cryptic sexual generations in apparently purely asexual Andricus gallwasps

scientific article published on 12 December 2007

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia

scientific article

Genetic architecture of artemisinin-resistant Plasmodium falciparum

scientific article (publication date: March 2015)

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.

scientific article published on 10 April 2017

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide detection and characterization of positive selection in human populations

scientific article

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.

scientific article

Genomewide Association Studies and Common Disease — Realizing Clinical Utility

article

Genomic analysis of Plasmodium vivax in southern Ethiopia reveals selective pressures in multiple parasite mechanisms

scientific article published on 01 October 2019

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

scientific article

Germs, genomes and genealogies

scientific article

Graphical Model Selection for Gaussian Conditional Random Fields in the Presence of Latent Variables

scientific article published on 11 July 2018

High recombination rates and hotspots in a Plasmodium falciparum genetic cross

scientific article published on 4 April 2011

High-throughput microbial population genomics using the Cortex variation assembler

scientific article

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I

scientific article published on 28 May 2013

Human genome sequence variation and the influence of gene history, mutation and recombination

scientific article

Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences

scientific article

Hypervariable antigen genes in malaria have ancient roots

scientific article

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank

scientific article published on 23 December 2019

Inferring the ancestry of everyone

Inferring whole-genome histories in large population datasets

scientific article published on 02 September 2019

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes

scientific article published on 15 May 2013

Integrating long-range connectivity information into de Bruijn graphs

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

scientific article

LOW-BIAS RNA SEQUENCING OF THE HIV-2 GENOME FROM BLOOD PLASMA

article

LOW-BIAS RNA SEQUENCING OF THE HIV-2 GENOME FROM BLOOD PLASMA

MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia

Mapping copy number variation by population-scale genome sequencing

scientific article

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

scientific article published on 21 October 2009

Mapping the drivers of within-host pathogen evolution using massive data sets

scientific article published on 09 July 2019

Multi-population classical HLA type imputation

scientific article

Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3

scientific article published on 19 May 2011

Multiple instances of ancient balancing selection shared between humans and chimpanzees

scientific article

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

scientific article published on 28 April 2013

Nonhuman genetics. Strong male bias drives germline mutation in chimpanzees

scientific article

Population genomics of the immune evasion (var) genes of Plasmodium falciparum

scientific article

Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease

scientific article

Publisher Correction: Inferring whole-genome histories in large population datasets

scientific article published on 01 November 2019

Real-time search of all bacterial and viral genomic data

Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development

scientific article (publication date: 2012)

Recombination hotspots and population structure in Plasmodium falciparum

scientific article

Recombination rate estimation in the presence of hotspots

scientific article published on 10 July 2007

Reply to: "FaST-LMM-Select for addressing confounding from spatial structure and rare variants".

scientific article published in May 2013

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes

scientific article published on 24 October 2018

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Structural and regulatory diversity shape HLA-C protein expression levels

scientific article

Systematic classification of shared components of genetic risk for common human diseases

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

scientific article

The fine-scale structure of recombination rate variation in the human genome

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes

scientific article published on 11 March 2013

The origins and relatedness structure of mixed infections vary with local prevalence of malaria

scientific article published on 12 July 2019

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

scientific article

Ultrafast search of all deposited bacterial and viral genomic data

scientific article published on 04 February 2019

Use of population genetic data to infer oviposition behaviour: species-specific patterns in four oak gallwasps (Hymenoptera: Cynipidae).

scientific article published in February 2002

Whole-exome sequencing studies of nonfunctioning pituitary adenomas

scientific article published on 28 February 2013

Whole-exome sequencing studies of nonhereditary (sporadic) parathyroid adenomas

scientific article

Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline.

scientific article

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