Search filters

List of works by Michelle A Lowes

A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity

scientific article published on 01 August 2018

A randomized clinical trial in vitamin D-deficient adults comparing replenishment with oral vitamin D3 with narrow-band UV type B light: effects on cholesterol and the transcriptional profiles of skin and blood.

scientific article published on 22 February 2017

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin

scientific article published on 26 January 2012

A subpopulation of CD163-positive macrophages is classically activated in psoriasis

scientific article

African American Patients With Hidradenitis Suppurativa Have Significant Health Care Disparities: A Retrospective Study

scientific article published on 01 May 2019

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

scientific article published on 7 June 2007

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

scientific article

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

scientific article

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

article

Are bacteria infectious pathogens in hidradenitis suppurativa (HS)? Debate at the Symposium for Hidradenitis Suppurativa Advances meeting (November 2017)

scientific article published on 08 November 2018

Benign melanocytic proliferative nodule within a congenital naevus

scientific article published on 01 May 2000

Blockade of CD11a by Efalizumab in Psoriasis Patients Induces a Unique State of T-Cell Hyporesponsiveness

scientific article published on 31 January 2008

CARD14 expression in dermal endothelial cells in psoriasis

scientific article

CARD14-Mediated Psoriasis and Pityriasis Rubra Piliaris (PRP)

Cellular Genomic Maps Help Dissect Pathology in Human Skin Disease

scientific article published on 11 October 2007

Correction to: Pain, Psychological Comorbidities, Disability, and Impaired Quality of Life in Hidradenitis Suppurativa

scientific article

Current concepts in the immunopathogenesis of psoriasis

scientific article published in October 2004

Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases

scientific article

Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis

scientific article published on 3 August 2015

Defining lesional, perilesional and unaffected skin in hidradenitis suppurativa: proposed recommendations for clinical trials and translational research studies

scientific article published on 29 August 2019

Distribution of Self-reported Hidradenitis Suppurativa Age at Onset

scientific article published on 05 June 2019

Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin

scientific article published in October 2004

Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques

scientific article

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

scientific article

Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series.

scientific article

Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA).

scientific article

Exploring changes in placebo treatment arms in hidradenitis suppurativa randomized clinical trials: A systematic review

scientific article published on 29 May 2019

Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses

scientific article published on 15 November 2012

Hemoglobin as an indicator of disease activity in severe hidradenitis suppurativa

scientific article published on 10 August 2018

Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1β.

scientific article

Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment.

scientific article

Humanized anti–IFN-γ (HuZAF) in the treatment of psoriasis

scientific article published on 29 July 2014

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

scientific article

IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis

scientific article published on 30 April 2013

Identification of Cellular Pathways of "Type 1," Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis

scientific article published on 01 February 2008

Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis

scientific article

Immunology of psoriasis

scientific article

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

scholarly article

Inflammation: A Contributor to Depressive Comorbidity in Inflammatory Skin Disease

scientific article published on 28 June 2018

Integrating the skin and blood transcriptomes and serum proteome in hidradenitis suppurativa reveals complement dysregulation and a plasma cell signature

scientific article published in PLoS ONE

Isotretinoin treatment in a patient with known peanut allergy and positive IgE test results for soybean

scientific article published on 23 September 2016

Keratoacanthomas have an immunosuppressive cytokine environment of increased IL-10 and decreased GM-CSF compared to squamous cell carcinomas.

scientific article published on July 1999

Lack of Functionally Active Melan-A26–35-Specific T Cells in the Blood of HLA-A2+ Vitiligo Patients

scientific article published on 13 March 2008

Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis

scientific article

Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.

scientific article published on May 2007

Major gaps in understanding and treatment of hidradenitis suppurativa.

scientific article published on June 2017

Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease

scientific article

Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets

scientific article published on January 2016

Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation

scientific article

Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

scientific article published on September 2007

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management

scientific article published on 11 March 2019

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management

scientific article published on 11 March 2019

Novel insight into the agonistic mechanism of alefacept in vivo: differentially expressed genes may serve as biomarkers of response in psoriasis patients

scientific article published on June 2007

PSORS2 is due to mutations in CARD14.

scientific article

Pain, Psychological Comorbidities, Disability, and Impaired Qualify of Life in Hidradenitis Suppurativa

scientific article published in November 2017

Pathogenesis and therapy of psoriasis

scientific article published on February 2007

Pathophysiology of hidradenitis suppurativa.

scientific article published on June 2017

Patients With Psoriasis and Personalized Trade-offs in Treatment Decisions-Lessons Learned From Focus Groups

scientific article published on 30 March 2016

Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept

scientific article

Polyclonal hyperglobulinaemia and elevated acute-phase reactants in hidradenitis suppurativa.

scientific article

Post-therapeutic relapse of psoriasis after CD11a blockade is associated with T cells and inflammatory myeloid DCs

scientific article (publication date: 2012)

Proceeding report of the Second Symposium on Hidradenitis Suppurativa Advances (SHSA) 2017

scientific article published on 01 January 2019

Proceeding report of the Symposium on Hidradenitis Suppurativa Advances (SHSA).

scientific article published on 12 September 2017

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018

scientific article published on 29 April 2019

Prominent Production of IL-20 by CD68+/CD11c+ Myeloid-Derived Cells in Psoriasis: Gene Regulation and Cellular Effects

article

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

scientific article published on 17 January 2008

Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

scientific article published on 17 July 2008

Psoriasis vulgaris flare during efalizumab therapy does not preclude future use: a case series

scientific article

Putting together the psoriasis puzzle: an update on developing targeted therapies ⬇️

scientific article published on July 1, 2012

Quality of life and sexual health in patients with hidradenitis suppurativa☆☆☆.

scientific article published in February 2018

Quantitative reverse transcriptase-PCR amplification of cytokine mRNA in liver biopsy specimens using a non-competitive method

scientific article published on 01 April 1997

Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

scientific article

Reduction of Inflammatory and Cardiovascular Proteins in the Blood of Patients with Psoriasis: Differential Responses between Tofacitinib and Etanercept after 4 Weeks of Treatment.

scientific article published on 16 September 2017

Regression of melanoma, but not keratoacanthoma, is associated with increased HLA-B22 and decreased HLA-B27 and HLA-DR1

scientific article published on 01 December 1999

Resident and "inflammatory" dendritic cells in human skin

scientific article published on 14 August 2008

Resolved psoriasis lesions retain expression of a subset of disease-related genes

scientific article

T Helper 1 Cytokine mRNA Is Increased in Spontaneously Regressing Primary Melanomas

scientific article published on 01 June 1997

TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques

scientific article published on 01 August 2005

TREM-1 as a potential therapeutic target in psoriasis

scientific article published on 13 February 2013

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

scientific article published on 05 August 2008

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

scientific article published on 03 January 2013

The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes

scientific article published on 13 May 2016

The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012.

scientific article published on August 2013

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases

scientific article published on 22 December 2015

Transient reactive papulotranslucent acrokeratoderma associated with cystic fibrosis

scientific article published on 01 August 2000

Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated

scientific article published on 10 February 2011

Paulina is supported by:

About Paulina

Help