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List of works by Gilbert Vassart

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

scientific article

A family with a novel TSH receptor activating germline mutation (p.Ala485Val).

scientific article published on 4 January 2008

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism

scientific article

A molecular dissection of the glycoprotein hormone receptors.

scientific article published on March 2004

A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.

scientific article published on March 2004

A physiological role for the posttranslational cleavage of the thyrotropin receptor?

scientific article published on January 2004

Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors

scientific article published on 01 January 2005

Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist

scientific article published on 01 April 2002

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers

scientific article published on 7 February 2006

Allosteric properties of G protein-coupled receptor oligomers

scientific article published on 27 June 2007

An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor

scientific article

An in vivo demonstration of functional G protein-coupled receptor dimers

scientific article

Analysis of C-terminally substituted tachykinin-like peptide agonists by means of aequorin-based luminescent assays for human and insect neurokinin receptors

scientific article

Autonomous adenomas caused by somatic mutations of the thyroid-stimulating hormone receptor in children.

scientific article published on 30 January 2014

CCR5 and HIV infection

scientific article

Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid

scientific article

Commentary: Thyrotropin Stimulates Differentiation Not Proliferation of Normal Human Thyrocytes in Culture

scientific article published on 25 August 2017

Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands

scientific article published on 4 July 2007

Defective postnatal development of the male reproductive tract in LGR4 knockout mice

scientific journal article

Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity

scientific article published on 19 August 2004

Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

scientific article

Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers

scientific article published in Nature Communications

Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers

scientific article published on 27 October 2004

Evolutionary conservation of bursicon in the animal kingdom.

scientific article published on 27 December 2006

Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell lines

scientific article published on November 2002

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

scientific article (publication date: 11 July 2003)

G protein-coupled receptors: mutations and endocrine diseases

scientific article published on 08 February 2011

GPR3 receptor, a novel actor in the emotional-like responses

scientific article

GRIS: glycoprotein-hormone receptor information system

scientific article published on 16 March 2006

Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization

scientific article published on 01 November 2006

Genotypic and gene expression studies in congenital melanocytic nevi: insight into initial steps of melanotumorigenesis

scientific article

Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

scientific article

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

scientific article

Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

scientific article

Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1.

scientific article

Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome

scientific article published on 01 January 2008

LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea

scientific article

Lack of minocycline efficiency in genetic models of Huntington's disease

scientific article published on January 2007

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene

scientific article

Leydig Cell Tumors in Children: Contrasting Clinical, Hormonal, Anatomical, and Molecular Characteristics in Boys and Girls ⬇️

scientific article published on June 23, 2012

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo ⬇️

scientific article published on April 21, 2011

Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.

scientific article

Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.

scientific article published on 27 May 2004

Monoclonal antibodies with thyroid stimulating activity, at last

scientific article published on 01 December 2002

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

scientific article

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.

scientific article published on 10 March 2005

Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity

scientific article published in July 2005

Non-peptide arginine-vasopressin antagonists: the vaptans

scientific article

Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor.

scientific article published in August 2003

Possible non-Mendelian mechanisms of thyroid dysgenesis.

scientific article published on January 2007

Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism

scientific article published in December 2004

Premature ovarian aging in mice deficient for Gpr3.

scientific article

Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+ -levels in Drosophila S2 cells

scientific article published on November 2001

Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.

scientific article

Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA

scientific article

Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids

scientific article

Specificity and promiscuity of gonadotropin receptors.

scientific article

Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues

scientific article published on 10 August 2006

Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor.

scientific article published on July 2004

The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.

scientific article

The Thyrotropin Receptor and the Regulation of Thyrocyte Function and Growth*

scientific article (publication date: August 1992)

Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands

scientific article

Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage

scientific article published on 17 March 2016

Understanding ovarian hyperstimulation syndrome

scientific article

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