List of works - Anne Bertolotti

An evolutionarily conserved pathway controls proteasome homeostasis

scientific journal article

An inducible chaperone adapts proteasome assembly to stress

scientific article

Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response

scientific article published on 25 April 2022

Coping with Protein Quality Control Failure

scientific article

Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.

scientific article published on 14 September 2006

Decoding the Protein Destruction Code: A Panoramic View

scientific article published in September 2016

Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors.

scientific article published on 31 July 2017

Erratum: Corrigendum: Sustained translational repression by eIF2α-P mediates prion neurodegeneration

scientific article published in Nature

Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention ⬇️

scientific article published on March 14, 2012

Exposure of hydrophobic surfaces initiates aggregation of diverse ALS-causing superoxide dismutase-1 mutants

scientific article

Failure of amino acid homeostasis causes cell death following proteasome inhibition.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

scientific article

Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity.

scientific article

Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones

scientific journal article

Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

scientific article

Prion Properties of SOD1 in Amyotrophic Lateral Sclerosis and Potential Therapy

scientific article published on 17 January 2017

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

scientific article

Prion-like protein aggregates exploit the RHO GTPase to cofilin-1 signaling pathway to enter cells.

scientific article published in March 2018

Propagation of the prion phenomenon: beyond the seeding principle.

scientific article published on 05 January 2012

Regulation of proteasome assembly and activity in health and disease

scientific article published on 01 November 2018

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

scientific article

Self-propagation and transmission of misfolded mutant SOD1: prion or prion-like phenomenon?

scientific article published on 01 June 2011

Surviving protein quality control catastrophes--from cells to organisms

scientific article

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

scientific article

Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B

scientific article published on 26 July 2018

Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation.

scholarly article

The split protein phosphatase system

scholarly article by Anne Bertolotti published in December 2018

qMotor, a set of rules for sensitive, robust and quantitative measurement of motor performance in mice.

scientific article published on 29 June 2016

List of works by Anne Bertolotti

An evolutionarily conserved pathway controls proteasome homeostasis

An inducible chaperone adapts proteasome assembly to stress

Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response

Coping with Protein Quality Control Failure

Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.

Decoding the Protein Destruction Code: A Panoramic View

Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors.

Erratum: Corrigendum: Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Exploiting the selectivity of protein phosphatase 1 for pharmacological intervention ⬇️

Exposure of hydrophobic surfaces initiates aggregation of diverse ALS-causing superoxide dismutase-1 mutants

Failure of amino acid homeostasis causes cell death following proteasome inhibition.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity.

Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones

Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

Prion Properties of SOD1 in Amyotrophic Lateral Sclerosis and Potential Therapy

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

Prion-like protein aggregates exploit the RHO GTPase to cofilin-1 signaling pathway to enter cells.

Propagation of the prion phenomenon: beyond the seeding principle.

Regulation of proteasome assembly and activity in health and disease

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

Self-propagation and transmission of misfolded mutant SOD1: prion or prion-like phenomenon?

Surviving protein quality control catastrophes--from cells to organisms

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B

Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation.

The split protein phosphatase system

qMotor, a set of rules for sensitive, robust and quantitative measurement of motor performance in mice.