List of works - Christian Rummey

3D QSAR investigations on antimalarial naphthylisoquinoline alkaloids by comparative molecular similarity indices analysis (CoMSIA), based on different alignment approaches

scientific article published on January 2003

Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study

scientific article

Characterization of pulmonary function in 10-18 year old patients with Duchenne muscular dystrophy.

scientific article published on 6 January 2017

Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.

scientific article

Effects of idebenone on color vision in patients with leber hereditary optic neuropathy.

scientific article

Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial

scientific article

Evaluation of extended parameter sets for the 3D-QSAR technique MaP: implications for interpretability and model quality exemplified by antimalarially active naphthylisoquinoline alkaloids

scientific article published in May 2003

Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I ⬇️

scientific article published on April 27, 2012

Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site

scientific article published on 01 January 2007

Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA)

scientific article published on 31 January 2011

Idebenone reduces respiratory complications in patients with Duchenne muscular dystrophy

scientific article published on 12 May 2016

In silico fragment-based discovery of DPP-IV S1 pocket binders

scientific article published on 01 March 2006

On the 6-endo selectivity in 4-penten-1-oxyl radical cyclizations.

scientific article published in September 2004

On the stereoselectivity of 4-penten-1-oxyl radical 5-exo-trig cyclizations.

scientific article

Rating disease progression of Friedreich's ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database.

scientific article published on January 2013

Synthesis of enantiopure axially chiral C3-symmetric tripodal ligands and their application as catalysts in the asymmetric addition of dialkylzinc to aldehydes

scientific article published on 01 September 2003

Test-retest reliability of the Friedreich's ataxia rating scale

scientific article published on 11 August 2020

The heart in Friedreich ataxia: definition of cardiomyopathy, disease severity, and correlation with neurological symptoms.

scientific article published on 29 February 2012

The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia ⬇️

scientific article published on August 28, 2011

The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.

scientific article published on 11 January 2006

Treatment effect of idebenone on inspiratory function in patients with Duchenne muscular dystrophy

scientific article

List of works by Christian Rummey

3D QSAR investigations on antimalarial naphthylisoquinoline alkaloids by comparative molecular similarity indices analysis (CoMSIA), based on different alignment approaches

Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study

Characterization of pulmonary function in 10-18 year old patients with Duchenne muscular dystrophy.

Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.

Effects of idebenone on color vision in patients with leber hereditary optic neuropathy.

Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial

Evaluation of extended parameter sets for the 3D-QSAR technique MaP: implications for interpretability and model quality exemplified by antimalarially active naphthylisoquinoline alkaloids

Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I ⬇️

Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site

Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA)

Idebenone reduces respiratory complications in patients with Duchenne muscular dystrophy

In silico fragment-based discovery of DPP-IV S1 pocket binders

On the 6-endo selectivity in 4-penten-1-oxyl radical cyclizations.

On the stereoselectivity of 4-penten-1-oxyl radical 5-exo-trig cyclizations.

Rating disease progression of Friedreich's ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database.

Synthesis of enantiopure axially chiral C3-symmetric tripodal ligands and their application as catalysts in the asymmetric addition of dialkylzinc to aldehydes

Test-retest reliability of the Friedreich's ataxia rating scale

The heart in Friedreich ataxia: definition of cardiomyopathy, disease severity, and correlation with neurological symptoms.

The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia ⬇️

The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors.

Treatment effect of idebenone on inspiratory function in patients with Duchenne muscular dystrophy